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Institutional Repository of the Lisbon Polytechnic

 

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The aim of this Scientific Repository is to disseminate the scientific production produced by the Instituto Politécnico de Lisboa academic community, to increase the visibility and the investigation impact, to ensure the storage of the intellectual memory and to promote the open access to the information.

Recent Submissions

Indoor air quality in a home improvement store: gaseous pollutants, bioburden and particle-bound chemical constituents
Publication . Furst, Leonardo; Cipoli, Yago; Yubero, Eduardo; Galindo, Nuria; Viegas, Carla; Dias, Marta; Nunes, Teresa; Igrejas, Getúlio; Feliciano, Manuel; Alves, Célia; Viegas, Carla
This paper provides a comprehensive assessment of indoor and outdoor air quality within a home improvement and gardening store chain in northeastern Portugal. In December 2021 and January 2022, two multipollutant systems were installed in the store and outdoors to assess air quality. Continuous monitoring included particulate matter below 10 µm (PM10), CO2, and comfort parameters. PM10 samples were collected using gravimetric samplers during both occupied and vacant periods. These samples were then analysed for carbonaceous constituents and metal(loid)s. Additionally, volatile organic compounds (VOCs), carbonyls, bacteria, and fungi were passively sampled. Results showed higher indoor concentrations of PM10 during labour hours (45.4 ± 15.2 μg/m3), while outdoor values of 27.1 ± 9.96 μg/m3 were recorded. The elemental characterisation of PM10 revealed a high abundance of soil-related elements indoors, suggesting that resuspension is one of the primary sources. The most abundant elements were Ca, Fe, and Zn, with concentrations of 658 ± 297, 273 ± 141, and 172 ± 67.4 ng/m³, respectively. Outdoors, elements related to tyre and brake wear, and road dust were predominant, indicating emissions from non-exhaust traffic emissions as the main source. A prevalence of α-pinene, limonene, and hexanal was found indoors, most likely related to wood products. Fungi with clinical relevance toxigenic potential and higher bacterial loads were observed in the gardening and heating sectors of the store. This study underscores the importance of investigating less-studied stores, as they may exhibit pollutant levels that exceed health protection thresholds.
Quality of life associated with breathlessness in the multinational Burden of Obstructive Lung Disease (BOLD) study: a cross-sectional analysis
Publication . Müller, Alexander; Wouters, Emiel F.; Burney, Peter; Potts, James; Cardoso, Joao; Al Ghobain, Mohammed; Studnicka, Michael; Obaseki, Daniel; Elsony, Asma; Mortimer, Kevin; Mannino, David; Jögi, Rain; Ahmed, Rana; Nafees, Asaad; Hermínia Brites Dias
Introduction: Evidence of an association between breathlessness and quality of life from population-based studies is limited. We aimed to investigate the association of physical and mental quality of life with breathlessness across several low-, middle- and high-income countries. Methods: We analyzed data from 19,714 adults (31 sites, 25 countries) from the Burden of Obstructive Lung Disease (BOLD) study. We measured both mental and physical quality of life components using the SF-12 questionnaire and defined breathlessness as grade ≥2 on the modified Medical Research Council scale. We used multivariable linear regression to assess the association of each quality-of-life component with breathlessness. We pooled site-specific estimates using random-effects meta-analysis. Results: Both physical and mental component scores were lower in participants with breathlessness compared to those without. This association was stronger for the physical component (coefficient = -7.59; 95%CI -8.60, -6.58; I2 = 78.5%) than for the mental component (coefficient = -3.50; 95%CI -4.36, -2.63; I2 = 71.4%). The association between physical components and breathlessness was stronger in high-income countries (coefficient = -8.82; 95%CI -10.15, -7.50). Heterogeneity across sites was partly explained by sex and tobacco smoking. Conclusion: Quality of life is worse in people with breathlessness, but this association varies widely across the world.
Práticas e conceções da História e da didática da História na formação de professores do Ensino Básico (2º CEB): estudo de caso da Escola Superior de Educação de Lisboa
Publication . Gomes Dias, Alfredo
O trabalho que agora se apresenta tem origem na investigação realizada no âmbito do curso de Doutoramento em Educação frequentado na Universidade Autónoma de Barcelona (UAB), entre 2016 e 2019, integrada na linha de investigação “Formação do pensamento social, histórico e geográfico, e educação para a cidadania”. Esta investigação teve a orientação científica do Professor Joan Pagès i Blanch. O texto original desta tese de doutoramento – Practicas y concepciones de la historia y de la didáctica de la historia en la formación de maestros de la enseñanza básica (10‑12 años). Estudio de caso de la Escola Superior de Educaçã o de Lisboa – encontra‑se disponível no repositório da UAB: imprimirFicheroTesis.do (educacion.gob.es) Nesta versão, que foi apresentada na UAB em provas públicas, no dia 12 de setembro de 2019, podem ser consultados os anexos que reúnem os documentos de suporte às atividades investigativas e que estão ausentes nesta edição impressa.
Early mortality prediction in intensive care unit patients based on serum metabolomic fingerprint
Publication . Araújo, Rúben Alexandre Dinis; Ramalhete, Luís; Von Rekowski, Cristiana; Henrique Fonseca, Tiago Alexandre; Bento, Luís; Calado, Cecília
Predicting mortality in intensive care units (ICUs) is essential for timely interventions and efficient resource use, especially during pandemics like COVID-19, where high mortality persisted even after the state of emergency ended. Current mortality prediction methods remain limited, especially for critically ill ICU patients, due to their dynamic metabolic changes and heterogeneous pathophysiological processes. This study evaluated how the serum metabolomic fingerprint, acquired through Fourier-Transform Infrared (FTIR) spectroscopy, could support mortality prediction models in COVID-19 ICU patients. A preliminary univariate analysis of serum FTIR spectra revealed significant spectral differences between 21 discharged and 23 deceased patients; however, the most significant spectral bands did not yield high-performing predictive models. By applying a Fast-Correlation-Based Filter (FCBF) for feature selection of the spectra, a set of spectral bands spanning a broader range of molecular functional groups was identified, which enabled Naïve Bayes models with AUCs of 0.79, 0.97, and 0.98 for the first 48 h of ICU admission, seven days prior, and the day of the outcome, respectively, which are, in turn, defined as either death or discharge from the ICU. These findings suggest FTIR spectroscopy as a rapid, economical, and minimally invasive diagnostic tool, but further validation is needed in larger, more diverse cohorts.
Três décadas da qualidade em saúde: que futuro?
Publication . França, Margarida; Eiras , Margarida
Nos dias de hoje, a Qualidade em Saúde não está dissociada da Segurança do Doente, cujo movimento surge com a publicação do Relatório To err is Human. Desde essa altura que as políticas de saúde, tanto ao nível internacional como nacional, têm uma preocupação crescente com a avaliação e a melhoria dos cuidados de saúde. Este documento aborda as Políticas Públicas e a Qualidade em Saúde, bem como o movimento da Segurança do Doente e as ações desenvolvidas em Portugal nos últimos anos. Finalizamos com propostas de desenvolvimento que poderão contribuir para uma reflexão sobre o futuro da Qualidade e Segurança em Portugal.