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Assessment of DNA damage and oxidative stress of green tea epigallocatechin-3-gallate (EGCG) by comet assay

2024-09Conference poster Open access
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datacite.subject.sdg03:Saúde de Qualidade
dc.contributor.authorLadeira, Carina
dc.contributor.authorRamos, Carina
dc.contributor.authorPádua, Mário
dc.contributor.authorRibeiro, Edna
dc.date.accessioned2025-04-10T08:48:23Z
dc.date.available2025-04-10T08:48:23Z
dc.date.issued2024-09
dc.descriptionSupported by H&TRC- Health & Technology Research Center- Escola Superior de Tecnologia da Saúde, Instituto Politécnico de Lisboa. H&TRC authors gratefully acknowledge the FCT/MCTES national support through the UIDP/05608/2020, and UIDB/05608/2020.
dc.description.abstractIntroduction: EGCG, the primary polyphenol in green tea, has been shown to inhibit cancer cell growth and tumorigenesis in vitro and animal models, particularly by eliminating cancer cells through induction of apoptosis and protecting normal cells against genotoxic hazards. However, increasing evidence indicates that EGCG produces ROS. Aim of the study: Evaluate DNA damage and oxidative damage, measured by comet assay; lipid profile, liver function parameters, and vitamins A and E levels during an interventional study with 90 days (T0 and T90) duration (T0 and T90) in 30 individuals with an EGCG intake of 225 mg/day.eng
dc.identifier.citationLadeira C, Ramos C, Pádua M, Ribeiro E. Assessment of DNA damage and oxidative stress of green tea epigallocatechin-3-gallate (EGCG) by comet assay. In: 52nd Congress of the European Environmental Mutagenesis and Genomics Society (EEMGS), Rovinj (Croatia), September 23-27, 2024.
dc.identifier.urihttp://hdl.handle.net/10400.21/21798
dc.language.isoeng
dc.peerreviewedyes
dc.relation.hasversionhttps://eemgs.eu/news-new/52nd-eemgs-icaw-meeting-2024/
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectDNA damage
dc.subjectOxidative damage
dc.subjectGreen tea
dc.subjectEpigallocatechin-3-gallate
dc.subjectFCT_UIDP/05608/2020
dc.subjectFCT_UIDB/05608/2020
dc.titleAssessment of DNA damage and oxidative stress of green tea epigallocatechin-3-gallate (EGCG) by comet assayeng
dc.typeconference poster
dspace.entity.typePublication
oaire.citation.conferenceDate2024-09
oaire.citation.conferencePlaceRovinj, Croácia
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyNameLadeira
person.familyNameRibeiro
person.givenNameCarina
person.givenNameEdna
person.identifier144237
person.identifier.ciencia-id801C-1BBA-1D9E
person.identifier.ciencia-idC414-CDF2-D35A
person.identifier.orcid0000-0001-5588-0074
person.identifier.orcid0000-0003-1316-7750
person.identifier.ridJ-2572-2012
person.identifier.scopus-author-id36463788000
relation.isAuthorOfPublication1aef4b60-4197-436b-84ab-80d31cbaed33
relation.isAuthorOfPublicationa571bf34-bcda-49ca-b5cb-4cdecbb3d9c7
relation.isAuthorOfPublication.latestForDiscovery1aef4b60-4197-436b-84ab-80d31cbaed33

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