| Nome: | Descrição: | Tamanho: | Formato: | |
|---|---|---|---|---|
| 1.41 MB | Adobe PDF |
Orientador(es)
Resumo(s)
Crohn’s disease (CD) is an inflammatory bowel disease. Previous research has explored the impact of diet on CD, as specific dietary components can influence gut microbiota and immune responses, contributing to damage in the gastrointestinal tract. The Crohn’s Disease Exclusion Diet (CDED) is based on an exclusion diet; it is a recent dietary approach that is often used alongside partial enteral nutrition (PEN) and aims to induce disease remission by excluding certain dietary components. This study assesses the current evidence for the effectiveness of the CDED + PEN in achieving remission in both children and adults with active CD. Our systematic review followed PRISMA recommendations and was registered in PROSPERO with CRD number 42022335076. The searched databases were PubMed/MEDLINE, Cochrane Library, Scopus, and Web of Science. The included studies were analyzed using Rayyan software, and the risk of bias was assessed with Cochrane RevMan 5.0 software. The primary assessed outcome was clinical remission, evaluated with validated questionnaire scores such as PCDAI, CDAI, or HBI. All analyzed papers yielded promising results. Notably, the CDED + PEN demonstrated better tolerance than exclusive enteral nutrition (EEN), resulting in higher adherence rates. Therefore, the CDED + PEN appears to be a viable alternative for induction remission in active disease for both children and adults with CD.
Descrição
This study was part of the MSc thesis in Clinical Nutrition of one of the authors (I.C.) (supervisor, A.C.M.; co-supervisor, G.R.) from Faculty of Medicine of Lisbon and Escola Superior de Tecnologia da Saúde de Lisboa, Lisbon, Portugal. The H&TRC author gratefully acknowledges the FCT/MCTES national support through UIDB/05608/2020 and UIDP/05608/2020.
Palavras-chave
Nutrition Crohn disease Exclusive enteral nutrition Partial enteral nutrition Enteral nutrition Crohn's disease exclusion diet Remission FCT_UIDB/05608/2020 FCT_UIDP/05608/2020
Contexto Educativo
Citação
Correia I, Oliveira PA, Antunes ML, Raimundo MG, Moreira AC. Is there evidence of Crohn’s disease exclusion diet (CDED) in remission of active disease in children and adults? A systematic review. Nutrients. 2024;16(7):987.
Editora
MDPI