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Is there evidence of Crohn’s disease exclusion diet (CDED) in remission of active disease in children and adults? A systematic review

2024-03Journal article Open access
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dc.contributor.authorCorreia, Inês
dc.contributor.authorOliveira, Patrícia
dc.contributor.authorAntunes, Maria Da Luz
dc.contributor.authorRaimundo, Maria da Graça
dc.contributor.authorMoreira, Ana Catarina
dc.date.accessioned2024-04-03T11:56:41Z
dc.date.available2024-04-03T11:56:41Z
dc.date.issued2024-03
dc.descriptionThis study was part of the MSc thesis in Clinical Nutrition of one of the authors (I.C.) (supervisor, A.C.M.; co-supervisor, G.R.) from Faculty of Medicine of Lisbon and Escola Superior de Tecnologia da Saúde de Lisboa, Lisbon, Portugal. The H&TRC author gratefully acknowledges the FCT/MCTES national support through UIDB/05608/2020 and UIDP/05608/2020.pt_PT
dc.description.abstractCrohn’s disease (CD) is an inflammatory bowel disease. Previous research has explored the impact of diet on CD, as specific dietary components can influence gut microbiota and immune responses, contributing to damage in the gastrointestinal tract. The Crohn’s Disease Exclusion Diet (CDED) is based on an exclusion diet; it is a recent dietary approach that is often used alongside partial enteral nutrition (PEN) and aims to induce disease remission by excluding certain dietary components. This study assesses the current evidence for the effectiveness of the CDED + PEN in achieving remission in both children and adults with active CD. Our systematic review followed PRISMA recommendations and was registered in PROSPERO with CRD number 42022335076. The searched databases were PubMed/MEDLINE, Cochrane Library, Scopus, and Web of Science. The included studies were analyzed using Rayyan software, and the risk of bias was assessed with Cochrane RevMan 5.0 software. The primary assessed outcome was clinical remission, evaluated with validated questionnaire scores such as PCDAI, CDAI, or HBI. All analyzed papers yielded promising results. Notably, the CDED + PEN demonstrated better tolerance than exclusive enteral nutrition (EEN), resulting in higher adherence rates. Therefore, the CDED + PEN appears to be a viable alternative for induction remission in active disease for both children and adults with CD.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationCorreia I, Oliveira PA, Antunes ML, Raimundo MG, Moreira AC. Is there evidence of Crohn’s disease exclusion diet (CDED) in remission of active disease in children and adults? A systematic review. Nutrients. 2024;16(7):987.pt_PT
dc.identifier.doi10.3390/nu16070987pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.21/17248
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherMDPIpt_PT
dc.relation.publisherversionhttps://www.mdpi.com/2072-6643/16/7/987pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectNutritionpt_PT
dc.subjectCrohn diseasept_PT
dc.subjectExclusive enteral nutritionpt_PT
dc.subjectPartial enteral nutritionpt_PT
dc.subjectEnteral nutritionpt_PT
dc.subjectCrohn's disease exclusion dietpt_PT
dc.subjectRemissionpt_PT
dc.subjectFCT_UIDB/05608/2020pt_PT
dc.subjectFCT_UIDP/05608/2020pt_PT
dc.titleIs there evidence of Crohn’s disease exclusion diet (CDED) in remission of active disease in children and adults? A systematic reviewpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue7pt_PT
oaire.citation.startPage987pt_PT
oaire.citation.titleNutrientspt_PT
oaire.citation.volume16pt_PT
person.familyNameAlmeida Oliveira
person.familyNameAntunes
person.familyNameMoreira
person.givenNamePatrícia
person.givenNameMaria Luz
person.givenNameAna Catarina
person.identifier2087122
person.identifier.ciencia-id421B-C686-77E0
person.identifier.ciencia-idB111-6F38-5904
person.identifier.ciencia-idC81E-CC41-DFB0
person.identifier.orcid0000-0003-2844-8934
person.identifier.orcid0000-0003-0942-7601
person.identifier.orcid0000-0001-7031-6738
person.identifier.ridB-8661-2015
person.identifier.scopus-author-id57202291460
person.identifier.scopus-author-id16234261500
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication1ffb19f2-5505-4dd2-81a2-6992a372d11b
relation.isAuthorOfPublicationdce3e466-ad17-4bea-8b95-4a5b9bb22910
relation.isAuthorOfPublicationcdce3e88-b09d-40b9-bad5-29d1d3610f69
relation.isAuthorOfPublication.latestForDiscoverycdce3e88-b09d-40b9-bad5-29d1d3610f69

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