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Evaluating the impact of using natural fixative agents as alternatives to formaldehyde in histopathology: a systematic review

2025-03Conference poster Open access
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datacite.subject.sdg03:Saúde de Qualidade
dc.contributor.authorHorta, Andreia
dc.contributor.authorCondesso, Nádia
dc.contributor.authorMaia-Matos, Mário
dc.contributor.authorBorges-Ferro, A
dc.date.accessioned2025-12-23T09:24:42Z
dc.date.available2025-12-23T09:24:42Z
dc.date.issued2025-03
dc.description.abstractThe histological technique involves several steps to prepare tissues for microscopic analysis, with fixation being one of the key steps. Formaldehyde is the most used fixing agent; however, it poses significant health risks and is classified as a Group 1 human carcinogen by the IARC and the NTP. This concern has prompted the search for safer alternatives. This study aims to identify a less harmful natural substitute for formaldehyde that can reduce or eliminate exposure to this hazardous reagent. To achieve this objective, a systematic review explored the potential of natural fixatives that can perform similar functions with lower toxicity.eng
dc.identifier.citationHorta A, Condesso N, Maia-Matos M, Borges-Ferro A. Evaluating the impact of using natural fixative agents as alternatives to formaldehyde in histopathology: a systematic review. In: III Congresso Nacional da BioMedLab, Auditório Prof. Armando Simões dos Santos, Faculdade de Medicina Dentária, Universidade de Lisboa, 7 a 9 de março de 2025.
dc.identifier.urihttp://hdl.handle.net/10400.21/22401
dc.language.isoeng
dc.peerreviewedyes
dc.relation.hasversionhttps://biomedlab.pt/3-congresso/
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectHistopathology
dc.subjectFormaldehyde
dc.subjectNatural fixative agents
dc.subjectToxicity
dc.subjectSystematic review
dc.titleEvaluating the impact of using natural fixative agents as alternatives to formaldehyde in histopathology: a systematic revieweng
dc.typeconference poster
dspace.entity.typePublication
oaire.citation.conferenceDate2025-03
oaire.citation.conferencePlaceLisboa, Portugal
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyNameMaia-Matos
person.familyNameBORGES FERRO
person.givenNameMário
person.givenNameAMADEU JOSÉ
person.identifier.ciencia-id501A-A09D-5140
person.identifier.ciencia-idFA16-8351-EB4A
person.identifier.orcid0000-0002-3450-5758
relation.isAuthorOfPublication9a426513-2cfa-4c15-89eb-a38ee9f5aa16
relation.isAuthorOfPublicationf823b4bf-d2e4-456e-a7fa-b35180ff403f
relation.isAuthorOfPublication.latestForDiscovery9a426513-2cfa-4c15-89eb-a38ee9f5aa16

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