Browsing by resource type "conference paper"
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- As amputações realizadas em Portugal de 2000 a 2023: análise de uma realidadePublication . Matos, José Pedro; Matos, Mariana; Ramos, M. Rosário; Ricardo, Diogo; Carolino, ElisabeteAmputation, whether surgical or traumatic, entails the loss of a body segment due to irreparable injury caused by trauma, vascular conditions, or other pathologies. Among individuals with diabetes, amputation remains one of the most feared and recognized outcomes. However, early diagnosis and timely intervention could prevent approximately 50% of diabetes-related amputations and ulcerations. This retrospective observational cross-sectional study draws on data from the Hospital Morbidity Database (BDGDH), provided by the Central Administration of the Health System (ACSS) under the Ministry of Health. This study focuses on amputations in diabetic patients in Portugal, particularly from 2000 to 2023. It aims to update statistical results and projections using current data to inform health planning and optimize resource allocation. The research uses data from the Hospital Morbidity Database, analysing factors such as year, age group, gender, and diagnosis codes. Poisson regression and Negative Binomial models were applied to estimate annual amputation rates and forecast future trends. The findings will help compare national trends with international standards, guiding public health policies and supporting prevention and early diagnosis programs to reduce the socio-economic impact of amputations.
- Amputations in diabetics: statistical modelling and trends in Portugal (2000-2023)Publication . Carolino, Elisabete; Matos, José Pedro; Ricardo, Diogo; Ramos, M. RosárioAmputation, whether surgical or traumatic, entails the loss of a body segment due to irreparable injury caused by trauma, vascular conditions, or other pathologies. Among individuals with diabetes, amputation remains one of the most feared and recognized outcomes. However, early diagnosis and timely intervention could prevent approximately 50% of diabetes-related amputations and ulcerations. This retrospective observational cross-sectional study draws on data from the Hospital Morbidity Database (BDGDH), provided by the Central Administration of the Health System (ACSS) under the Ministry of Health. This study focuses on amputations in diabetic patients in Portugal, particularly from 2000 to 2023. It aims to update statistical results and projections using current data to inform health planning and optimize resource allocation. The research uses data from the Hospital Morbidity Database, analysing factors such as year, age group, gender, and diagnosis codes. Poisson regression and Negative Binomial models were applied to estimate annual amputation rates and forecast future trends. The findings will help compare national trends with international standards, guiding public health policies and supporting prevention and early diagnosis programs to reduce the socio-economic impact of amputations.
- Angioplastia pulmonar e Riociguat na hipertensão pulmonar tromboembólica crónica: o Deus ou o Diabo?Publication . Araújo, Patrícia C.; Pereira, E.; Coelho, André
- Aspergillus section Nigri in indoor environments: a silent sentinel for occupational and public healthPublication . Cervantes, Renata; Rodrigues, Cláudia; Pena, Pedro; Viegas, CarlaAspergillus section Nigri, a filamentous fungus within the Aspergillus genus, proliferates in organic matter-rich environments and produces dark-pigmented spores. While recognized for its metabolic versatility and industrial applications, Aspergillus section Nigri also presents significant public health concerns, particularly in environmental and occupational settings. The fungus is known to produce mycotoxins (Ochratoxin A (OTA); Fumonisins), which pose risks to human health, including respiratory disorders and allergic reactions. Its prevalence is notably elevated in occupational environments such as industrial facilities and laboratories, where favorable conditions (e.g., elevated humidity and temperature) facilitate its growth. This study aimed to assess the distribution of Aspergillus section Nigri across various indoor environments and evaluate its implications for public and occupational health. The research was conducted in eight different indoor settings, including nursing homes (n = 15), archives (n = 25), municipal waste collection vehicles (n = 168), grocery stores (n = 101), gyms (n = 67), cemeteries (n = 72), fire stations (n = 360), and coffee industry facilities (n = 58). A total of 866 samples were collected using active (Coriolis µ air sampler, Millipore) and passive (electrostatic dust collectors, surface swabs, and settled dust) methods. Fungal growth was promoted through incubation at 25 ± 2°C, and identification was performed using lactophenol cotton blue staining and microscopic analysis. The distribution of Aspergillus section Nigri will be analyzed across all sampled environments to determine prevalence and potential exposure risks. This study highlights the need for enhanced surveillance of Aspergillus section Nigri in indoor environments to mitigate occupational and public health risks. Prolonged exposure may contribute to respiratory and allergic conditions, particularly in vulnerable populations. Preventive measures should be prioritized to reduce exposure in high-risk settings.
- Biological agents risk assessment: how to close the gap between science, policy making and occupational health and safety practice?Publication . Colomo, Carlota Alejandre; Heussen, Henri; Van der Haar, Rudolf; Marchand, Geneviève; Madsen, Anne Mette; Viegas, CarlaWithin the Occupational Hygiene community, the risk assessment due to exposure to biological agents has received little attention compared to chemical agents. However, the impact of the current COVID-19 pandemic highlights the importance of raising awareness and prioritizing the prevention of work-related health effects caused by biological agents. However, tools for inventorying hazards, performing risk assessments, implementing control measures, and anchoring the results are rare. With the COVID-19 pandemic in mind, biological agents are often only referred to as infectious diseases. However, both infectious and non-infectious microorganisms may cause health effects. Workers in various sectors, such as healthcare and veterinary services, agriculture, waste, and wastewater management, and laboratories may be exposed through aerosols or contact with infected persons or materials that are contaminated by microorganisms. Furthermore, the sensitizing and toxic effects of biological agents are not considered when they are classified into biological agent risk groups. The sensitizing biological agents include fungi and certain bacteria (including thermophile actinomycetes). Toxic effects can be caused by metabolic products and cellular constituents of biological agents. Increased focus on biological exposures and health effects is therefore needed in order to improve the risk assessment for biological agents. The evaluation of workplace bioaerosol exposure risk is complex, considering the great diversity of bioaerosols and their effects, the limitations of the measurement methods available, and the lack of occupational exposure limits. In this symposium we present the concept of a tiered biological agents risk assessment, starting with a qualitative and ending with a quantitative approach.
- Characterization of 24 years of amputations performed in Portugal (2000-2023)Publication . Matos, José Pedro; Matos, Mariana; Ramos, M. Rosário; Ricardo, Diogo; Carolino, ElisabeteAmputation, whether surgical or traumatic, entails the loss of a body segment due to irreparable injury caused by trauma, vascular conditions, or other pathologies. Among individuals with diabetes, amputation remains one of the most feared and recognized outcomes. However, early diagnosis and timely intervention could prevent approximately 50% of diabetes-related amputations and ulcerations. This retrospective observational cross-sectional study draws on data from the Hospital Morbidity Database (BDGDH), provided by the Central Administration of the Health System (ACSS) under the Ministry of Health. This study focuses on amputations in diabetic patients in Portugal, particularly from 2000 to 2023. It aims to update statistical results and projections using current data to inform health planning and optimize resource allocation. The research uses data from the Hospital Morbidity Database, analysing factors such as year, age group, gender, and diagnosis codes. Poisson regression and Negative Binomial models were applied to estimate annual amputation rates and forecast future trends. The findings will help compare national trends with international standards, guiding public health policies and supporting prevention and early diagnosis programs to reduce the socio-economic impact of amputations.
- Comparação da coloração de H&E com hematoxilina de Harris: protocolo convencional vs. progressivoPublication . Bernardino, Cátia; Trindade, Giulia; Caramelo, Rita; Palma, João; Borges-Ferro, AHaematoxylin and Eosin (H&E) staining is an essential technique used for the microscopic visualization of cytohistological structures. This method commonly applies Harris haematoxylin (HH) to stain basophilic structures, particularly cell nuclei. Generally, a regressive staining protocol is employed, which includes hydrochloric alcohol as a differentiator to remove excess stain. Alternatively, a progressive protocol can be used, which does not require differentiation, making it typically faster and less resource-intensive. This study aimed to determine the most efficient method for HH staining in H&E by comparing both regressive and progressive approaches. Thirty-two non-neoplastic human tissue samples were stained using the regressive protocol, as well as three variations of the progressive protocol with HH incubation times of 3, 4, and 5 minutes. Two specialists assessed the following parameters using a weighted scoring scale from 0 to 100 points: a) morphological preservation, b) intensity of nuclear staining, c) intensity of cytoplasmic staining, d) nuclear detail, and e) non-specific staining. The average scores were 94.06 ± 8.32 for the regressive protocol and 89.84 ± 10.00, 93.12 ± 8.27, and 92.13 ± 7.04 for the progressive protocols with incubation times of 3, 4, and 5 minutes, respectively. To evaluate the impact of the different protocols on staining quality, a one-way analysis of variance (ANOVA) was performed, revealing no significant differences (F(3, 124) = 1.463, p = 0.228); Tukey's post-hoc test supported this finding. These results suggest that the choice of protocol does not significantly affect staining quality, implying that other factors may contribute to variability in performance. Notably, the 3-minute progressive protocol emerged as the most efficient option, as it reduced staining time and eliminated the need for a differentiating agent while achieving results comparable to those of the regressive method. Future research should explore additional factors influencing staining quality, such as haematoxylin oxidation, and consider replicating the study with a more diverse sample set, including neoplastic tissues.
- Comparison of the serum whole molecular composition with the serum metabolome to acquire the pathophysiological statePublication . Correia, Inês; Henrique Fonseca, Tiago Alexandre; Pataco, Jéssica; Oliveira, Mafalda; Caldeira, Viviana; Domingues, N.; Von Rekowski, Cristiana; Araújo, Rúben Alexandre Dinis; Bento, Luís; Calado, Cecília; Domingues, Nuno; Tomar, Rajesh Singh; Mahamud, TosapornOmics Sciences serve as an essential tool to advance precision medicine. Since conventional omics sciences rely on laborious, complex and time-consuming analytical processes, this study evaluated whether the serum molecular fingerprint, captured by FTIR spectroscopy, could predict mortality risk in critically ill patients. Both the whole serum and the serum metabolome (i.e., serum after removal of macromolecules) were analyzed. PCA-LDA models demonstrated strong performance in predicting patients’ pathophysiological state. A significantly more accurate model for predicting the patients’ pathophysiological state was achieved using the serum metabolome (94%) compared to the whole serum (81%). This is consistent with metabolomics, which provides a more direct view of the systems’ functionality. These promising results highlight the importance of FTIR spectroscopy analysis of the serum metabolome, offering a rapid, cost-effective, and high-throughput method for assessing patients' pathophysiological state.
- O contributo do ortoptista na equipa de saúde em Cabo Verde: cuidados de saúde terciáriosPublication . Fernandes, NádiaDeficiência visual: a) cegueira: para casos de perda total de visão ou quando o indivíduo tem de confiar predominantemente nas habilidades de substituição de visão; b) baixa visão: para casos de menor grau de perda de visão, em que o indivíduo pode melhorar o seu desempenho visual através de ajudas. O indivíduo com baixa visão é aquele que apresenta diminuição do funcionamento visual, mesmo após tratamento e/ ou correção óptica convencional, e tem uma acuidade visual menor que 0.33 a percepção luminosa, ou um campo visual inferior a 10º do seu ponto de fixação, mas que utiliza ou é potencialmente capaz de utilizar a visão para o planeamento e/ou execução de uma tarefa em que a visão é essencial.
- Desafios e competências para os bibliotecários do Politécnico de LisboaPublication . Marques, Luísa Maria Lousã; Antunes, Maria Luz; Teófilo, RuiQuais são as linhas orientadoras para as Bibliotecas do Ensino Superior do século XXI? Quais são as exigências atuais que se colocam aos Bibliotecários? Como a está a tecnologia a transformar o papel do bibliotecário? Como está a ser incorporada a IA nas Bibliotecas do IPL? IA como ameaça ou aliada? Como prepararmo-nos para este novo cenário? Que competências serão essenciais no futuro? Como garantir que a IA seja inclusiva e ética nas bibliotecas?