Browsing by resource type "conference paper"
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- Angioplastia pulmonar e Riociguat na hipertensão pulmonar tromboembólica crónica: o Deus ou o Diabo?Publication . Araújo, Patrícia C.; Pereira, E.; Coelho, André
- Biological agents risk assessment: how to close the gap between science, policy making and occupational health and safety practice?Publication . Colomo, Carlota Alejandre; Heussen, Henri; Van der Haar, Rudolf; Marchand, Geneviève; Madsen, Anne Mette; Viegas, CarlaWithin the Occupational Hygiene community, the risk assessment due to exposure to biological agents has received little attention compared to chemical agents. However, the impact of the current COVID-19 pandemic highlights the importance of raising awareness and prioritizing the prevention of work-related health effects caused by biological agents. However, tools for inventorying hazards, performing risk assessments, implementing control measures, and anchoring the results are rare. With the COVID-19 pandemic in mind, biological agents are often only referred to as infectious diseases. However, both infectious and non-infectious microorganisms may cause health effects. Workers in various sectors, such as healthcare and veterinary services, agriculture, waste, and wastewater management, and laboratories may be exposed through aerosols or contact with infected persons or materials that are contaminated by microorganisms. Furthermore, the sensitizing and toxic effects of biological agents are not considered when they are classified into biological agent risk groups. The sensitizing biological agents include fungi and certain bacteria (including thermophile actinomycetes). Toxic effects can be caused by metabolic products and cellular constituents of biological agents. Increased focus on biological exposures and health effects is therefore needed in order to improve the risk assessment for biological agents. The evaluation of workplace bioaerosol exposure risk is complex, considering the great diversity of bioaerosols and their effects, the limitations of the measurement methods available, and the lack of occupational exposure limits. In this symposium we present the concept of a tiered biological agents risk assessment, starting with a qualitative and ending with a quantitative approach.
- Comparação da coloração de H&E com hematoxilina de Harris: protocolo convencional vs. progressivoPublication . Bernardino, Cátia; Trindade, Giulia; Caramelo, Rita; Palma, João; Borges-Ferro, AHaematoxylin and Eosin (H&E) staining is an essential technique used for the microscopic visualization of cytohistological structures. This method commonly applies Harris haematoxylin (HH) to stain basophilic structures, particularly cell nuclei. Generally, a regressive staining protocol is employed, which includes hydrochloric alcohol as a differentiator to remove excess stain. Alternatively, a progressive protocol can be used, which does not require differentiation, making it typically faster and less resource-intensive. This study aimed to determine the most efficient method for HH staining in H&E by comparing both regressive and progressive approaches. Thirty-two non-neoplastic human tissue samples were stained using the regressive protocol, as well as three variations of the progressive protocol with HH incubation times of 3, 4, and 5 minutes. Two specialists assessed the following parameters using a weighted scoring scale from 0 to 100 points: a) morphological preservation, b) intensity of nuclear staining, c) intensity of cytoplasmic staining, d) nuclear detail, and e) non-specific staining. The average scores were 94.06 ± 8.32 for the regressive protocol and 89.84 ± 10.00, 93.12 ± 8.27, and 92.13 ± 7.04 for the progressive protocols with incubation times of 3, 4, and 5 minutes, respectively. To evaluate the impact of the different protocols on staining quality, a one-way analysis of variance (ANOVA) was performed, revealing no significant differences (F(3, 124) = 1.463, p = 0.228); Tukey's post-hoc test supported this finding. These results suggest that the choice of protocol does not significantly affect staining quality, implying that other factors may contribute to variability in performance. Notably, the 3-minute progressive protocol emerged as the most efficient option, as it reduced staining time and eliminated the need for a differentiating agent while achieving results comparable to those of the regressive method. Future research should explore additional factors influencing staining quality, such as haematoxylin oxidation, and consider replicating the study with a more diverse sample set, including neoplastic tissues.
- Comparison of the serum whole molecular composition with the serum metabolome to acquire the pathophysiological statePublication . Correia, Inês; Henrique Fonseca, Tiago Alexandre; Pataco, Jéssica; Oliveira, Mafalda; Caldeira, Viviana; Domingues, N.; Von Rekowski, Cristiana; Araújo, Rúben Alexandre Dinis; Bento, Luís; Calado, Cecília; Domingues, Nuno; Tomar, Rajesh Singh; Mahamud, TosapornOmics Sciences serve as an essential tool to advance precision medicine. Since conventional omics sciences rely on laborious, complex and time-consuming analytical processes, this study evaluated whether the serum molecular fingerprint, captured by FTIR spectroscopy, could predict mortality risk in critically ill patients. Both the whole serum and the serum metabolome (i.e., serum after removal of macromolecules) were analyzed. PCA-LDA models demonstrated strong performance in predicting patients’ pathophysiological state. A significantly more accurate model for predicting the patients’ pathophysiological state was achieved using the serum metabolome (94%) compared to the whole serum (81%). This is consistent with metabolomics, which provides a more direct view of the systems’ functionality. These promising results highlight the importance of FTIR spectroscopy analysis of the serum metabolome, offering a rapid, cost-effective, and high-throughput method for assessing patients' pathophysiological state.
- O contributo do ortoptista na equipa de saúde em Cabo Verde: cuidados de saúde terciáriosPublication . Fernandes, NádiaDeficiência visual: a) cegueira: para casos de perda total de visão ou quando o indivíduo tem de confiar predominantemente nas habilidades de substituição de visão; b) baixa visão: para casos de menor grau de perda de visão, em que o indivíduo pode melhorar o seu desempenho visual através de ajudas. O indivíduo com baixa visão é aquele que apresenta diminuição do funcionamento visual, mesmo após tratamento e/ ou correção óptica convencional, e tem uma acuidade visual menor que 0.33 a percepção luminosa, ou um campo visual inferior a 10º do seu ponto de fixação, mas que utiliza ou é potencialmente capaz de utilizar a visão para o planeamento e/ou execução de uma tarefa em que a visão é essencial.
- Desafios e competências para os bibliotecários do Politécnico de LisboaPublication . Marques, Luísa Maria Lousã; Antunes, Maria Luz; Teófilo, RuiQuais são as linhas orientadoras para as Bibliotecas do Ensino Superior do século XXI? Quais são as exigências atuais que se colocam aos Bibliotecários? Como a está a tecnologia a transformar o papel do bibliotecário? Como está a ser incorporada a IA nas Bibliotecas do IPL? IA como ameaça ou aliada? Como prepararmo-nos para este novo cenário? Que competências serão essenciais no futuro? Como garantir que a IA seja inclusiva e ética nas bibliotecas?
- Design of a Cardiopulmonary antenna for vital signs monitoring robust to different subjectsPublication . Cardoso, João; Pinho, Pedro; Gouveia, Carolina; Albuquerque, DanielWith the advancement of wireless diagnosis and treatment technologies, antennas deployed close to the human body are now widely used. The use of on-body antennas, along with other technologies, presents itself as an innovative method for detecting and monitoring vital signs. These antennas can be attached directly on the body or on clothes, making it comfortable to use and less invasive when compared to conventional methods, allowing at-home monitoring of elderly patients or high risk workers with a single antenna. In this paper, a robust high bandwidth patch antenna was developed to operate in the dedicated Industrial, Scientific and Medical frequency band, namely at 2.45 GHz, capable of monitoring vital signs in any subject. This work presents the design and results of a robust cardiopulmonary antenna, to be further used to monitor the respiratory rate of five different subjects, each one with different physiognomy.
- ESS design and management considering solar PV to fed off-grid EV chargerPublication . Santos, Diogo; Fonte, Pedro M; Pereira, Rita Marcos Fontes Murta; Barata, Filipe; Almeida, Paulo; Cordeiro, Armando; Luís, Ricardo Jorge Ferreira; Fernao Pires, VitorThe increase of electric vehicles creates several challenges to the electric grid, mainly in those with weak power or off-grid. DC microgrids are becoming more and more important in the context of renewable energy sources, where solar PV systems are dominant. In this paper is proposed the design of a DC system to charge electric vehicles using PV generation and a battery storage system. A single DC-DC converter is used to operate the solar PV array with maximum power point tracking method and controls power flow from PV to storage battery and to the EV, operating as DC EV charger. The operation under various loading conditions is discussed. The performance of the proposed solution was simulated using MATLAB/Simulink software.
- ExotropiasPublication . Lino, PedroEstrabismo - Síndroma oculomotora com duas componentes motora e sensorial. Na componente motora um dos olhos encontra se desviado, estando numa posição anómala face ao outro, dito dominante. Na componente sensorial existe alterações da visão binocular de modo a que as imagens não se formam em pontos retinianos correspondentes o que leva ao desenvolvimento de fenómenos sensoriais subsequentes e/ou compensatórios. Exotropia - Desvio temporal dos eixos visuais. Exotropia intermitente X(T): representa a forma mais comum de exodesvios. Prevalência estimada 60 em crianças com desenvolvimento normal. Exotropia constante: desvio divergente permanente dos eixos visuais XT congénita, XT secundária (sensorial), XT secundária a uma X(T) descompensada.
- De facto or de jure harmonisation: how much dis(harmonised) are the entities in an IFRS environment?Publication . Albuquerque, Fábio; Santos, PaulaThis paper uses exploratory analysis to seek evidence of accounting practices in a harmonized environment that mitigates the comparability of financial reporting by selecting an exemplary topic from different cases. The topics include the treatment given by entities to those cases not prescribed in the standards, but traditionally used by entities, cases prescribed by standards, but in a way that is not specific or clear enough, and, finally, cases where standards allow alternative accounting treatments. The consolidated reports and accounts of the entities included in the main Euronext Lisbon index for the years 2019 and 2020 were assessed. It was found that the accounting practices adopted by the entities are diverse, with different implications within the options that are reflected in the recognition and presentation of expenses and incomes. This type of research allows broadening the discussion around the implementation of effective measures to reduce the subjectivity associated with the adoption and application of standards to reach higher levels of de facto harmonisation or convergence. It is expected that the proposed analysis can contribute to drawing the attention of standard-setters and regulators of financial reporting to the potential constraints associated with the high flexibility of, or gaps in, International Financial Reporting Standards.
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