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Advisor(s)
Abstract(s)
Background/Objectives: The COVID-19 pandemic has revolutionized vaccine production and compelled a massive global vaccination campaign. This study aimed to estimate the positivity and levels of SARS-CoV-2 IgG antibodies acquired due to vaccination and infection in the academic population of a Portuguese university. Methods: Blood samples were collected and analyzed using the ELISA methodology, and statistical analysis was performed. Results: A total of 529 volunteers with at least one dose of the vaccine were enrolled in this study. Individuals without a prior COVID-19 diagnosis were divided into two groups: 350, who received a full vaccination, and 114, who received a full vaccination and a booster dose of the same vaccine (81) and mixed vaccines (33). Regarding the individuals who reported a prior SARS-CoV-2 infection, 31 received a full vaccination, and 34 received only one vaccination dose. Data analysis showed a higher level of IgG against SARS-CoV-2 in younger, female individuals who received the Moderna vaccine, with recent post-vaccine administration, a mixed booster dose, and prior SARS-CoV-2 infection. Conclusions: Assessing vaccination’s effectiveness and group immunity is crucial for pandemic management, particularly in academic environments with high individual mobility, to define groups at risk and redirect infection control strategies.
Description
This work was supported by Project COVID management and acquired immunity assessment in the IPL community (COVIDVax_IPL) funded by Instituto Politécnico de Lisboa (IPL). H&TRC authors gratefully acknowledge the FCT/MCTES UIDP/05608/2020, and UIDB/05608/2020).
Keywords
SARS-CoV-2 Immunity Vaccines Academic community Immunological variables FCT_UIDP/05608/2020 FCT_UIDB/05608/2020
Citation
Oliveira K, Almeida A, Silva C, Brito M, Ribeiro E. SARS-CoV-2 immunization index in the academic community: a retrospective post-vaccination study. Infect Dis Rep. 2024;16(6):1084-97.