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SARS-CoV-2 immunization index in the academic community: a retrospective post-vaccination study

2024-11Journal article Open access
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dc.contributor.authorOliveira, Ketlyn
dc.contributor.authorAlmeida, Ana
dc.contributor.authorSilva, Carina
dc.contributor.authorBrito, Miguel
dc.contributor.authorRibeiro, Edna
dc.date.accessioned2024-12-11T09:55:25Z
dc.date.available2024-12-11T09:55:25Z
dc.date.issued2024-11
dc.descriptionThis work was supported by Project COVID management and acquired immunity assessment in the IPL community (COVIDVax_IPL) funded by Instituto Politécnico de Lisboa (IPL). H&TRC authors gratefully acknowledge the FCT/MCTES UIDP/05608/2020, and UIDB/05608/2020).pt_PT
dc.description.abstractBackground/Objectives: The COVID-19 pandemic has revolutionized vaccine production and compelled a massive global vaccination campaign. This study aimed to estimate the positivity and levels of SARS-CoV-2 IgG antibodies acquired due to vaccination and infection in the academic population of a Portuguese university. Methods: Blood samples were collected and analyzed using the ELISA methodology, and statistical analysis was performed. Results: A total of 529 volunteers with at least one dose of the vaccine were enrolled in this study. Individuals without a prior COVID-19 diagnosis were divided into two groups: 350, who received a full vaccination, and 114, who received a full vaccination and a booster dose of the same vaccine (81) and mixed vaccines (33). Regarding the individuals who reported a prior SARS-CoV-2 infection, 31 received a full vaccination, and 34 received only one vaccination dose. Data analysis showed a higher level of IgG against SARS-CoV-2 in younger, female individuals who received the Moderna vaccine, with recent post-vaccine administration, a mixed booster dose, and prior SARS-CoV-2 infection. Conclusions: Assessing vaccination’s effectiveness and group immunity is crucial for pandemic management, particularly in academic environments with high individual mobility, to define groups at risk and redirect infection control strategies.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationOliveira K, Almeida A, Silva C, Brito M, Ribeiro E. SARS-CoV-2 immunization index in the academic community: a retrospective post-vaccination study. Infect Dis Rep. 2024;16(6):1084-97.pt_PT
dc.identifier.doi10.3390/idr16060088pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.21/18006
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.relation.publisherversionhttps://www.mdpi.com/2036-7449/16/6/88pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectSARS-CoV-2pt_PT
dc.subjectImmunitypt_PT
dc.subjectVaccinespt_PT
dc.subjectAcademic communitypt_PT
dc.subjectImmunological variablespt_PT
dc.subjectFCT_UIDP/05608/2020pt_PT
dc.subjectFCT_UIDB/05608/2020pt_PT
dc.titleSARS-CoV-2 immunization index in the academic community: a retrospective post-vaccination studypt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage1097pt_PT
oaire.citation.issue6pt_PT
oaire.citation.startPage1084pt_PT
oaire.citation.titleInfectious Disease Reportspt_PT
oaire.citation.volume16pt_PT
person.familyNameAlmeida
person.familyNameSilva
person.familyNameBrito
person.familyNameRibeiro
person.givenNameAna
person.givenNameCarina
person.givenNameMiguel
person.givenNameEdna
person.identifier2405257
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person.identifier.ciencia-id2411-5936-0820
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person.identifier.ciencia-idC414-CDF2-D35A
person.identifier.orcid0000-0003-4984-0759
person.identifier.orcid0000-0003-1021-7935
person.identifier.orcid0000-0001-6394-658X
person.identifier.orcid0000-0003-1316-7750
person.identifier.ridE-6523-2019
person.identifier.ridA-7970-2016
person.identifier.scopus-author-id57191899755
person.identifier.scopus-author-id55258764900
person.identifier.scopus-author-id35224551000
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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