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SARS-CoV-2 immunization in academic community: vaccination schemes efficiency

2025-03Book part Embargoed access
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datacite.subject.sdg03:Saúde de Qualidade
dc.contributor.authorAlmeida, Ana
dc.contributor.authorOliveira, Ketlyn
dc.contributor.authorRibeiro, Edna
dc.date.accessioned2025-04-07T11:39:07Z
dc.date.available2025-04-07T11:39:07Z
dc.date.issued2025-03
dc.descriptionThis work was supported by Project COVID management and acquired immunity assessment in the IPL community (COVIDVax_IPL) funded by Instituto Politécnico de Lisboa (IPL). H&TRC authors gratefully acknowledge the FCT/MCTES UIDP/05608/2020, and UIDB/05608/2020.
dc.description.abstractBackground: Severe acute respiratory syndrome coronavirus 2 immunoglobulin G (SARS-CoV-2-IgG) antibodies have been widely used to assist clinical diagnosis and occupational exposure risks. Objectives: This study aimed to estimate SARS-CoV-2 IgG levels acquired due to different vaccination schemes. Materials and methods: A retrospective study was performed on volunteers from the Instituto Politécnico de Lisboa. Blood samples were collected and analyzed through the ELISA methodology and a statistical analysis was conducted. Results: Among study participants, the percentage of women was higher than men, with an average age of 39.02 years. 88.5% of individuals had an mRNA vaccination versus 11.5% for a viral vector vaccination. Moderna vaccine had the highest IgG titer (9.62 index), while the lowest titer was 5.97 index, obtained by the Janssen vaccine. Data from individuals with the 2nd vaccine dose corresponded to the highest percentage of seropositive titers (62.6%). Regarding the time between vaccination and sample collection, 41.9% were collected over six months and 2.2% between 1 and 2 months. Discussion: Data demonstrated that the vaccine technology, the period between vaccination and collection, and cross-vaccination have a significant impact on SARS-CoV-2 IgG levels. In conclusion, future assessment of individual immune responses and group immunity is crucial for occupational exposure and public health.eng
dc.identifier.citationAlmeida A, Oliveira K, Ribeiro E. SARS-CoV-2 immunization in academic community: vaccination schemes efficiency. In: Baptista JS, Melo RB, Carneiro P, Castelo Branco J, Costa N, Duarte J, et al. Occupational and environmental safety and health VI: occupational risk assessment, management and case studies (Vol. I). Cham: Springer; 2025. p. 193-203.
dc.identifier.doi10.1007/978-3-031-82166-0_17
dc.identifier.isbn9783031821653
dc.identifier.isbn9783031821660
dc.identifier.issn2198-4182
dc.identifier.issn2198-4190
dc.identifier.urihttp://hdl.handle.net/10400.21/21773
dc.language.isoeng
dc.peerreviewedyes
dc.publisherSpringer Nature
dc.relation.hasversionhttps://link.springer.com/chapter/10.1007/978-3-031-82166-0_17
dc.relation.ispartofStudies in Systems, Decision and Control
dc.relation.ispartofOccupational and Environmental Safety and Health VI
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectSARS-CoV-2
dc.subjectVaccination schemes
dc.subjectIgG index
dc.subjectOccupational exposure
dc.subjectHigher education
dc.subjectPortugal
dc.subjectInstituto Politécnico de Lisboa
dc.subjectCOVIDVax_IPL
dc.subjectFCT_UIDP/05608/2020
dc.subjectFCT_UIDB/05608/2020
dc.titleSARS-CoV-2 immunization in academic community: vaccination schemes efficiencyeng
dc.typebook part
dspace.entity.typePublication
oaire.citation.endPage203
oaire.citation.startPage193
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyNameAlmeida
person.familyNameRibeiro
person.givenNameAna
person.givenNameEdna
person.identifier2405257
person.identifier.ciencia-id0116-985F-3D81
person.identifier.ciencia-idC414-CDF2-D35A
person.identifier.orcid0000-0003-4984-0759
person.identifier.orcid0000-0003-1316-7750
person.identifier.ridE-6523-2019
person.identifier.scopus-author-id57191899755
relation.isAuthorOfPublication6adcdd33-b852-4e90-b4b0-551dfc0d8fb9
relation.isAuthorOfPublicationa571bf34-bcda-49ca-b5cb-4cdecbb3d9c7
relation.isAuthorOfPublication.latestForDiscovery6adcdd33-b852-4e90-b4b0-551dfc0d8fb9

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