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Nuno, Sérgio Loureiro

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  • Functional asymmetries after 6 months of ACL reconstruction: a cross‐sectional study
    Publication . Nuno, Sérgio Loureiro; Romero‐Morales, Carlos; López‐López, Daniel; Losa‐Iglesias, Marta Elena; Becerro‐de‐Bengoa‐Vallejo, Ricardo; Gómez‐Salgado, Juan; Guerra, João; Saavedra‐García, Miguel Ángel
    Functional tests commonly assess athletes' readiness to return to sports after knee surgery. Despite this, there are still more studies on clinical and patient-reported outcomes. The purpose of this study was to determine differences and combinations of various functional performances within and between athletes 6 months after anterior cruciate ligament (ACL) reconstruction (ACLR) for the first time (ACLR-I group), versus second ACL injury on the same knee (ACLR-II group), versus ACLR procedures on both legs (ACLR-III group). A total of 88 patients with ACLR performed single-leg hop (maximum forward distance hop, SLH; side hop > 40 cm in 30 s, SH), Functional Movement Screen (FMS), and dynamic postural balance (Y Balance Test - YBT). Data were recorded during return-to-sport testing (6 months post-surgery). For each variable, a mixed-model analysis of variance, with a between-subjects factor of group (primary ACL injury, recurrent ACL injury, and bilateral ACL injury) and a within-subjects factor of limb (involved, uninvolved), was conducted. Differences between the groups were found in different degrees of inter-limb asymmetry in the single-leg hop (p < 0.001) and side hop test (p < 0.02). There was a main effect of limb for the anterior and posteromedial YBT distances, and the single-leg hop and side hop test distances (p ≤ 0.04). For each variable, performance was worse for the involved limb compared to the uninvolved limb. Individuals after recurrent ACLR showed greater functional asymmetries at 6 months of treatment. Jumping tests detected greater performance deficits compared to YBT and FMS.
  • Perfusion, stance and plantar pressure asymmetries on the human foot in the absence of disease: a pilot study
    Publication . Rodrigues, Luis Monteiro; Nuno, Sérgio Loureiro; Granja, Tiago; Florindo, Margarida Esteves; Gregório, João; Atalaia, Tiago
    Physiological perfusion asymmetries in the lower limb are known, although poorly understood, as are asymmetries reported in plantar pressure and stance. This preliminary study aims to explore potential relationships between perfusion and pressure variables in humans. A convenience sample of eight healthy individuals (25.25 ± 5.37 years old) of both sexes, was selected. Chosen variables were perfusion, plantar pressure, and stance. Perfusion was measured in both feet by laser Doppler flowmetry (LDF) and polarized light spectroscopy (PSp), and plantar pressure and stance were obtained by a pressure plate. These were measured in baseline (Phase I) in repeated squatting (Phase II), and in recovery (Phase III). A 95% confidence interval was adopted. Intraindividual significant perfusion asymmetries between both feet were detected by LDF in Phase I. These disappeared in Phase II and returned in Phase III. PSp did not detect any asymmetries. Plantar pressure was also asymmetric and differently distributed along both feet with no statistical significance except in the hindfoot. Significant correlations were found between BMI and mean Plantar Pressure in Phase I and Phase III, and an inverse correlation between LDF perfusion and Plantar Pressure in Phase I. These results seem to suggest an interesting direction for the exploration and study of these asymmetries in the absence of disease.
  • Studying the impact of different body positioning, squatting, and unipodal flexion on perfusion in the lower limb: an exploratory approach complemented with optical spectroscopy (TiVi)
    Publication . Nuno, Sérgio Loureiro; Florindo, Margarida; Silva, Henrique; Rodrigues, Luis Monteiro
    Body posture and movement seem to be responsible for multiple variations of microcirculation in the foot, although difficulties associated with measurement during movement have limited their characterization. This pilot study sought to explore a new non-invasive instrument based on polarized light spectroscopy – the TiVi system, under orthostatic and dynamic conditions. Five healthy participants (duly informed, 26.0 ± 6.5 years of age) of both genders were selected. The protocol involved sequential posture changes (orthostatic variation) and dynamic movements (squatting and unipodal flexion). Perfusion variations were evaluated in both feet by laser-Doppler flowmetry (LDF) and polarized spectroscopy (TiVi). Both systems revealed the same type of modification of these flow-related variables. The most pronounced changes were obtained with exercise, especially with squatting, which caused a marked increase in foot perfusion. Less dramatic but in the same direction, the increased perfusion with unipodal flexion was also observed in the contralateral limb. This study confirmed the interest in using the TiVi system in these domains, as well as the appropriateness of this experimental design to look deeper into the impact of lower limb movement on the functional dynamics of the foot.
  • Lower limb dynamic activity significantly reduces foot skin perfusion: exploring data with different optical sensors in age-grouped healthy adults
    Publication . Florindo, Margarida; Nuno, Sérgio Loureiro; Rodrigues, Luis Monteiro
    Introduction: The human lower limb is widely used as a model to study in vivo microcirculatory physiology and pathophysiology. It is a preferential target for critical comorbidities (overweight, diabetes, and peripheral vascular disease). Movement and activity are consistently regarded as beneficial, but the related adaptive physiology is still poorly understood. Our goal was to better identify the foot microcirculatory changes after a regular walking gait activity in healthy subjects of different ages. Methods: Twelve healthy participants of both sexes, with normal BMI and Ankle-Brachial Index, were selected and grouped according to age - group I (21.0 ± 1 y.o.) and group II (55.8 ± 3 y.o.). The protocol involved 2 phases of 5-min duration each - phase 1, a static standing position, and phase 2, 5-min walking with a comfortable pace on a pre-established circuit. Perfusion changes were assessed in the dorsal region of both feet before (baseline, phase 1) and after (phase 2) the gait period by noninvasive optical technologies - laser Doppler flowmetry (LDF), photoplethysmography, and polarized spectroscopy (PSp). Comparative statistics were performed with a 95% confidence level. Results: All instruments detected asymmetric nonsignificant perfusion between right and left feet during rest in all participants with values in females consistently lower than men. Older participants exhibited lower baseline values than the younger group. Gait evoked a perfusion reduction in all participants relative to phase 1 detected with all technologies, with statistically significant changes recorded with LDF (group I, p = 0.033, and group II, p = 0.028) and PSp (group II, p = 0.041). Furthermore, LDF revealed that gait significantly reduced perfusion velocity in the older group (p = 0.003). Corresponding changes in the younger group were present but discrete. Recovery to baseline levels was also slower in the older group. Discussion/Conclusions: Our results confirm that perfusion is age-dependent and demonstrate the clinical relevance of simple dynamic activities such as gait. This reduction of the dorsal foot perfusion occurs in-depth, being more pronounced with the movement intensity, suggesting a wide application potential in early diagnostics as for rehabilitation.
  • Impact of lymphedema on foot-health-related quality of life: a case-control investigation
    Publication . Monteiro, Ana Júlia; de Labra, Carmen; Losa-Iglesias, Marta Elena; Dias, Adriano; Becerro-de-Bengoa-Vallejo, Ricardo; Silva-Migueis, Helena; Nuno, Sérgio Loureiro; López-López, Daniel; Gómez-Salgado, Juan
    Objective: To evaluate the foot-health-related quality of life in individuals with versus without lower-limb lymphedema. Methods: A case-control study was carried out in an academic clinic in Lisbon, Portugal. Eighty participants (40 controls and 40 with lymphedema) were included in the study. The researchers examined sociodemographic and clinical data and foot-health-related quality of life in both groups. In the group with lymphedema, lower-limb lymphedema was also characterized. Results: Individuals with lower-limb lymphedema had significantly lower scores on all dimensions of the Foot Health Status Questionnaire in comparison with the control group. Conclusions: Individuals with lower-limb lymphedema appear to have a poorer foot-health-related quality of life than the general population.
  • Análise da influência da aplicação de kinesio tape na ativação muscular durante um passe de futsal
    Publication . Nuno, Sérgio Loureiro; Atalaia, Tiago; Rebelo, Pedro; Carolino, Elisabete; Vaz, João
    Introdução – O futsal é um desporto exigente, pelo que a aplicação de bandas de kinesio tape surge como uma vertente de intervenção a considerar. Objetivos – Analisar o efeito do kinesio tape na ativação e amplitude muscular do longo peroneal e tibial anterior na execução de um passe. Metodologia – Foram estudados 40 passes por cada situação definida (sem banda de kinesio tape e com banda para o tibial anterior e longo peroneal, aplicadas em separado), perfazendo um total de 120 comportamentos distintos. O gesto técnico foi realizado por atletas sem historial de lesão. Após avaliação do sinal eletromiográfico foram estudados os dois picos presentes. Resultados – Verificaram- se diferenças entre as três situações em estudo. A banda de kinesio tape não se revelou eficaz na antecipação e aumento de ativação muscular nas condições definidas no estudo. Discussão – O executante estabelece estratégias diferentes para responder a diferentes estados de estabilidade ao longo dessa mesma tarefa. Conclusão – A individualidade de cada comportamento técnico foi estudado e pela ausência de história anterior de lesão dos seus executantes e pelo gesto técnico proposto o estímulo das bandas de kinesio tape pode não ter sido suficiente para o aumento e pré-ativação muscular.
  • Assessing the predictive value of preoperative knee function tests and self-report scores in anterior cruciate ligament injury recovery
    Publication . Nuno, Sérgio Loureiro; Romero-Morales, Carlos; López-López, Daniel; Losa-Iglesias, Marta Elena; Becerro-de-Bengoa-Vallejo, Ricardo; Gómez-Salgado, Juan; Guerra, João; Saavedra-García, Miguel Ángel
    Background: The ability to identify patients with long-term poor outcomes using clinical and functional information is limited. Identifying prognostic factors to improve long-term outcomes after anterior cruciate ligament (ACL) injury can influence and inform targeted interventions for this population. Hypothesis: Preoperative functional tests and patient-reported outcome measures predict postoperative functional recovery and satisfaction in patients undergoing first-time ACL repair, second-time ACL repair on the same knee, and bilateral ACL repair. Study design: Quasi-experimental prospective study. Level of evidence: Level 3. Methods: A total of 88 patients with ACL reconstruction were included. Subjective knee scoring systems and functional performance tests were evaluated and analyzed for correlation with results. Results: The first-time ACL injury group had lower scores in the various self-report scales: Knee injury and Osteoarthritis Outcome Score (KOOS), Lysholm Rating Scale, International Knee Documentation Committee (IKDC), and Lower Extremity Functional Scale (LEFS). Conclusion: Reduction in self-reported knee function and Y balance test performance after ACL injury are predictive factors for recovery. Estimates exceeded clinically important thresholds. Those who had already undergone surgery had clinically better thresholds, highlighting the assessment of these measures when designing presurgical rehabilitation programs.