RCIPL
Repositório Institucional do Politécnico de Lisboa
Entradas recentes
Challenges and opportunities for statistics in Omics data analysis
Publication . Carrasquinha, Eunice; Sousa, Lisete; Silva, Carina; Gama-Carvalho, Margarida; Figueiredo, Andreia; Pinto, Francisco Rodrigues
Omics data, comprising a diverse array of high-throughput molecular datasets, present substantial statistical challenges due to their intrinsic heterogeneity and variability. Effectively distinguishing biologically meaningful variations from random noise requires the application and development of robust statistical approaches. Interdisciplinary collaboration plays a pivotal role in refining these methodologies and enhancing the understanding of intricate biological systems. This chapter reviews the importance of statistical methods in omics data analysis, highlighting the need for ongoing advancements to address key challenges, including experimental design, preprocessing, dimensionality reduction, statistical modeling of complex datasets, and the interpretation of results. The pursuit of improved reliability in biological insights creates opportunities for the development and refinement of advanced statistical methodologies.
Obesity rise plateaus in developed nations and accelerates in developing nations
Publication . Bin Zhou; Nowell H. Phelps; Agnese Galeazzi; Olivia N. O’Driscoll; James E. Bennett; Lakshya Jain; Ysé D’Ailhaud De Brisis; Ana Barradas-Pires; Fulvio Deo; Gretchen A. Stevens; Vasilis Kontis; Christopher J. Paciorek; Rodrigo M. Carrillo-Larco; Anu Mishra; Yefeng Fan; Andrea Rodriguez-Martinez; Vishwa Nath; Archie W. Rayner; Annalise Zouein; Natalie R. Evans; Jennifer L. Baker; Günther Fink; Maroje Sorić; Carlos A. Aguilar-Salinas; Ranjit Mohan Anjana; Zulfiqar A. Bhutta; Pascal Bovet; Goodarz Danaei; Kairat Davletov; Shubash Ganapathy; Edward W. Gregg; Nayu Ikeda; Andre Pascal Kengne; Young-Ho Khang; Kamlesh Khunti; Tiina Laatikainen; Avula Laxmaiah; Lee-Ling Lim; Hsien-Ho Lin; Jean Claude N. Mbanya; J. Jaime Miranda; Anja Schienkiewitz; Sylvain Sebert; Namuna Shrestha; Yi Song; Luis Adrián Soto-Mota; Gregor Starc; Limin Wang; Novie O. Younger-Coleman; Francesco Zaccardi; Julie Aarestrup; Leandra Abarca-Gómez; Mohsen Abbasi-Kangevari; Ziad A. Abdeen; Shynar Abdrakhmanova; Suhaila Abdul Ghaffar; Hanan F. Abdul Rahim; Zulfiya Abdurahmnova; Niveen M. Abu-Rmeileh; Jamila Abubakar Garba; Benjamin Acosta-Cazares; Ishag Adam; Marzena Adamczyk; Robert J. Adams; Seth Adu-Afarwuah; Wichai Aekplakorn; Tin Afifah; Kaosar Afsana; Shoaib Afzal; Imelda A. Agdeppa; Javad Aghazadeh-Attari; Åsa Ågren; Hassan Aguenaou; Charles Agyemang; Mohamad Hasnan Ahmad; Noor Ani Ahmad; Ali Ahmadi; Naser Ahmadi; Nastaran Ahmadi; Imran Ahmed; Soheir H. Ahmed; Wolfgang Ahrens; Gulmira Aitmurzaeva; Kamel Ajlouni; Dilorom Akhmedova; Nilufar Akhmedova; Nasser Al-Daghri; Sarah F. Al-Hamli; Hazzaa M. Al-Hazzaa; Halima Al-Hinai; Jawad A. Al-Lawati; Rajaa Al-Raddadi; Islam K. Al-Shami; Deena Al Asfoor; Huda M. Al Hourani; Nawal M. Al Qaoud; Monira Alarouj; Fadia AlBuhairan; Shahla AlDhukair; Maryam A. Aldwairji; Sílvia Alexius; Mohamed M. Ali; Mohammed K. Ali; Nazirah Alias; Anna V. Alieva; Abdullah Alkandari; Buthaina M. Alkhatib; Mar Alvarez-Pedrerol; Eman Aly; Deepak N. Amarapurkar; Parisa Amiri; John Amoah; Norbert Amougou; Philippe Amouyel; Atieh Amouzegar; Lars Bo Andersen; Sigmund A. Anderssen; Jonas S. Andersson; Odysseas Androutsos; Malick Anne; Alireza Ansari-Moghaddam; Elena Anufrieva; Hajer Aounallah-Skhiri; Joana Araújo; Inger Ariansen; Carmen Arias López; Tahir Aris; Raphael E. Arku; Nimmathota Arlappa; Enrique G. Artero; Krishna K. Aryal; Thor Aspelund; Felix K. Assah; Nega Assefa; Batyrbek Assembekov; Maria Cecília F. Assunção; Shiu Lun Au Yeung; May Soe Aung; Juha Auvinen; Mária Avdičová; Kishwar Azad; Ana Azevedo; Mohsen Azimi-Nezhad; Fereidoun Azizi; Bontha V. Babu; Flora Bacopoulou; Azli Baharudin; Suhad Bahijri; Borko Bajić; Izet Bajramovic; Marta Bakacs; Nagalla Balakrishna; Yulia Balanova; Mohamed Bamoshmoosh; Maciej Banach; José R. Banegas; Joanna Baran; Rafał Baran; Carlo M. Barbagallo; Valter Barbosa Filho; Alberto Barcelo; Maja Baretić; Amina Barkat; Joaquin Barnoya; Lena Barrera; Marta Barreto; Aluisio J. D. Barros; Mauro Virgílio Gomes Barros; Anna Bartosiewicz; Alicja Basiak-Rasała; Abdul Basit; Joao Luiz D. Bastos; Iqbal Bata; Anwar M. Batieha; Aline P. Batista; Rosangela L. Batista; Zhamilya Battakova; Susanne Bauer; Louise A. Baur; Pascal M. Bayauli; Robert Beaglehole; Silvia Bel-Serrat; Antonisamy Belavendra; María R. Beltran-Valls; Habiba Ben Romdhane; Theodora Benedek; Judith Benedics; Mikhail Benet; Gilda Estela Benitez Rolandi; Pedro J. Benito; Michaela Benzeval; Elling Bere; Nicolas Berger; Ingunn Holden Bergh; Yemane Berhane; Salim Berkinbayev; Antonio Bernabe-Ortiz; Gailute Bernotiene; Ximena Berrios Carrasola; Paula Berruezo; Heloísa Bettiol; Manfred E. Beutel; Augustin F. Beybey; Jorge Bezerra; Aroor Bhagyalaxmi; Sumit Bharadwaj; Santosh K. Bhargava; Hongsheng Bi; Yufang Bi; Daniel Bia; Katia Biasch; Elysée Claude Bika Lele; Mukharram M. Bikbov; Bihungum Bista; Dusko J. Bjelica; Anne A. Bjerregaard; Peter Bjerregaard; Espen Bjertness; Marius B. Bjertness; Cecilia Björkelund; Ieva Blauzde; Moran Blaychfeld Magnazi; Katia V. Bloch; Anneke Blokstra; Simona Bo; Martin Bobak; Lynne M. Boddy; Bernhard O. Boehm; Jose G. Boggia; Elena Bogova; Carlos P. Boissonnet; Stig E. Bojesen; Marialaura Bonaccio; Americo Bonanni; Vanina Bongard; Alice Bonilla-Vargas; Matthias Bopp; Elaine Borghi; Herman Borghs; Steve Botomba; Rupert Bourne; Khadichamo Boymatova; Francesca Bracone; Lien Braeckevelt; Lutgart Braeckman; Marjolijn C. E. Bragt; Tasanee Braithwaite; Imperia Brajkovich; Francesco Branca; Juergen Breckenkamp; João Breda; Hermann Brenner; Lizzy M. Brewster; Garry R. Brian; Yajaira Briceño; Lăcrămioara Brîndușe; Bettina Bringolf-Isler; Brito, Miguel; Sinead Brophy; Johannes Brug; Anna Bugge; Marta Buoncristiano; Genc Burazeri; Con Burns; Antonio Cabrera de León; Joseph Cacciottolo; Cristina Cadenas-Sanchez; Hui Cai; Roberta B. Caixeta; Tilema Cama; Christine Cameron; José Camolas; Francesco Campa; Günay Can; Ana Paula C. Cândido; Felicia Cañete; Mario V. Capanzana; Naděžda Čapková; Eduardo Capuano; Rocco Capuano; Vincenzo Capuano; Marloes Cardol; Viviane C. Cardoso; Axel C. Carlsson; Esteban Carmuega; Joana Carvalho; Deborah Carvalho Malta; José A. Casajús; Felipe F. Casanueva; Jose Castro-Piñero; Ertugrul Celikcan; Laura Censi; Chiara Cerletti; Marvin Cervantes‐Loaiza; Juraci A. Cesar; Parinya Chamnan; Snehalatha Chamukuttan; Angelique W. Chan; Queenie Chan; Fadi J. Charchar; Marie-Aline Charles; Himanshu K. Chaturvedi; Nish Chaturvedi; Norsyamlina Che Abdul Rahim; Fangfang Chen; Huashuai Chen; Long-Sheng Chen; Shuohua Chen; Zhengming Chen; Ching-Yu Cheng; Yiling J. Cheng; Leila Cheraghi; Bahman Cheraghian; Angela Chetrit; Ekaterina Chikova-Iscener; Mai J. M. Chinapaw; Arnaud Chiolero; Adela Chirita-Emandi; María-Dolores Chirlaque; Chean Lin Chong; Kaare Christensen; Diego G. 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Daneshpour; Rachel Dankner; Parasmani Dasgupta; Saeed Dastgiri; Luc Dauchet; Afonso de Almeida; Francisco de Assis Guedes de Vasconcelos; Maria Alice Altenburg de Assis; Guy De Backer; Dirk De Bacquer; Jaco De Bacquer; Jeroen de Bont; Luigi G. De Filippis; Patrícia de Fragas Hinnig; Stefaan De Henauw; Pilar De Miguel-Etayo; Jan-Walter De Neve; Paula Duarte de Oliveira; Luz Maria De Regil; David De Ridder; Karin De Ridder; Susanne R. de Rooij; Ana Carolina M. G. N. de Sá; Delphine De Smedt; Thomas V. de Souza; Marco A. de Valois Correia Júnior; George Dedoussis; Mohan Deepa; Alexander D. Deev; Vincent DeGennaro; Francis Delpeuch; Stefaan Demarest; Elaine Dennison; Katarzyna Dereń; Valérie Deschamps; Ruslan D. Devrishov; Meghnath Dhimal; Juvenal Soares Dias-da-Costa; Alejandro Diaz; Francisco Diez-Canseco; Zivka Dika; Shirin Djalalinia; Visnja Djordjic; Ha T. P. Do; Annette J. 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Matsha; Victor Matsudo; Giletta Matteo; Pallab K. Maulik; Christina Mavrogianni; Artur Mazur; Camille M. Mba; Shelly R. McFarlane; Stephen T. McGarvey; Keeley McGee; Martin McKee; Rachael M. McLean; Scott B. McLean; Breige A. McNulty; Sounnia Mediene Benchekor; Jurate Medzioniene; Kirsten Mehlig; Vrinda Mehra; Amir Houshang Mehrparvar; Jørgen Meisfjord; Christine Meisinger; Jesus D. Melgarejo; Marina Melkumova; Júlio B. Mello; Sofia Mendes; Fabián Méndez; Carlos O. Mendivil; Ana Maria B. Menezes; Geetha R. Menon; Gert B. M. Mensink; Maria Teresa Menzano; Indrapal I. Meshram; Diane T. Meto; Haakon E. Meyer; Jie Mi; Kim F. Michaelsen; Nathalie Michels; Kairit Mikkel; Jelena P. Milešević; Jody C. Miller; Olga Milushkina; Cláudia S. Minderico; G. K. Mini; Juan Francisco Miquel; Mohammad Reza Mirjalili; Daphne Mirkopoulou; Parvin Mirmiran; Masoud Mirzaei; Marjeta Mišigoj-Duraković; Antonio Mistretta; Veronica Mocanu; Ana Mocumbi; Pietro A. Modesti; Jobe Modou; Sahar Saeedi Moghaddam; Shukri F. Mohamed; Kazem Mohammad; Mohammad Reza Mohammadi; Zahra Mohammadi; Noushin Mohammadifard; Viswanathan Mohan; Sherina Mohd Sidik; Muhammad Fadhli Mohd Yusoff; Iraj Mohebbi; Diego Moliner Urdiales; Line T. Møllehave; Niels C. Møller; Dénes Molnár; Amirabbas Momenan; Charles K. Mondo; Rafael Monge-Rojas; Michele M. Monroy-Valle; Roger A. Montenegro Mendoza; Eric Monterrubio-Flores; Kotsedi Daniel K. Monyeki; Jin Soo Moon; Mahmood Moosazadeh; Hermine T. Mopa; Farhad Moradpour; Leila B. Moreira; Alain Morejon; Luis A. Moreno; Francis Morey; Karen Morgan; Suzanne N. Morin; Erik Lykke Mortensen; George Moschonis; Alireza Moslem; Mildrey Mosquera; Malgorzata Mossakowska; Aya Mostafa; Seyed-Ali Mostafavi; Anabela Mota-Pinto; Eugen Mota; Jorge Mota; Maria Mota; Mohammad Esmaeel Motlagh; Jorge Motta; Robert Moumakwa; Marcos André Moura-dos-Santos; Yeva Movsesyan; Malay K. Mridha; Kelias P. Msyamboza; Alicia Mtijasevich; Thet Thet Mu; Magdalena Muc; Florian Muca; Boban Mugoša; Maria L. Muiesan; Martina Müller-Nurasyid; Patricia B. Munroe; Adrià Muntaner-Mas; Thomas Münzel; Molly M. Murphy; Celine Murrin; Jaakko Mursu; Elaine M. Murtagh; Kamarul Imran Musa; Sanja Musić Milanović; Vera Musil; Geofrey Musinguzi; Muel Telo M. C. Muyer; Iraj Nabipour; Gabriele Nagel; Farid Najafi; Harunobu Nakamura; Hanna Nalecz; Jana Námešná; Ei Ei K. Nang; Vinay B. Nangia; Martin Nankap; Sameer Narake; K. M. Venkat Narayan; Paola Nardone; Take Naseri; Tim Nawrot; William A. Neal; Nareemarn Neelapaichit; Mayssam Nehme; Azim Nejatizadeh; Ilona Nenko; Martin Neovius; Flavio Nervi; Olena Nesterova; Dinesh Neupane; Tze Pin Ng; Chung T. Nguyen; Nguyen D. Nguyen; Quang Ngoc Nguyen; Michael Y. Ni; Rodica Nicolescu; Peng Nie; Ramfis E. Nieto-Martínez; Yury P. Nikitin; Guang Ning; Toshiharu Ninomiya; Nobuo Nishi; Sania Nishtar; Marianna Noale; Oscar A. Noboa; Helena Nogueira; Maria Nordendahl; Børge G. Nordestgaard; Kevin I. Norton; Davide Noto; Natalia Nowak-Szczepanska; Mohannad Al Nsour; Irfan Nuhoğlu; Eha Nurk; Fred Nuwaha; Moffat Nyirenda; Terence W. O’Neill; Dermot O’Reilly; Galina Obreja; Caleb Ochimana; Angélica M. Ochoa-Avilés; Eiji Oda; Augustine N. Odili; Kyungwon Oh; Kumiko Ohara; Claes Ohlsson; Ryutaro Ohtsuka; Örn Olafsson; Brian Oldenburg; Maria Teresa A. Olinto; Isabel O. Oliveira; Mohd Azahadi Omar; Saeed M. Omar; Altan Onat; Sok King Ong; N. Charlotte Onland-Moret; Lariane M. Ono; Obinna Onodugo; Pedro Ordunez; Rui Ornelas; Francisco B. Ortega; Ana P. Ortiz; Pedro J. Ortiz; Merete Osler; Clive Osmond; Sergej M. Ostojic; Afshin Ostovar; Johanna A. Otero; Charlotte B. Ottendahl; Akaninyene Otu; Kim Overvad; Ellis Owusu-Dabo; Adetoyeje Y. Oyeyemi; Adewale L. Oyeyemi; Fred Michel Paccaud; Cristina P. Padez; Ioannis Pagkalos; Marat Pahimov; Elena Pahomova; Karina Mary de Paiva; Andrzej Pająk; Natalja Pajula; Alberto Palloni; Luigi Palmieri; Demosthenes Panagiotakos; Songhomitra Panda-Jonas; Arvind Pandey; Zengchang Pang; Francesco Panza; Antonio Paoli; Mariela Paoli; Sousana K. Papadopoulou; Dimitrios Papandreou; Rossina G. Pareja; Suvi Parikka; Soon-Woo Park; Suyeon Park; Winsome R. Parnell; Mahboubeh Parsaeian; Ionela M. Pascanu; Patrick Pasquet; Chona F. Patalen; Roengrudee Patanavanich; Nikhil D. Patel; Marcos Pattussi; Halyna Pavlyshyn; Raimund Pechlaner; Ivan Pećin; Dorthe C. Pedersen; Mangesh S. Pednekar; João M. Pedro; Ana B. Peinado; Sergio Viana Peixoto; Markku Peltonen; Guillem Pera; Alexandre C. Pereira; Marco A. Peres; Napoleon Perez-Farinos; Agustín Perez-Londoño; Cynthia M. Pérez; Markus Perola; Valentina Peterkova; Annette Peters; Janina Petkeviciene; Ausra Petrauskiene; Olga Petrovna Kovtun; Emanuela Pettenuzzo; Niloofar Peykari; Norbert Pfeiffer; Son Thai Pham; Felix P. Phiri; Rafael N. Pichardo; Preux Pierre-Marie; Iris Pigeot; Hynek Pikhart; Aida Pilav; Pavel Piler; Lorenza Pilotto; Francesco Pistelli; Freda Pitakaka; Aleksandra Piwonska; Andreia N. Pizarro; Pedro Plans-Rubió; Alina G. Platonova; Bee Koon Poh; Hermann Pohlabeln; Raluca M. Pop; Barry M. Popkin; Stevo R. Popovic; Miquel Porta; Georg Posch; Anil Poudyal; Dimitrios Poulimeneas; Hamed Pouraram; Farhad Pourfarzi; Akram Pourshams; Hossein Poustchi; Dorairaj Prabhakaran; Rajendra Pradeepa; Andrew Prentice; Alison J. Price; Jacqueline F. Price; Antonio Prista; Rui Providencia; Jardena J. Puder; Iveta Pudule; Soile Puhakka; Maria Puiu; Margus Punab; Muhammed S. Qadir; Radwan F. Qasrawi; Qing Qiao; Mostafa Qorbani; Anna Quialheiro; Hedley K. Quintana; Pedro J. Quiroga-Padilla; Tran Quoc Bao; Stefan Rach; Maria-Victoria Racu; Ivana Radic; Ricardas Radisauskas; Salar Rahimikazerooni; Mahfuzar Rahman; Mahmudur Rahman; Olli Raitakari; Manu Raj; Tamerlan Rajabov; Sherali Rakhmatulloev; Ivo Rakovac; Sudha Ramachandra Rao; Ambady Ramachandran; Otim P. C. Ramadan; Virgílio V. Ramires; Manuel Ramirez-Zea; Jacqueline Ramke; Elisabete Ramos; Rafel Ramos; Lekhraj Rampal; Sanjay Rampal; Sheena E. Ramsay; João F. L. B. Rangel Junior; Lalka S. Rangelova; Harish Ranjani; Ravindra P. Rannan-Eliya; João F. Raposo; Patricia Rarau; Vayia Rarra; Ramon A. Rascon-Pacheco; Mohammad-Mahdi Rashidi; Cassiano Ricardo Rech; Cristina Recuero Carretero; Josep Redon; Valéria Regecová; Jane D. P. Renner; Judit A. Repasy; Cézane P. Reuter; Luis Revilla; Andrew Reynolds; Negar Rezaei; Abbas Rezaianzadeh; Yeunsook Rho; Lourdes Ribas-Barba; Robespierre Ribeiro; Rogério T. Ribeiro; Elio Riboli; Fernando Rigo; Attilio Rigotti; Leanne M. Riley; Natascia Rinaldo; Tobias F. Rinke de Wit; Ulf Risérus; Ana I. Rito; Raphael M. Ritti-Dias; Juan A. Rivera; Reina G. Roa; Romana Roccaldo; Daniela Rodrigues; Fernando Rodríguez-Artalejo; Manuel A. Rodríguez-Pérez; María del Cristo Rodriguez-Perez; Laura A. Rodríguez-Villamizar; Andrea Y. Rodríguez; Ulla Roggenbuck; Peter Rohloff; Fabian Rohner; Rosalba Rojas-Martinez; Gemma Rojo-Martínez; Nipa Rojroongwasinkul; Almudena Rollán Gordo; Dora Romaguera; Elisabetta L. Romeo; Gil B. Rosa; Rafaela V. Rosario; Annika Rosengren; Ian Rouse; Vanessa Rouzier; Joel G. R. Roy; Maira Ruano Estrada; Maira H. Ruano; Adolfo Rubinstein; Frank J. Rühli; Jean-Bernard Ruidavets; Blanca Sandra Ruiz-Betancourt; Maria Ruiz-Castell; Emma Ruiz Moreno; Iuliia A. Rusakova; Wojciech Rusek; Kenisha Russell Jonsson; Paola Russo; Petra Rust; Marcin Rutkowski; Katri Sääksjärvi; Marge Saamel; Crizian G. Saar; Charumathi Sabanayagam; Kalpana Sabapathy; Hamideh Sabbaghi; Shaun Sabico; Harshpal S. Sachdev; Alireza Sadjadi; Ali Reza Safarpour; Sare Safi; Mohammad Hossien Saghi; Olfa Saidi; Calogero Saieva; Satoko Sakata; Nader Saki; Sanja Šalaj; Benoit Salanave; Eduardo Salazar Martinez; Akkumis Salkhanova; Diego Salmerón; Veikko Salomaa; Jukka T. Salonen; Massimo Salvetti; Margarita Samoutian; Jose Sánchez-Abanto; Guillermo Sanchez-Delgado; Mairena Sánchez-López; Joaquin Sanchis-Moysi; Susana Sans; Loreto Santa-Marina; Ethel Santacruz Lezcano; Diana A. Santos; Ina S. Santos; Lèlita C. Santos; Maria Paula Santos; Osvaldo Santos; Palmira Santos; Rute Santos; Tamara R. Santos; Vonthanak Saphonn; Jouko L. Saramies; Luis B. Sardinha; Nizal Sarrafzadegan; Yoko Sato; Kai-Uwe Saum; Stefan Savin; Savvas Savva; Mathilde Savy; Norie Sawada; Mariana Sbaraini; Marcia Scazufca; Beatriz D. Schaan; Angelika Schaffrath Rosario; Herman Schargrodsky; Karin Schindler; Amand Floriaan Schmidt; Börge Schmidt; Carsten O. Schmidt; Andrea Schneider; Peter Schnohr; Catherine Mary Schooling; Ben Schöttker; Sara Schramm; Stine Schramm; Helmut Schröder; Constance Schultsz; Gry Schultz; Matthias B. Schulze; Aletta E. Schutte; Moslem Sedaghattalab; Rusidah Selamat; Abhijit Sen; Idowu O. Senbanjo; Sadaf G. Sepanlou; Guillermo Sequera; Luis Serra-Majem; Jennifer Servais; Ľudmila Ševčíková; Ronel Sewpaul; Svetlana A. Shalnova; Teresa Shamah-Levy; Seyed Morteza Shamshirgaran; Shubash Shander; Coimbatore Subramaniam Shanthirani; Maryam Sharafkhah; Sanjib K. Sharma; Almaz Sharman; Jonathan E. Shaw; Amaneh Shayanrad; Ali Akbar Shayesteh; Nurzhamal Sheisheeva; Ching-Fen Shen; Lela Shengelia; Kenji Shibuya; Hana Shimizu-Furusawa; Tal Shimony; Avi Shina; Igor D. Shkrobanets; Marat Shoranov; Khairil Si-Ramlee; Alfonso Siani; Abla M. Sibai; Labros S. Sidossis; Mark J. Siedner; Natalia Silitrari; Antonio M. Silva; Caroline Ramos de Moura Silva; Diego Augusto Santos Silva; Kelly Samara Silva; Xueling Sim; Mary Simon; Judith Simons; Leon A. Simons; Ivan Simunovic; Agneta Sjöberg; Michael Sjöström; Elena V. Skoblina; Natalia A. Skoblina; Tatyana Slazhnyova; Jolanta Slowikowska-Hilczer; Przemysław Slusarczyk; Liam Smeeth; Lee Smith; Hung-Kwan So; Fernanda Cunha Soares; Grzegorz Sobek; Eugène Sobngwi; Morten Sodemann; Stefan Söderberg; Moesijanti Y. E. Soekatri; Agustinus Soemantri; Raquel Soler-Blasco; Vincenzo Solfrizzi; Yuliya V. Solovieva; Mohammad Hossein Somi; Emily Sonestedt; Sajid Soofi; Thorkild I. A. Sørensen; Elin P. Sørgjerd; Victoria E. Soto-Rojas; Aïcha Soumaré; Alfonso Sousa-Poza; Mafalda Sousa-Uva; Mam Sovatha; Agnieszka Sozańska; Bente Sparboe-Nilsen; Karen Sparrenberger; Vita Speckauskiene; Phoebe R. Spencer; Angela Spinelli; Igor Spiroski; Jan A. Staessen; Aleksandra Stamenova; Hanspeter Stamm; Laura Stanciulescu; Andreas Stang; Kaspar Staub; Bill Stavreski; Jostein Steene-Johannessen; Peter Stehle; Aryeh D. Stein; Silje Steinsbekk; George S. Stergiou; Jochanan Stessman; Jutta Stieber; Doris Stöckl; Jakub Stokwiszewski; Katarzyna Stoś; Ekaterina Stoyanova; Gareth Stratton; Karien Stronks; Maria Wany Strufaldi; Lela Sturua; Milton F. Suarez-Ortegón; Phalakorn Suebsamran; Mindy S. Sugiyama; Machi Suka; Gerhard Sulo; Malin Sund; Johan Sundström; Yn-Tz Sung; Jordi Sunyer; Unursaikhan Surenjav; Paibul Suriyawongpaisal; Kitti Susovits; Nabil William G. Sweis; Boyd A. Swinburn; René Charles Sylva; Unni Syversen; Lucjan Szponar; Yasuharu Tabara; Lorraine Tabone; E. Shyong Tai; Konstantinos D. Tambalis; Mari-Liis Tammesoo; Abdonas Tamosiunas; Eng Joo Tan; Baimakhan Tanabayev; Nikhil Tandon; Xun Tang; Maya Tanrygulyyeva; Frank Tanser; Yong Tao; Mohammed Rasoul Tarawneh; Jakob Tarp; Carolina B. Tarqui-Mamani; Radka Taxová Braunerová; Anne Taylor; Félicité Tchibindat; Saskia Te Velde; William R. Tebar; Fahimeh R. Tehrani; Grethe S. Tell; Tania Tello; Masresha Tessema; Lukas Teufl; Yih Chung Tham; K. R. Thankappan; Holger Theobald; Xenophon Theodoridis; Sathish Thirunavukkarasu; Nihal Thomas; Barbara Thorand; Amanda G. Thrift; Ľubica Tichá; Erik J. Timmermans; Dwi Hapsari Tjandrarini; Anne Tjonneland; Ervin Toçi; Maryam Tohidi; Hanna K. Tolonen; Janne S. Tolstrup; Maciej Tomaszewski; Murat Topbas; Roman Topór-Mądry; Pere Torán-Monserrat; Liv Elin Torheim; Michael J. Tornaritis; Maties Torrent; Laura Torres-Collado; Duarte Torres; Silvia Torres; Stefania Toselli; Giota Touloumi; Luciana Tovo-Rodrigues; Pierre Traissac; Thi Tuyet-Hanh Tran; Mark S. Tremblay; Areti Triantafyllou; Antonia Trichopoulou; Oanh T. H. Trinh; Justina Trišauskė; Atul Trivedi; Alexander C. Tsai; Lechaba Tshepo; Thomas Tsiampalis; Maria Tsigga; Panagiotis Tsintavis; Shoichiro Tsugane; John Tuitele; Azaliia M. Tuliakova; Marshall K. Tulloch-Reid; Fikru Tullu; Tomi-Pekka Tuomainen; Jaakko Tuomilehto; Maria L. Turley; Gilad Twig; Per Tynelius; Evangelia Tzala; Themistoklis Tzotzas; Christophe Tzourio; Nwannedimma Udoji; Peter Ueda; Eunice Ugel; Flora A. M. Ukoli; Hanno Ulmer; Belgin Unal; Zhamyila Usupova; Hannu M. T. Uusitalo; Nalan Uysal; Sergio Valdes; Gonzalo Valdivia; Susana Vale; Popov I. Valery; Majid Valizadeh; Damaskini Valvi; Rob M. van Dam; Bert-Jan van den Born; Johan Van der Heyden; Yvonne T. van der Schouw; Koen Van Herck; Wendy Van Lippevelde; Hoang Van Minh; Natasja M. Van Schoor; Irene G. M. van Valkengoed; Dirk Vanderschueren; Diego Vanuzzo; Anette Varbo; Gregorio Varela-Moreiras; Luz Nayibe Vargas; Senthil K. Vasan; Daniel G. Vasques; Radu Vatasescu; Tomas Vega; Toomas Veidebaum; Gustavo Velasquez-Melendez; Biruta Velika; Michel Velten; Charlotte Verdot; Maïté Verloigne; Giovanni Veronesi; W. M. Monique Verschuren; Germán Vicente-Rodríguez; Cesar G. Victora; Josep Vidal-Conti; Giovanni Viegi; Lucie Viet; Frøydis N. Vik; Monica Vilar; Salvador Villalpando; Luis Villarroel; Jesus Vioque; Napaphan Viriyautsahakul; Jyrki K. Virtanen; Marjolein Visser; Bharathi Viswanathan; Chiranthika Vithana; Mihaela Vladulescu; Tiina Vlasoff; Peter Vollenweider; Henry Völzke; Georgia Vourli; Ari Voutilainen; Martine Vrijheid; Tanja G. M. Vrijkotte; Silvije Vuletić; Alisha N. Wade; Wakenge Wakilongo; Thomas Waldhör; Janette Walton; Elvis O. A. Wambiya; Wan Mohamad Wan Bebakar; Wan Nazaimoon Wan Mohamud; Rildo de Souza Wanderley Júnior; Chongjian Wang; Huijun Wang; Ningli Wang; Qian Wang; Xiangjun Wang; Ya Xing Wang; Yi-Ren Wang; S. Goya Wannamethee; Nicholas Wareham; Olivia Wartha; Adelheid Weber; Karen Webster-Kerr; Niels Wedderkopp; Daniel Weghuber; Li Wei; Wenbin Wei; Aneta Weres; Bo Werner; Leo D. Westbury; Peter H. Whincup; Lars Wichstrøm; Kremlin Wickramasinghe; Kurt Widhalm; Indah S. Widyahening; Andrzej Więcek; Nilmini Wijemunige; Philipp S. Wild; Rainford J. Wilks; Johann Willeit; Karin Willeit; Peter Willeit; Julianne Williams; Tom Wilsgaard; James P. Wirth; Agnieszka Wiśniowska-Szurlej; Bogdan Wojtyniak; Meseret Woldeyohannes; Kathrin Wolf; Roy A. Wong-McClure; Andrew Wong; Emily B. Wong; Jyh Eiin Wong; Mark Woodward; Agnieszka E. Woźniak; Frederick C. Wu; Hon-Yen Wu; Jianfeng Wu; Li Juan Wu; Shouling Wu; Justyna Wyszyńska; Haiquan Xu; Liang Xu; Can Can Xue; Nor Azwany Yaacob; Uruwan Yamborisut; Li Yan; Lily D. Yan; Weili Yan; Ling Yang; Xiaoguang Yang; Yang Yang; Nazan Yardim; Chao-Yu Yeh; Martha Yépez García; Panayiotis K. Yiallouros; Agneta Yngve; Chandra Mandil Yogal; Moein Yoosefi; Akihiro Yoshihara; Yoto Yotov; Qi Sheng You; Yu-Ling Yu; Yunjiang Yu; Safiah Md Yusof; Ahmad Faudzi Yusoff; Luciana Zaccagni; Vassilis Zafiropulos; Ahmad A. Zainuddin; Farhad Zamani; Sabina Zambon; Antonis Zampelas; Hana Zamrazilová; Maria Elisa Zapata; Tomasz Zatoński; Ko Ko Zaw; Ayman A. Zayed; Tomasz Zdrojewski; Magdalena Żegleń; Kristyna Zejglicova; Girum Zeleke; Tajana Zeljkovic Vrkic; Yi Zeng; Andrea Zentai; Bing Zhang; Luxia Zhang; Zhen-Yu Zhang; Dong Zhao; Ming-Hui Zhao; Wenhua Zhao; Yanitsa V. Zhecheva; Wei Zheng; Bekbolat Zholdin; Maigeng Zhou; Dan Zhu; Oleg F. Zhukov; Sophia Zollner-Kiechl; Paul Zimmet; Marie Zins; Emanuel Zitt; Yanina Zocalo; Julio Zuñiga Cisneros; Monika Zuziak; Majid Ezzati; Brito, Miguel
Global reporting of obesity is commonly based on comparisons over multiple decades1 and lacks a granular and systematic analysis of its dynamics. We used 4,050 population-based studies with measured height and weight data on 232 million participants to assess the worldwide dynamics of obesity from 1980 to 2024. The rise in obesity decelerated in school-aged children and adolescents throughout the 1990s in many high-income countries, and subsequently plateaued in most at age-standardized prevalences spanning 20 percentage points, from 3-4% for girls in Japan, Denmark, and France to 23% for boys in the USA. There were indications of a small decline in obesity in children and adolescents in some high-income western countries (for example, Italy, Portugal, and France) since the 2000s. Similar trends were seen in some countries in Central and Eastern Europe. In adults, the rise in obesity slowed down in high-income western countries about a decade after children, followed by a plateau or possibly a small reversal of the rise in some countries (for example, Spain). In most low- and middle-income countries, the annual absolute change in prevalence has remained stable or increased over time, even though prevalence has surpassed that of high-income countries. These highly varied dynamics suggest that the social, economic, and technological trends that influence the availability, affordability, and use of different foods may have helped control the rise in obesity in high-income countries, but require policy interventions in low-income and middle-income countries.
Sand quality on Portuguese blue flagged beaches: fungal and faecal contamination across two bathing seasons
Publication . Silva, Ana Margarida; Sarioglou, Konstantina; Silva, Susana; Viegas, Carla; Ribeiro, Edna; Rebelo, Maria Teresa; Brandão, João
There is growing concern about the quality of beach sand, as users tend to spend most of their time on the sand rather than in the water. Numerous pathogenic agents have reportedly been isolated from sand, including bacteria, nematodes, and opportunistic fungi. The ability of sand to retain pollutants and facilitate the transmission of pathogens raises public health concerns. We analysed sand-monitoring data from the 2024 and 2025 bathing seasons on Blue Flag beaches to find trends and patterns in total fungal counts, enterococci, and E. coli. The values recorded for microorganisms showed considerable variability, which may reflect the combined influence of multiple climatic, environmental, and anthropogenic factors on their presence in beach sand. Our findings suggest that the total fungal count on coastal beaches may be influenced by periods of rainfall, which increases the fungal load in the sand. Values recorded from inland beaches vary considerably between beaches, which may reflect the influence of local environmental characteristics, particularly vegetation and beach morphology, although the smaller number of inland samples also makes it difficult to define clear patterns and consistent reference values for this parameter. Bacterial indicators may be particularly influenced by occasional anthropogenic disturbances and contamination events. This study adds significantly to the understanding of the microbiological quality of beach sand, encouraging the integration of sand monitoring into environmental surveillance and management programmes.
Exploring how research skills are taught and assessed in medical imaging and radiation therapy higher education: an international snapshot
Publication . Di Michele, L.; Johnson, N.; McDermott, B.; Podkrajšek, M.; Ranshi, R.; Silva, I.; Vieira, Lina Oliveira; Ghotra, S.S.
Introduction: Research competence is a core attribute of contemporary medical imaging and radiation therapy (MIRT); however, how research skills are taught and assessed across international radiography programs remains poorly understood. This study aims to explore research skills that are taught and assessed in different medical imaging and radiation therapy (MIRT) higher education institutions internationally, focusing on the curricula, experience of students, and academics. Methods: A two-phase design study was employed. Phase one involved an analysis of undergraduate MIRT curricula from nine international higher education institutions, examining programme structure, research credit allocation, research-related subjects, and teaching strategies. Phase two consisted of semi-structured focus groups with students and academic staff. All sessions were audio-recorded and transcribed using Zoom, with the transcripts checked for accuracy, and analysed using reflexive thematic analysis supported by NVivo software. Results: Data were collected from nine institutions across three continents. Curriculum analysis revealed international variability in the scope, timing, and depth of research integration, with research-related content embedded at differing stages of training. Reflexive thematic analysis identified three overarching themes: 1. research skills in the curriculum, 2. Navigating the research learning experience, and 3. Professional identity and practice. Conclusion: This study demonstrates substantial international variability in research education for medical imaging and radiation therapy students, leading to differences in research capability among graduates. Importantly, research education also shapes how practitioners value and engage with research, influencing professional culture within the field. Impacts on practice: Systematically scaffolding research skills across undergraduate radiography programs can support progressive learning and promote sustained engagement with research throughout the curriculum. Embedding clinically relevant research throughout education can sustain engagement with research, strengthening evidence-based practice and supporting a professional culture that values research in MIRT practice.
Outer retinal band segmentation in healthy subjects: comparative study between human grading and deep convolutional neural networks
Publication . Afonso, João Duarte; Camacho, Pedro; Pereira, Bruno; Marques, João Pedro; Lopes, Daniel Simões; Cabral, Diogo
Background: Accurate identification of outer retinal bands (ORBs) on spectral-domain optical coherence tomography (SD-OCT) is clinically important for the assessment and monitoring of several retinal diseases. However, manual segmentation of these ORBs is time-consuming and subject to considerable intra- and inter-observer variability. Deep convolutional neural networks (dCNNs) offer a promising approach for achieving more consistent and reproducible segmentation of retinal microstructures, yet their performance for individual ORBs and their dependence on grader reliability remain insufficiently characterized. This study aimed to compare manual grading and different dCNN architectures for the segmentation of individual ORBs in healthy subjects, while assessing the reproducibility of human annotations and the performance of automated methods. Methods: A cross-sectional observational study was conducted using foveal-centered SD-OCT scans obtained from healthy participants. Manual segmentation of the second hyperreflective band (Band 2), the third and fourth hyperreflective bands (Band 3+4), and photoreceptor outer segments (POS) was performed by two trained graders using onboard OCT software. Reproducibility was assessed using the intraclass and interclass correlation coefficient (ICC). Human annotations were used to train different dCNNs pretrained with Sparse masked modelling on unlabelled data. The performance of the dCNNs was evaluated using the dice score and pixel difference analyses. Results: One hundred eyes of healthy subjects were included. The intraclass correlation values were 0.737 (0.689, 0.779), 0.830 (0.795, 0.860), and 0.878 (0.852, 0.900), and the ICCs were 0.104 (-0.049, 0.253), 0.810 (0.740, 0.862), and 0.752 (0.678, 0.812) for Band 2, Band 3+4, and POS, respectively. From the dCNN, DRUNET showed the best performance: 0.916 for Band 2, 0.924 for Band 3+4, and 0.910 for POS. Pixel difference analysis between DRUNET and grader 1 showed a deviation of 0.89±0.44. Conclusions: Manual segmentation of ORBs demonstrated moderate to high repeatability, whereas Band 2 segmentation showed low reproducibility. DRUNET outperformed other dCNN architectures, showing great potential to reduce inter-observer variability.