Publicação
The recycling of tubulin heterodimer by tubulin cofactors TBCA, TBCB, and TBCE is blocked by colchicine
| dc.contributor.author | Nolasco, Sofia | |
| dc.contributor.author | Bellido, J. | |
| dc.contributor.author | Serna, M. | |
| dc.contributor.author | Carmona, Bruno | |
| dc.contributor.author | Soares, Helena | |
| dc.contributor.author | Zabala, J. | |
| dc.date.accessioned | 2022-12-30T18:08:08Z | |
| dc.date.available | 2022-12-30T18:08:08Z | |
| dc.date.issued | 2021-11 | |
| dc.description.abstract | Colchicine has been used to treat gout and effectively prevent autoinflammatory diseases and primary and recurrent pericarditis episodes. The anti-inflammatory action of colchicine seems to result from compromised microtubule (MT) networks that affect several inflammatory pathways in cells that mediate immune response like the entire NLRP3 inflammasome. | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.citation | Nolasco S, Bellido J, Serna M, Carmona B, Soares H, Zabala J. The recycling of tubulin heterodimer by tubulin cofactors TBCA, TBCB, and TBCE is blocked by colchicine. In: 2021 ASCB Annual Meeting abstracts. Mol Biol Cell. 2021;32(22):poster 843. | pt_PT |
| dc.identifier.doi | 10.1091/mbc.E21-11-0545 | pt_PT |
| dc.identifier.uri | http://hdl.handle.net/10400.21/15215 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.publisher | American Society for Cell Biology | pt_PT |
| dc.relation.publisherversion | https://www.molbiolcell.org/doi/10.1091/mbc.E21-11-0545 | pt_PT |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | pt_PT |
| dc.subject | Tubulin | pt_PT |
| dc.subject | Colchicine | pt_PT |
| dc.subject | Inflammatory disease | pt_PT |
| dc.title | The recycling of tubulin heterodimer by tubulin cofactors TBCA, TBCB, and TBCE is blocked by colchicine | pt_PT |
| dc.type | conference object | |
| dspace.entity.type | Publication | |
| oaire.citation.issue | 12 | pt_PT |
| oaire.citation.title | Molecular Biology of the Cell | pt_PT |
| oaire.citation.volume | 32 | pt_PT |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | conferenceObject | pt_PT |
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