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Reference values for spirometry in elderly individuals: a cross-sectional study of different reference equations

2018-01Journal article Open access
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dc.contributor.authorBelo, Joana
dc.contributor.authorPalmeiro, Teresa
dc.contributor.authorCaires, Iolanda
dc.contributor.authorPapoila, Ana L.
dc.contributor.authorAlves, Marta
dc.contributor.authorCarreiro-Martins, Pedro
dc.contributor.authorBotelho, Maria A.
dc.contributor.authorNeuparth, Nuno
dc.date.accessioned2018-06-11T15:24:03Z
dc.date.available2018-06-11T15:24:03Z
dc.date.issued2018-01
dc.description.abstractBackground: Spirometry is the single most important test for the evaluation of the respiratory function. The results are interpreted by comparing measured data with predicted values previously obtained from a reference population. Reference equations for spirometry have been discussed previously. The aim of this study was to compare reference values based on National Health and Nutrition Assessment Survey (NHANES III), European Community of Steel and Coal (ECSC), and Global Lung Initiative (GLI) equations in an elderly sample population. Methods: Subjects from the Geriatric Study on Health Effects of Air Quality in elder care centers who met the inclusion criteria were enrolled. Spirometry was performed according to international guidelines. The forced vital capacity, forced expiratory volume in 1 s, and the FEV1/FVC ratio was reported as percentages of the predicted value, and the lower limit of normality was calculated. Results: Out of 260 elderly patients, 69.6% were women; the mean age was 83.0 ± 6.46 years with an age range of 65-95 years. The lowest %FVC and %FEV1 values were obtained using the GLI reference equations. However, when NHANES III equations were used, the FEV1/FVC ratio was higher than ratios obtained from GLI and ECSC equations. The prevalence of airway obstruction was highest using ECSC equations, while GLI equations demonstrated more restrictive defects. Conclusions: The present study showed meaningful differences in the reference values, and consequently, in the results obtained using NHANES III, ECSC, and GLI reference equations. The spirometry interpretation was also influenced by the reference equations used.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationBelo J, Palmeiro T, Caires I, Papoila AL, Alves M, Carreiro-Martins P, et al. Reference values for spirometry in elderly individuals: a cross-sectional study of different reference equations. Multidiscip Respir Med. 2018;13:4.pt_PT
dc.identifier.doi10.1186/s40248-017-0112-5pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.21/8616
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherBMCpt_PT
dc.relation.publisherversionhttps://mrmjournal.biomedcentral.com/articles/10.1186/s40248-017-0112-5pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectEuropean Community of Steel and Coalpt_PT
dc.subjectECSCpt_PT
dc.subjectGlobal Lung Initiativept_PT
dc.subjectElderlypt_PT
dc.subjectNational Health and Nutrition Assessment Surveypt_PT
dc.subjectNHANES IIIpt_PT
dc.subjectSpirometrypt_PT
dc.subjectReference valuespt_PT
dc.titleReference values for spirometry in elderly individuals: a cross-sectional study of different reference equationspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.startPage4pt_PT
oaire.citation.titleMultidisciplinary Respiratory Medicinept_PT
oaire.citation.volume13pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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