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Interaction of formaldehyde and tobacco smoking in the frequency of micronucleus and the XRCC3 Thr241Met polymorphism

2010-09Conference object Open access
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dc.contributor.authorLadeira, Carina
dc.contributor.authorGomes, Manuel C.
dc.contributor.authorBrito, Miguel
dc.date.accessioned2011-11-28T14:05:28Z
dc.date.available2011-11-28T14:05:28Z
dc.date.issued2010-09
dc.description.abstractFormaldehyde is classified by IARC as carcinogenic to humans (nasopharyngeal cancer). Tobacco smoke has been epidemiologically associated to a higher risk of development of cancer, especially in the oral cavity, larynx and lungs, as these are places of direct contact with many carcinogenic tobacco’s compounds. XRCC3 is involved in homologous recombination repair of cross-links and chromosomal double-strand breaks (Thr241Met polymorphism). The aim of the study is to determine whether there is an in vivo association between genetic polymorphism of the gene XRCC3 and the frequency of genotoxicity biomarkers in subjects exposed or not to formaldehyde and with or without tobacco consumption.por
dc.identifier.citationLadeira C, Gomes MC, Brito M. Interaction of formaldehyde and tobacco smoking in the frequency of micronucleus and the XRCC3 Thr241Met polymorphism. In 8th International Symposium on Biological Monitoring in Occupational and Environmental Health, Finland, 6th September 2010. Oral presentation.por
dc.identifier.urihttp://hdl.handle.net/10400.21/678
dc.language.isoengpor
dc.peerreviewedyespor
dc.subjectAnatomia patológicapor
dc.subjectSaúde ocupacionalpor
dc.subjectFormaldeídopor
dc.subjectTabagismopor
dc.subjectConsumo de álcoolpor
dc.subjectFactor de riscopor
dc.titleInteraction of formaldehyde and tobacco smoking in the frequency of micronucleus and the XRCC3 Thr241Met polymorphismpor
dc.typeconference object
dspace.entity.typePublication
person.familyNameLadeira
person.familyNameBrito
person.givenNameCarina
person.givenNameMiguel
person.identifier144237
person.identifier.ciencia-id801C-1BBA-1D9E
person.identifier.ciencia-id231F-F341-7E93
person.identifier.orcid0000-0001-5588-0074
person.identifier.orcid0000-0001-6394-658X
person.identifier.ridJ-2572-2012
person.identifier.ridA-7970-2016
person.identifier.scopus-author-id36463788000
person.identifier.scopus-author-id35224551000
rcaap.rightsopenAccesspor
rcaap.typeconferenceObjectpor
relation.isAuthorOfPublication1aef4b60-4197-436b-84ab-80d31cbaed33
relation.isAuthorOfPublication4252d8e0-800c-4d67-8b13-0b711d860669
relation.isAuthorOfPublication.latestForDiscovery1aef4b60-4197-436b-84ab-80d31cbaed33

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