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Chitosan nanoparticles loaded with minocycline targeting osteomyelitis

dc.contributor.authorZegre, Miguel
dc.contributor.authorBastron, S.
dc.contributor.authorRibeiro, I. A.
dc.contributor.authorCaetano, Liliana Aranha
dc.contributor.authorGonçalves, L.
dc.contributor.authorBettencourt, A.
dc.date.accessioned2022-12-09T12:33:20Z
dc.date.available2022-12-09T12:33:20Z
dc.date.issued2022-11
dc.description.abstractEffective control of osteomyelitis (bone infection) with reduced toxicity is a current challenge. Targeted and controlled drug delivery systems allow: decreased toxicity, upgraded drug targeting, and improved therapeutic effect. Strategy: a) Innovative chitosan nanoparticulate system: nanoparticles loaded with minocycline (antibacterial), and alternative as a local delivery system; b) Nanoparticles and biofilms: advantages: enhanced bioavailability, targeted delivery of antibiotics magnification, local release of antibiotics, controlled and sustained release, and protection against deactivating enzymes.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationZegre M, Bastron S, Ribeiro IA, Caetano LA, Gonçalves L, Bettencourt A. Chitosan nanoparticles loaded with minocycline targeting osteomyelitis. In: Simposio Iberoamericano COIFFA-2022 [online], Mexico, November 18-19, 2022.pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.21/15136
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectOsteomyelitispt_PT
dc.subjectChitosanpt_PT
dc.subjectNanoparticlespt_PT
dc.titleChitosan nanoparticles loaded with minocycline targeting osteomyelitispt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferencePlaceMexicopt_PT
person.familyNameAranha Caetano
person.givenNameLiliana
person.identifier.ciencia-id9716-9DAC-532A
person.identifier.orcid0000-0003-1496-2609
rcaap.rightsopenAccesspt_PT
rcaap.typeconferenceObjectpt_PT
relation.isAuthorOfPublication6517c656-f913-4f54-8682-77c2856c9e4c
relation.isAuthorOfPublication.latestForDiscovery6517c656-f913-4f54-8682-77c2856c9e4c

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