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Sensitisation to aeroallergens in relation to asthma and other allergic diseases in Angolan children: a cross-sectional study

2020-02Journal article Restricted access
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dc.contributor.authorArrais, Margarete
dc.contributor.authorLulua, Ofélia
dc.contributor.authorQuifica, Francisca
dc.contributor.authorRosado-Pinto, José
dc.contributor.authorGama, Jorge
dc.contributor.authorBrito, Miguel
dc.contributor.authorTaborda-Barata, Luis
dc.date.accessioned2020-02-19T13:26:26Z
dc.date.available2020-02-19T13:26:26Z
dc.date.issued2020-02
dc.description.abstractIntroduction and Objectives: In Africa, few studies of sensitization profiles have been performed in children or adolescents and, in Angola, there are none. The objectives of the present study were to assess the sensitization profile of Angolan schoolchildren and to determine the relationship between that pattern, sociodemographic factors, asthma, and other allergic diseases. Materials and Methods: Cross-sectional, observational study in 5-14-year-old children, performed between September and November 2017, in the Province of Bengo, Angola. Five schools (15%) were randomly selected in the geographical area of the study: three from an urban area, and two from a rural area. Data were collected using the Portuguese versions of the ISAAC questionnaires for children and adolescents, regarding asthma, rhinitis, and eczema. Skin prick tests (SPT) were performed with a battery of 12 aeroallergens. Stools were assessed for the presence of helminths. Descriptive statistics were used, as well as a univariate calculation of odds ratios. Results: Sensitisation to aeroallergens was low (8%) and most sensitized children were asymptomatic. Most frequent sensitizations involved house dust mites, cockroaches, or fungi, and a high proportion of children (78.1%) were monosensitized. No relationship was detected between sensitizations and asthma, rhinitis or eczema. Place of residence, gender, age or helminthic infection did not affect the probability of having positive SPTs. Conclusions: The most frequent sensitizations in children from Bengo Province in Angola involve house dust mites, followed by cockroaches and fungi. No relationship was found between atopic sensitization and asthma or other allergic diseases.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationArrais M, Lulua O, Quifica F, Rosado-Pinto J, Gama JM, Brito M, et al. Sensitisation to aeroallergens in relation to asthma and other allergic diseases in Angolan children: a cross-sectional study. Allergologia et Immunopathologia. 2020;48(3):281-9.pt_PT
dc.identifier.doi10.1016/j.aller.2019.10.005pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.21/11121
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relation.publisherversionhttps://www.sciencedirect.com/science/article/pii/S0301054620300057?via%3Dihubpt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectAllergenspt_PT
dc.subjectAsthmapt_PT
dc.subjectAtopypt_PT
dc.subjectSensitisationpt_PT
dc.subjectSkin prick testspt_PT
dc.subjectChildrenpt_PT
dc.subjectAngolapt_PT
dc.titleSensitisation to aeroallergens in relation to asthma and other allergic diseases in Angolan children: a cross-sectional studypt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage289pt_PT
oaire.citation.issue3pt_PT
oaire.citation.startPage281pt_PT
oaire.citation.titleAllergologia et Immunopathologiapt_PT
oaire.citation.volume48pt_PT
person.familyNameBrito
person.givenNameMiguel
person.identifier.ciencia-id231F-F341-7E93
person.identifier.orcid0000-0001-6394-658X
person.identifier.ridA-7970-2016
person.identifier.scopus-author-id35224551000
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication4252d8e0-800c-4d67-8b13-0b711d860669
relation.isAuthorOfPublication.latestForDiscovery4252d8e0-800c-4d67-8b13-0b711d860669

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