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Analysis of the interference of endogenous circadian rhythms on 3'- deoxy- 3'- [18F]Fluorothymidine physiological uptake at the human bone marrow

dc.contributor.authorVarela, N. M.
dc.contributor.authorLucena, Filipa
dc.contributor.authorRaminhas Carapinha, Maria João
dc.contributor.authorVieira, Lina Oliveira
dc.date.accessioned2013-05-17T15:11:32Z
dc.date.available2013-05-17T15:11:32Z
dc.date.issued2011-10
dc.description.abstractThe main purpose of the present study is to determine if the circadian rhythms present in the human bone marrow are likely to influence 3’- deoxy- 3’-[18F] Fluorothymidine (18F-FLT) uptake in the same organ. The 18F-FLT is a Thymidine analogous proliferation agent. The relatively high physiological uptake of this tracer in the bone marrow diminishes the Tumor/Background (T/B) ratio, decreasing the detection accuracy of PET/CT and possibly affecting SUV quantifications.por
dc.identifier.citationVarela NM, Lucena F, Carapinha MJ, Vieira L. Analysis of the interference of endogenous circadian rhythms on 3'- deoxy- 3'- [18F]Fluorothymidine physiological uptake at the human bone marrow. Eur j Nucl Med Mol Imaging. 2011;38(2 Suppl):S452.por
dc.identifier.issn1619-7089
dc.identifier.urihttp://hdl.handle.net/10400.21/2514
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherSpringerpor
dc.relation.publisherversionhttp://link.springer.com/content/pdf/10.1007%2Fs00259-011-1913-y.pdfpor
dc.subjectNuclear medicinepor
dc.subjectEndogenous circadian rhythmspor
dc.subjectHuman bone marrowpor
dc.subject18F-Fluorothymidinepor
dc.titleAnalysis of the interference of endogenous circadian rhythms on 3'- deoxy- 3'- [18F]Fluorothymidine physiological uptake at the human bone marrowpor
dc.typeconference object
dspace.entity.typePublication
oaire.citation.endPageS452por
oaire.citation.startPageS452por
oaire.citation.titleEuropean Journal of Nuclear Medicine and Molecular Imagingpor
oaire.citation.volume38por
person.familyNameRaminhas Carapinha
person.familyNameVieira
person.givenNameMaria João
person.givenNameLina Oliveira
person.identifier.ciencia-idF416-6BAA-D4D7
person.identifier.ciencia-idD316-5085-2DE0
person.identifier.orcid0000-0002-3343-6500
person.identifier.orcid0000-0002-7109-6535
person.identifier.ridZ-1221-2018
person.identifier.ridP-7426-2015
person.identifier.scopus-author-id55258594400
rcaap.rightsopenAccesspor
rcaap.typeconferenceObjectpor
relation.isAuthorOfPublication406de1e9-dae8-488d-bcdc-fef1da6526a1
relation.isAuthorOfPublication0b528961-126c-42d6-a4e7-2a10423c94b8
relation.isAuthorOfPublication.latestForDiscovery406de1e9-dae8-488d-bcdc-fef1da6526a1

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