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Vagus nerve stimulation for the management of immune-mediated inflammatory diseases

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datacite.subject.sdg03:Saúde de Qualidade
dc.contributor.authorTarn, Jessica
dc.contributor.authorPinto, Ines Figueiredo
dc.contributor.authorNg, Wan-Fai
dc.contributor.editorStaats, P. S.
dc.contributor.editorAyata, C.
dc.contributor.editorAbd-Elsayed, A.
dc.date.accessioned2025-03-03T14:57:12Z
dc.date.available2025-03-03T14:57:12Z
dc.date.issued2025
dc.description.abstractThe vagus nerve is a key component of several homeostatic axes including the cholinergic antiinflammatory pathway, hypothalamic–pituitary-adrenergic axis, and the brain-gut axis, all of which play important roles in the regulation of the immune system. Autonomic dysfunction has been described in many immune-mediated inflammatory diseases (IMIDs). In addition, several pilot studies have shown that vagus nerve stimulation leads to improvement in several IMIDs. Taken together, the vagus nerve is a promising novel therapeutic target for the management of IMIDs.eng
dc.identifier.citationTarn J, Pinto IF, Ng WF. Vagus nerve stimulation for the management of immune-mediated inflammatory diseases. In: Staats PS, Ayata C, Abd-Elsayed A, editors. Vagus nerve stimulation. Academic Press; 2025. p. 275-86.
dc.identifier.doi10.1016/b978-0-12-816996-4.00026-5
dc.identifier.isbn9780128169964
dc.identifier.urihttp://hdl.handle.net/10400.21/21626
dc.language.isoeng
dc.peerreviewedyes
dc.publisherElsevier
dc.relation.hasversionhttps://www.sciencedirect.com/science/article/abs/pii/B9780128169964000265
dc.relation.ispartofVagus Nerve Stimulation
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectImmunemediated inflammatory diseases
dc.subjectVagus nerve
dc.subjectAutonomic nervous system
dc.subjectCholinergic antiinflammatory
dc.subjectHypothalamic–pituitary-adrenal
dc.subjectBrain-gut
dc.subjectInflammatory bowel disease
dc.subjectPrimary Sjogren’s syndrome
dc.subjectScleroderma
dc.subjectSystemic lupus erythematosus
dc.titleVagus nerve stimulation for the management of immune-mediated inflammatory diseaseseng
dc.typebook part
dspace.entity.typePublication
oaire.citation.endPage286
oaire.citation.startPage275
oaire.citation.titleVagus nerve stimulation
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85

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