Repository logo
 
Publication

Evaluation of SPECT imaging: a multi-center and multi-vendor phantom study

2022-12Preprint Open access
Simple item page
dc.contributor.authorGonçalves, Maria Inês Rebelo
dc.contributor.authorParafita, Rui
dc.contributor.authorCosta, Mauro
dc.contributor.authorGeão, Ana
dc.contributor.authorPereira, Edgar
dc.contributor.authorVieira, Lina Oliveira
dc.date.accessioned2023-01-30T11:38:46Z
dc.date.available2023-01-30T11:38:46Z
dc.date.issued2022-12
dc.description.abstractBackground: Single-photon emission computed tomography (SPECT) is a nuclear medicine (NM) imaging method sensitive to the evaluation and quantification of physiological processes in patients. However, there are different factors that affect qualitatively and quantitatively the SPECT images and, consequently, the reliability of the data. There is a degree of variability underlying the intrinsic performance of systems from the same or different manufacturers. In addition, the different configurations of the gamma cameras (GC) and the acquisition and reconstruction protocols used may lead to heterogeneity of results. This study compared SPECT images acquired in three GC from three NM centers, using the Jaszczak and NEMA IEC Body phantoms, filled with a homogeneous solution of technetium-99m. Acquisitions were performed in each GC, following the protocols used in the clinical practice of the respective NM center, and the images were analyzed and compared in terms of spatial resolution, sensitivity, noise, contrast, and contrast recovery (CR). Subsequently, the processing and reconstruction parameters were harmonized to assess their impact on the standardization of results. Results: With the clinical protocols, the images acquired with the three GC showed small differences in spatial resolution, noise, and contrast, with the greatest difference being observed in the quantitative accuracy, since the CR has achieved variabilities of 0.17 and 0.28, for different activity concentrations. This intersystem variability was reduced to 0.09 and 0.08 after reconstruction algorithm standardization. However, this change increased the differences in the contrast percentage. Conclusion: GC from different manufacturers showed the greatest heterogeneity of results, however, by eliminating possible sources of variation it is possible to reduce the differences between systems. It was demonstrated the need to include different parameters for the evaluation and comparison of SPECT images so that procedures can be established between the different NM centers to ensure a trade-off between the various parameters assessed here, as the improvement of some usually leads to the deterioration of others.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationGonçalves MI, Parafita R, Costa M, Geão A, Pereira E, Vieira L. Evaluation of SPECT imaging: a multi-center and multi-vendor phantom study [preprint]. EJNMMI Physics. 2022 December 22.pt_PT
dc.identifier.doi10.21203/rs.3.rs-2347441/v1pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.21/15421
dc.language.isoengpt_PT
dc.peerreviewednopt_PT
dc.publisherResearch Squarept_PT
dc.relation.publisherversionhttps://www.researchsquare.com/article/rs-2347441/v1pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectNuclear medicinept_PT
dc.subjectSPECTpt_PT
dc.subjectSpatial resolutionpt_PT
dc.subjectSensitivitypt_PT
dc.subjectNoisept_PT
dc.subjectContrastpt_PT
dc.subjectImage reconstructionpt_PT
dc.subjectStandardizationpt_PT
dc.titleEvaluation of SPECT imaging: a multi-center and multi-vendor phantom studypt_PT
dc.typepreprint
dspace.entity.typePublication
person.familyNameVieira
person.givenNameLina Oliveira
person.identifier.ciencia-idD316-5085-2DE0
person.identifier.orcid0000-0002-7109-6535
person.identifier.ridP-7426-2015
person.identifier.scopus-author-id55258594400
rcaap.rightsopenAccesspt_PT
rcaap.typepreprintpt_PT
relation.isAuthorOfPublication0b528961-126c-42d6-a4e7-2a10423c94b8
relation.isAuthorOfPublication.latestForDiscovery0b528961-126c-42d6-a4e7-2a10423c94b8

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
Evaluation of SPECT imaging_a multi-center and multi-vendor phantom study.pdf
Size:
1.03 MB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

ESTeSL - Artigos