| Nome: | Descrição: | Tamanho: | Formato: | |
|---|---|---|---|---|
| 52.26 KB | Adobe PDF |
Orientador(es)
Resumo(s)
In March 2026, a Working Group of 12 scientists from nine countries met at the International Agency for Research on Cancer (IARC) in Lyon, France, to finalise their evaluation of the carcinogenicity of tris(chloropropyl) phosphate (TCPP), butyraldehyde, and cumyl hydroperoxide. TCPP was classified as “probably carcinogenic to humans” (Group 2A) based on the combination of “sufficient” evidence for cancer in experimental animals and “strong” mechanistic evidence in human primary cells. Butyraldehyde was classified as “possibly carcinogenic to humans” (Group 2B) based on “sufficient” evidence for cancer in experimental animals and on “strong” mechanistic evidence in experimental systems. Cumyl hydroperoxide was classified as “possibly carcinogenic to humans” (Group 2B) based on “strong” mechanistic evidence in human primary cells and experimental systems. These assessments will be published in Volume 141 of the IARC Monographs.
Descrição
Palavras-chave
Carcinogenicity Tris(chloropropyl) phosphate Butyraldehyde Cumyl hydroperoxide
Contexto Educativo
Citação
Lachenmeier DW, Arrandale VH, DeMarini DM, Ruksha T, Abdallah MA, Ladeira C, et al. Carcinogenicity of tris(chloropropyl) phosphate, butyraldehyde, and cumyl hydroperoxide. Lancet Oncol. 2026 Mar 27:S1470-2045(26)00168-3. Epub ahead of print.
Editora
Elsevier BV