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Bisphenol A alters transcript levels of biomarker genes for major depressive disorder in vascular endothelial cells and colon cancer cells

2016-06Journal article Restricted access
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dc.contributor.authorRibeiro-Varandas, Edna
dc.contributor.authorPereira, H. Sofia
dc.contributor.authorViegas, Wanda
dc.contributor.authorDelgado, Margarida
dc.date.accessioned2016-06-29T11:04:05Z
dc.date.available2016-06-29T11:04:05Z
dc.date.issued2016-06
dc.description.abstractBisphenol A (BPA) is capable of mimicking endogenous hormones with potential consequences for human health and BPA exposure has been associated with several human diseases including neuropsychiatric disorders. Here, quantitative Real-Time Polymerase Chain Reaction (qRT-PCR) results show that BPA at low concentrations (10 ng/mL and 1 μg/mL) induces differential transcript levels of four biomarker genes for Major Depressive Disorder (MDD) in HT29 human colon adenocarcinona cell line and Human Umbilical Vein Endothelial Cells (HUVEC). These results substantiate increasing concerns of BPA exposure in levels currently detected in humans.pt_PT
dc.identifier.citationRibeiro-Varandas E, Pereira HS, Viegas W, Delgado M. Bisphenol A alters transcript levels of biomarker genes for major depressive disorder in vascular endothelial cells and colon cancer cells. Chemosphere. 2016;153:75-7.pt_PT
dc.identifier.doi10.1016/j.chemosphere.2015.12.085pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.21/6253
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relation.publisherversionhttp://www.sciencedirect.com/science/article/pii/S0045653515305397pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectBisphenol Apt_PT
dc.subjectBPApt_PT
dc.subjectHUVECpt_PT
dc.subjectHT29pt_PT
dc.subjectMDD biomarkerspt_PT
dc.subjectGene transcriptionpt_PT
dc.titleBisphenol A alters transcript levels of biomarker genes for major depressive disorder in vascular endothelial cells and colon cancer cellspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage77pt_PT
oaire.citation.startPage75pt_PT
oaire.citation.titleChemospherept_PT
oaire.citation.volume153pt_PT
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT

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