Logo do repositório
 
Publicação

A call for preregistration of in vitro research: pregistration as a tool to improve reproducibility and transparency

2026-04Artigo científico Acesso embargado
Ver registo simples
datacite.subject.sdg03:Saúde de Qualidade
dc.contributor.authorHeinl, Céline
dc.contributor.authorFranco, Nuno H.
dc.contributor.authorBert, Bettina
dc.contributor.authorSiewert, Katherina
dc.contributor.authorMovia, Dania
dc.contributor.authorAruçi, Edlira
dc.contributor.authorLadeira, Carina
dc.contributor.authorSanin, Ahmed Y.
dc.contributor.authorNeuhaus, Winfried
dc.contributor.authorKahlert, Ulf D.
dc.contributor.authorGhosh, Manosij
dc.contributor.authorThomas, Aurélie
dc.contributor.authorSotiropoulos, Athanassia
dc.date.accessioned2026-04-17T13:12:50Z
dc.date.available2026-04-17T13:12:50Z
dc.date.issued2026-04
dc.descriptionThis publication is based upon work from the working group Quality and Translatability of Science within the COST Action IMPROVE (“3Rs concepts to improve the quality of biomedical science”), CA21139, supported by European Cooperation in Science and Technology (COST, www.cost.eu).
dc.description.abstractBiomedical research, like any other research field, is vulnerable to problems in its planning, execution, documentation, analysis, interpretation, and reporting. These issues can impede the reproducibility of research findings and hinder translation into clinical practice. In addition, there is growing societal pressure to hasten the shift to animal-free research methods. To alleviate the ethical dilemma of using animals in research, the 3Rs principle (replace, reduce, refine) calls for reducing or replacing such experiments wherever possible. Nevertheless, scientific and biomedical research, as well as safeguarding human and environmental health, continue to depend on animal experiments. To apply the 3Rs principles without compromising scientific progress and safety standards, it is imperative to ensure that in vitro methods to replace animal experiments are robust and reliable.eng
dc.identifier.citationHeinl C, Franco NH, Bert B, Siewert K, Movia D, Ladeira C, et al. A call for preregistration of in vitro research: pregistration as a tool to improve reproducibility and transparency. EMBO Rep. 2026 Apr 17. Epub ahead of print.
dc.identifier.doi10.1038/s44319-026-00764-x
dc.identifier.issn1469-3178
dc.identifier.urihttp://hdl.handle.net/10400.21/22801
dc.language.isoeng
dc.peerreviewedyes
dc.publisherSpringer Science and Business Media LLC
dc.relationCOST Action IMPROVE (“3Rs concepts to improve the quality of biomedical science”), CA21139
dc.relation.hasversionhttps://link.springer.com/article/10.1038/s44319-026-00764-x
dc.relation.ispartofEMBO Reports
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectResearch
dc.subjectTransparency
dc.subjectReproducibility
dc.subjectPregistration
dc.titleA call for preregistration of in vitro research: pregistration as a tool to improve reproducibility and transparencyeng
dc.typejournal article
dspace.entity.typePublication
oaire.citation.titleEMBO Reports
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyNameLadeira
person.givenNameCarina
person.identifier144237
person.identifier.ciencia-id801C-1BBA-1D9E
person.identifier.orcid0000-0001-5588-0074
person.identifier.ridJ-2572-2012
person.identifier.scopus-author-id36463788000
relation.isAuthorOfPublication1aef4b60-4197-436b-84ab-80d31cbaed33
relation.isAuthorOfPublication.latestForDiscovery1aef4b60-4197-436b-84ab-80d31cbaed33

Ficheiros

Principais
A mostrar 1 - 1 de 1
Miniatura indisponível
Nome:
A call for preregistration of in vitro research_pregistration as a tool to improve reproducibility and transparency.pdf
Tamanho:
1.57 MB
Formato:
Adobe Portable Document Format
Ver/Abrir
Licença
A mostrar 1 - 1 de 1
Miniatura indisponível
Nome:
license.txt
Tamanho:
4.03 KB
Formato:
Item-specific license agreed upon to submission
Descrição:
Ver/Abrir

Coleções

ESTeSL - Artigos