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Dietary acid load and relationship with albuminuria and glomerular filtration rate in individuals with chronic kidney disease at predialysis state

dc.contributor.authorSilva, Luísa
dc.contributor.authorMoço, Sara Alegria
dc.contributor.authorAntunes, Maria Da Luz
dc.contributor.authorFerreira, Andreia Sousa
dc.contributor.authorMoreira, Ana Catarina
dc.date.accessioned2022-01-27T11:45:44Z
dc.date.available2022-01-27T11:45:44Z
dc.date.issued2022-01
dc.description.abstractThe Western diet, characterized by excessive consumption of animal protein and reduced intake of vegetables and fruits, is also rich in sulfur, chlorine, and organic acids, which are the main sources of dietary acid load. A relationship between dietary acid load, renal function, and progression of chronic kidney disease has been demonstrated. Dietary modifications seem to contribute to a reduction in dietary acid load and are associated with improved outcomes in individuals with chronic kidney disease (CKD). The aim of this paper was to review the existing evidence concerning the association between dietary acid load and renal function in non-dialyzed individuals with CKD. A systematic review was conducted by gathering articles in electronic databases (MEDLINE/PubMed, Scopus, and Web of Science) from January 2018 to May 2021. Dietary acid load and GFR and/or albuminuria were analyzed. A total of 1078 articles were extracted, of which 5 met the inclusion criteria. Only one study found no statistically significant associations between the study variables. The remaining showed a negative association between dietary acid load and renal function. This systematic review confirmed the existence of an association between dietary acid load and renal function, with a high dietary acid load contributing to a decreased renal function.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationSilva L, Moço SA, Antunes ML, Ferreira AS, Moreira AC. Dietary acid load and relationship with albuminuria and glomerular filtration rate in individuals with chronic kidney disease at predialysis state. Nutrients. 2022;14(1):170.pt_PT
dc.identifier.doi10.3390/nu14010170pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.21/14212
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.relation.publisherversionhttps://www.mdpi.com/2072-6643/14/1/170pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectChronic renal insufficiencypt_PT
dc.subjectAcidosispt_PT
dc.subjectWestern dietpt_PT
dc.subjectChronic kidney diseasept_PT
dc.titleDietary acid load and relationship with albuminuria and glomerular filtration rate in individuals with chronic kidney disease at predialysis statept_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue1pt_PT
oaire.citation.startPage170pt_PT
oaire.citation.titleNutrientspt_PT
oaire.citation.volume14pt_PT
person.familyNameAntunes
person.familyNameMoreira
person.givenNameMaria Luz
person.givenNameAna Catarina
person.identifier2087122
person.identifier.ciencia-idB111-6F38-5904
person.identifier.ciencia-idC81E-CC41-DFB0
person.identifier.orcid0000-0003-0942-7601
person.identifier.orcid0000-0001-7031-6738
person.identifier.ridB-8661-2015
person.identifier.scopus-author-id57202291460
person.identifier.scopus-author-id16234261500
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationdce3e466-ad17-4bea-8b95-4a5b9bb22910
relation.isAuthorOfPublicationcdce3e88-b09d-40b9-bad5-29d1d3610f69
relation.isAuthorOfPublication.latestForDiscoverydce3e466-ad17-4bea-8b95-4a5b9bb22910

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