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- Multichannel detector system for surface plasmon resonance biosensorsPublication . Fernandes, Miguel; Fantoni, Alessandro; Soares, Paulo; Lourenço, Paulo; Vieira, ManuelaPhotonic systems are gaining an important role in the field of medical diagnosis due to the achievable high sensitivity and selectivity and low cost, enabling the fabrication of disposable point of care diagnosis systems for multiple pathologies. In this work we present the detector subsystem developed for a multi-channel surface plasmon resonance (SPR) based sensor. The core of the system is a multimode interferometer splitter, fabricated in amorphous silicon, followed by multiple sensitive SPR structures with a functionalized gold layer that modulate the transmitted light waves, in the presence of the biomarker, which are then detected by infrared detectors. For this purpose a highly adaptable detection system based on a InGaAs line CCD device was developed. The IR sensor used in the prototype has 128 (50 x 250 μm) pixels but other formats are supported. To adapt to different light guiding structures, the CCD pixels can be combined forming multiple detection channels. Optical sensor configuration and readout operations are performed trough a USB connection using the SCPI standard. The system includes an analog front end with a programmable gain amplifier and offset adjustment followed by a fast analog to digital converter feeding the data to a STM32 family processor. A computer application was also developed for system configuration and signal readout and storage. The testing results from the complete system are presented. Documentation of the developed system is provided for third party use, all the material generated within this work is available online in a repository.
- Finite-difference time-domain analysis of hydrogenated amorphous silicon and aluminum surface plasmon waveguidesPublication . Lourenço, Paulo; Fantoni, Alessandro; Fernandes, Miguel; Vygranenko, Yuri; Vieira, ManuelaThe large majority of surface plasmon resonance (SPR)-based devices use noble metals, namely gold or silver, in their manufacturing process. These metals present low resistivity, which leads to low optical losses in the visible and near-infrared spectrum ranges. Gold shows high environmental stability, which is essential for long-term operation, and the lower stability of silver can be overcome through the deposition of an alumina layer, for instance. However, their high cost is a limiting factor if the intended target is large-scale manufacturing. This work considers a cost-effective approach through the selection of aluminum as the plasmonic material and hydrogenated amorphous silicon instead of its crystalline counterpart. This SPR structure relies on Fano resonance to improve its response to refractive index deviations of the surrounding environment. Fano resonance is highly sensitive to slight changes of the medium, hence the reason we incorporated this interference phenomenon in the proposed sensing structure. We report the results obtained when conducting finite-difference timedomain algorithm-based simulations on this metal–dielectric–metal structure when the active metal is aluminum, gold, and silver. Then, we evaluate their sensitivity, detection accuracy, and resolution. The obtained results for our proposed sensing structure show good linearity and similar parameter performance as the ones obtained when using gold or silver as plasmonic materials.
- FDTD analysis of Aluminum/a-Si:H surface plasmon waveguidesPublication . Lourenço, Paulo; Fantoni, Alessandro; Fernandes, Miguel; Vygranenko, Yuri; Vieira, ManuelaThe large majority of surface plasmon resonance based devices use noble metals, namely gold or silver, in their manufacturing process. These metals present low resistivity, which leads to low optical losses in the visible and near infrared spectrum ranges. Gold shows high environmental stability, which is essential for long-term operation, and silver's lower stability can be overcome through the deposition of an alumina layer, for instance. However, their high cost is a limiting factor if the intended target is large scale manufacturing. In this work, it is considered a cost-effective approach through the selection of aluminum as the plasmonic material and hydrogenated amorphous silicon instead of its crystalline counterpart. This surface plasmon resonance device relies on Fano resonance to improve its response to refractive index deviations of the surrounding environment. Fano resonance is highly sensitive to slight changes of the medium, hence the reason we incorporated this interference phenomenon in the proposed device. We report the results obtained when conducting Finite-Difference Time Domain algorithm based simulations on this metal-dielectric-metal structure when the active metal is aluminum, gold and silver. Then, we evaluate their sensitivity, detection accuracy and resolution, and the obtained results for our proposed device show good linearity and similar parameter performance as the ones obtained when using gold or silver as plasmonic materials.