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- Instruments to assess gait in individuals with multiple sclerosis: a systematic reviewPublication . Jesus, Maria Margarida de; Pedro, LuisaBackground: Gait impairment is considered a significant cause of disability and is a clinical feature of Multiple Sclerosis. For this reason, their regular assessment is essential for better management and treatment and to evaluate the effectiveness of rehabilitation. Objective: This study aims to know what instruments are available in the literature to assess gait in patients diagnosed with MS. Data Sources and Searches: A complete literature search was conducted in MEDLINE, Web of Science, Embase, and Scopus, following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). The study protocol was registered at the International Prospective Register of Systematic Reviews (PROSPERO). Study Selection: The authors selected studies written in English and representing validation of gait assessment tools exclusively for adults with a diagnosis of MS. Data Extraction and Quality Assessment: Two authors independently extracted the data for reliability, measurement error, validity, and assessed methodological quality using the COnsensus-based standards to select health Measurement Instruments (COSMIN). Data Synthesis and Analysis: All authors performed data synthesis to determine the level of evidence per measurement property per tool.
- The importance of hope for quality of life in patients with multiple sclerosisPublication . Pais-Ribeiro, J. L.; Pedro, LuisaAims: This study intends to describe the importance of hope for the quality of life in patients with multiple sclerosis. Evidence has indicated that Hope is important as a buffer between risk factors, physical and psychological health status, and quality of life for patients with multiple sclerosis. Methods: The study was exploratory and descriptive. Setting: A general Hospital in Lisbon, Portugal. Participants: 280 patients with Multiple Sclerosis. We explore the relationship between Hope and Quality of Life. The instruments used are the Multiple Sclerosis Quality of Life scale (MSQol-54) and the Hope Scale. Results: The correlation between the Hope Scale and the domains of MSQOL-54: Physical Health (r=0.24, p<0.05), Physical Role Limitations (r=0.25, p<0.05), Emotional Role Limitations (r=0.35, p<0.05), Pain (r=0.28, p<0.05),Well-being (r=0.48, p<0.01), Energy (r=0.42, p<0.01), Health in General (r=0.41, p<0.01), Social Function (r=0.45, p<0.01), Cognitive Function (r=0.28, p<0.05), Health Distress (r=0.52, p<0.01), Overal Qol (r=0.49, p<0.01), Sexual function (r=0.33, p<0.05), Change in Health (r=-0.17, p<0.05), and Satisfaction with sexual function (r=0.33, p<0.05). Conclusions: There is a statistically significant correlation between the variables, suggesting that hope can play an important role in the quality of life of patients with multiple sclerosis, especially in domains such as the perception of well-being, health in general, and social function, and distress.
- Well-being and disease severity of multiple sclerosis patients following a physical activity programPublication . Pedro, Luisa; Pais-Ribeiro, José Luís; Páscoa Pinheiro, JoãoABSTRACT - Introduction: Multiple sclerosis (MS) is a chronic disease of the central nervous system that mainly affects young adults, promoting a great impact on functionality. Fatigue is a very common symptom, associated with multiple impairments in sensitivity, muscle activity, neuromotor control, balance, cognition, and problem-solving ability. MS leads to strong functional restrictions, particularly in the context of daily living activities, as well as in patient participation. Objective: To understand the implications of a self-regulation program in the perception of well-being and mental health in MS patients. Methods: A set of exercises was implemented for use in daily activities, supported by different studies with MS patients. Patients were asked to classify the severity of their disease and to use the Mental Health Inventory (MHI-38), at the beginning (time A) and at the end (time B) of the self-regulation program. We used the Statistical Package for the Social Sciences (SPSS) version 25. A non-parametric statistical hypothesis test (Wilcoxon test) was used to analyze the variables. Results: The mean age was 44 years old, with patients between the ages of 20 and 58. 58.3% were women, 37.5% were currently married, 67% were retired and the mean level of education was 12.5 years. The correlation between the perception of disease severity and psychological well-being before the self-regulation program (r = 0.26, p < 0.05) and after the intervention (r = 0.37, p < 0.01) suggests a low to moderate correlation. Conclusion: The implementation of the self-regulatory model, through the promotion of physical activity in patients with MS, had a positive impact on clinical rehabilitation, well-being, and perception of disease severity of these people.