Browsing by Author "Henriques, M."
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- Energy-Aware Routing And Grooming For IP Transport Over WDM MLR NetworksPublication . Henriques, M.; Pinho, Pedro; Teixeira, AntónioIn this work a mixed integer optimization linear programming (MILP) model was applied to mixed line rate (MLR) IP over WDM and IP over OTN over WDM (with and without OTN grooming) networks, with aim to reduce network energy consumption. Energy-aware and energy-aware & short-path routing techniques were used. Simulations were made based on a real network topology as well as on forecasts of traffic matrix based on statistical data from 2005 up to 2017. Energy aware routing optimization model on IPoWDM network, showed the lowest energy consumption along all years, and once compared with energy-aware & short-path routing, has led to an overall reduction in energy consumption up to 29%, expecting to save even more than shortest-path routing. © 2014 IEEE.
- How important is personality in neurological patient' quality of life perception?Publication . Meneses, Rute; Pais-Ribeiro, José Luís; Pedro, Luísa; Silva, Isabel; Cardoso, Helena; Mendonça, Denisa; Vilhena, Estela; Abreu, M.; Henriques, M.; Melo, V.; Martins, Ana; Martins-da-Silva, AntónioIn the last decades, the value of research on neurological patients’ quality of life (QOL) has become unquestionable. In this context, most studies focus on the relationship between patients’ QOL and their sociodemographic and/or clinical and/or modifiable psychosocial characteristics. They give us information regarding the sociodemographic and clinical profile most prone to low QOL reports and also on ways to improve patients’ QOL (e.g., targeting their selfesteem). Nevertheless, little is known about the role nonmodifiable psychosocial variables can have on patients’ QOL perception. Consequently, the aim of the present study is to explore the relationship between QOL and personality in neurological patients.
- Poly(DL-lactic acid) scaffolds adsorbed with minocycline and voriconazole: a new pathway towards infection containmentPublication . Zegre, Miguel; Henriques, M.; Santos, C.; Ribeiro, I. A.; Caetano, Liliana Aranha; Gonçalves, Lídia M.; Bettencourt, Ana F.Bone infection (osteomyelitis): burden as a clinical complication of orthopedic surgeries. Controlled antimicrobial release systems: treat and prevent osteomyelitis. Biomaterials based on porous scaffolds: local administration of high concentration of drugs; no systemic toxicity; extended time. Scaffolds in bone tissue engineering: a combination of bioresorbable polymers with bioactive bioglasses; present biodegradability and biosafety; suitable microenvironment and structure; favor osteogenic differentiation and cell growth. Co-encapsulation of drugs: advantageous means for administration of drugs; novel strategy directed to the co-delivery of two antimicrobials (voriconazole and minocycline).
- Release kinetic model and antimicrobial activity of an innovative minocycline and voriconazole co-delivery systemPublication . Zegre, Miguel; Henriques, M.; Ribeiro, I. A.; Caetano, Liliana Aranha; Gonçalves, Lídia M.; Bettencourt, Ana F.Purpose and Strategy: Development of a new local drug-delivery system aiming at bone infection and the modulation of the polymicrobial activity; simultaneous delivery of minocycline and voriconazole, antibacterial and antifungal agents, respectively; polylactide (PDLLA) scaffolds functionalized with collagen and bioglass, osteogenic enhancers.