Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.21/2498
Título: Occupational exposure to Aflatoxin B1 in Portuguese swine farms
Autor: Viegas, Susana
Veiga, Luísa
Figueiredo, Paula
Almeida, Ana
Carolino, Elisabete
Viegas, Carla
Palavras-chave: Environmental health
Occupational health
Aflatoxin B1
Data: Fev-2013
Citação: Viegas S, Veiga L, Figueiredo P, Almeida A, Carolino E, Viegas C. Occupational exposure to Aflatoxin B1 in Portuguese swine farms. In SHO 2013 - International Symposium on Occupational Safety and Hygiene, Guimarães (Portugal), 14th-15th February 2013. Oral presentation.
Resumo: Aflatoxins were first isolated about 40 years ago afier outbreaks of disease and death in turkeys and cancer in rainbow trout fed with rations formulated from peanut and cottonseed meals. These toxins are secondary metabolites produced under certain conditions of temperature, p14 and humidity predominantiy by Aspergilius flavus and Aspergilius parasiticus fungi species. Among 18 different types of aflatoxins identified, major members are aflatoxin B1, B2, G1 and G2. Aflatoxin B1 (AFB1) is normaily predominant in cultures as well as in food products. AFB1 was shown to be genotoxic and a potent hepatocarcinogen. This mycotoxin is metabolized by the mixed function oxidase system to a number of hydroxylated metabolites including the 8,9-epoxide. The latter is considered to be the ultimate carcinogen that reacts with cellular deoxyribonucleic acid (DNA) and proteins to form covalent adducts.
Peer review: yes
URI: http://hdl.handle.net/10400.21/2498
Versão do Editor: http://www.sposho.pt/sho2013/sho2013_program_final.pdf
Aparece nas colecções:ESTeSL - Comunicações

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