Publication
Minimisation of acquisition time in a TOF PET/CT scanner without compromising image quality
| dc.contributor.author | Oliveira, Joana | |
| dc.contributor.author | Parafita, Rui | |
| dc.contributor.author | Branco, Susana | |
| dc.date.accessioned | 2017-12-23T22:03:04Z | |
| dc.date.available | 2017-12-23T22:03:04Z | |
| dc.date.issued | 2017-09 | |
| dc.description.abstract | Introduction - Significant improvements have been made in Positron Emission Tomography/Computed Tomography (PET/CT) to enhance the image quality, namely, the development of time-of-flight (TOF) technology. This technique is useful to localize the emission point of the beta plus-emitter (β+) radiopharmaceutical inside the body, allowing better lesion contrast, especially for large patients, improving structural details and leading to a short scan time. The main goal of this study is to verify the shortest acquisition time per bed position, in a TOF PET scanner, without compromising the image quality, in both phantom and clinical imaging. Methods - For that purpose, images of a torso NEMA phantom were acquired with different acquisition times per bed position (30, 45, 60, 80 and 120 s) in a TOF PET/CT scanner (GEMINI TF 16, Philips), using Gallium-68 (68Ga) citrate. Clinical images were also acquired of an aleatory patient (male, 64 y) with 68Ga-prostate specific membrane antigen (68Ga-PSMA). Image quality parameters, such as signal-to-noise ratio (SNR), noise, contrast, contrast-to-noise ratio (CNR), contrast recovery coefficient (CRC) and quantification in terms of standardized uptake value (SUV) were acquired. Results - The increased contrast and CRC in larger spheres and with longer acquisition times produces an increase on the noise, leading to a decrease in SNR and CNR. In phantom imaging, SUVmax varied between 1.1 and 1.6 for background (normal uptake) and between 2.1 and 8.0 for spheres (abnormal uptake). A strong correlation was found for both SUVmax and SUVmean between the different acquisition times (R>0.7). Inpatient imaging, spleen showed higher SNR, contrast, noise, and CNR than liver. Median SUVmax was 7.1 for liver, 9.8 for spleen and 1.8 for bone. Conclusions - A time between 45 and 60 s per bed position is proposed for future clinical practices, allowing schedule more scans per day, contributing to an optimization of protocols without compromising the image quality. | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.citation | Oliveira J, Parafita R, Branco S. Minimisation of acquisition time in a TOF PET/CT scanner without compromising image quality. In: PRS 2017 – Conference "Proteção Radiológica na Saúde 2017", Instituto Superior Técnico (Lisboa), 27-29 de setembro de 2017. | pt_PT |
| dc.identifier.uri | http://hdl.handle.net/10400.21/7785 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.relation.publisherversion | http://www.ctn.tecnico.ulisboa.pt/prs2017/BookAbstracts-PRS2017-v2.pdf | pt_PT |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | pt_PT |
| dc.subject | PET/CT | pt_PT |
| dc.subject | TOF | pt_PT |
| dc.subject | 68Ga | pt_PT |
| dc.subject | Acquisition time | pt_PT |
| dc.subject | Image quality | pt_PT |
| dc.title | Minimisation of acquisition time in a TOF PET/CT scanner without compromising image quality | pt_PT |
| dc.type | conference object | |
| dspace.entity.type | Publication | |
| oaire.citation.conferencePlace | Lisboa | pt_PT |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | conferenceObject | pt_PT |
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