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National recommendations for the safe handling of hazardous drugs by pharmacy technicians in Portugal: a modified delphi study

2026-04Artigo científico Acesso embargado
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datacite.subject.sdg03:Saúde de Qualidade
dc.contributor.authorSilva, Vítor
dc.contributor.authorValeiro, Carolina
dc.contributor.authorAlves, Ana
dc.contributor.authorCosta, Ana
dc.contributor.authorCosta-Veiga, Ana
dc.contributor.authorReis, Ana Rita
dc.contributor.authorSimões, Ana Rita
dc.contributor.authorSilva, Ana
dc.contributor.authorAndrade, Anabela
dc.contributor.authorOliveira, Andreia
dc.contributor.authorMarques, André
dc.contributor.authorPerpétuo, Carla
dc.contributor.authorPereira, Cátia
dc.contributor.authorCarriço, Cristina
dc.contributor.authorVieira, Elisabete
dc.contributor.authorMoreira, fernando
dc.contributor.authorSantos, Joana
dc.contributor.authorVilar, Joana
dc.contributor.authorJoaquim, João
dc.contributor.authorValadares, Luís
dc.contributor.authorBaeta, Maria
dc.contributor.authorCouras, Mariana
dc.contributor.authorRamires, Milene
dc.contributor.authorSilva, Nuno Miguel
dc.contributor.authorPereira, Olívia R.
dc.contributor.authorGuerra, Paula Bustorff
dc.contributor.authorAlexandre, Pedro
dc.contributor.authorPinto, Rafaela
dc.contributor.authorPelota, Ricardo
dc.contributor.authorGomes, Sofia Alves
dc.contributor.authorGrilo, Sofia Roque
dc.contributor.authorVieira, Sofia
dc.contributor.authorSequeira, Susana
dc.contributor.authorGuedelha, Tânia
dc.contributor.authorFreire, Tiago
dc.contributor.authorOliveira, Vânia
dc.contributor.authorMatos, Cristiano
dc.date.accessioned2026-05-15T08:52:02Z
dc.date.available2026-05-15T08:52:02Z
dc.date.issued2026-04
dc.descriptionAssociação Portuguesa de Licenciados em Farmácia (APLF) has received an unrestricted Education grant from Beckton Dickinson® to develop the project “Portuguese recommendations for the safety of pharmacy technicians handling chemotherapy”. This work received financial support from the PT national funds (FCT/MECI, Fundação para a Ciência e Tecnologia, and Ministério da Educação, Ciência e Inovação) through the project UID/50006—Laboratório Associado para a Química Verde—Tecnologias e Processos Limpos, under the project UID/06157/2025 (https://doi.org/10.54499/UID/06157/2025) - Research Centre for Active Living and Wellbeing (LiveWell).
dc.description.abstractBackground: Occupational exposure to hazardous drugs is a recognised occupational risk in hospital pharmacy practice. Although international guidelines are available, the implementation is heterogeneous, and there are currently no formally endorsed national recommendations regarding the safety of pharmacy technicians in Portugal. Objective: To develop consensus-based national recommendations for the safe handling of hazardous drugs by pharmacy technicians in Portugal. Methods: A modified Delphi study was conducted involving 43 invited experts from Portuguese hospital pharmacies. Fifty-eight statements were evaluated using a 0-10 agreement scale through one formal quantitative round, followed by a structured online consensus validation meeting and documentary confirmation. Consensus was predefined as a median score >7. Results: Thirty-six experts completed Round 1 (response rate 83.7%). All 58 statements voted on in Round 1 achieved consensus, with median scores of 10 for all recommendations and 98% of ratings ≥7. Following consolidation and merging procedures, the final set comprised 55 recommendations. The final recommendations were organised into five domains: occupational health surveillance, engineering controls and PPE, preparation technique and quality assurance, administrative safeguards, and environmental contamination and waste management. Conclusions: This study establishes the first structured national consensus on the safety of hazardous drug handling for pharmacy technicians in Portugal. The resulting framework supports harmonisation of institutional practices, strengthens occupational risk governance, and provides a foundation for future implementation and evaluation studies.eng
dc.identifier.citationSilva V, Valeiro C, Alves A, Costa A, Costa-Veiga A, Reis AR, et al. National recommendations for the safe handling of hazardous drugs by pharmacy technicians in Portugal: a modified delphi study. J Oncol Pharm Pract. 2026 Apr 24:10781552261441848. Epub ahead of print.
dc.identifier.doi10.1177/10781552261441848
dc.identifier.issn1078-1552
dc.identifier.issn1477-092X
dc.identifier.urihttp://hdl.handle.net/10400.21/22880
dc.language.isoeng
dc.peerreviewedyes
dc.publisherSAGE Publications
dc.relation.hasversionhttps://journals.sagepub.com/doi/10.1177/10781552261441848
dc.relation.ispartofJournal of Oncology Pharmacy Practice
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectHazardous drugs
dc.subjectDelphi
dc.subjectHospital pharmacy
dc.subjectSafe handling
dc.titleNational recommendations for the safe handling of hazardous drugs by pharmacy technicians in Portugal: a modified delphi studyeng
dc.typejournal article
dspace.entity.typePublication
oaire.citation.titleJournal of Oncology Pharmacy Practice
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyNameCosta-Veiga
person.givenNameAna
person.identifier.ciencia-idEB1D-EC27-3302
person.identifier.orcid0000-0002-5183-9872
relation.isAuthorOfPublication031eaeb7-3a62-4c01-b411-06e9701e4d06
relation.isAuthorOfPublication.latestForDiscovery031eaeb7-3a62-4c01-b411-06e9701e4d06

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