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Abstract(s)
Objetivo: Estudar o impacto da técnica Double Inversion Recovery (DIR), em Ressonância Magnética (RM), na rotina clínica de patologias cerebrais, através de uma revisão sistemática da literatura. Métodos: Foi efetuada uma pesquisa bibliográfica em duas bases de dados (PubMed e Directory of Open Access Journals) através das palavras-chaves DIR, MRI e brain, cuja pesquisa foi realizada até 30 de Abril de 2020. Previamente, foram estabelecidos os critérios de inclusão e exclusão e, posteriormente, foi realizada uma extração manual dos dados. Foram excluídos os estudos duplicados, pediátricos, veterinários e post-mortem, de mulheres grávidas, publicados antes de 2000 e em outras línguas que não português, inglês e espanhol. Os artigos que aplicam a técnica DIR, sua análise e comparação com outras técnicas em RM foram submetidos a uma validação do risco de viés através Cochrane Risk of Bias Tool e a uma discussão dos seus resultados. Resultados: Da pesquisa bibliográfica foram identificados 143 artigos, dos quais 5 foram eliminados por serem duplicados, 83 foram excluídos com base nos dados fornecidos no resumo e após aplicados os critérios de exclusão, 55 foram analisados na íntegra e somente 26 artigos foram incluídos no estudo. Conclusão: Sobre a técnica DIR foram encontrados resultados divergentes entre si. Destaca-se o impacto da técnica em estudos de esclerose múltipla (EM). Compreende-se que a técnica DIR é útil e considerada, maioritariamente, mais sensível para o estudo de EM, epilepsia, alzheimer e glioblastomas. Contudo, propõem-se mais estudos após otimização da técnica.
ABSTRACT - Purpose: To study the impact of the technique Double Inversion Recovery (DIR), in Magnetic Resonance, in the clinical routine of cerebral pathologies, through a systematic review of the literature. Methods: The bibliographic search was performed on two databases (PubMed e Directory of Open Access Journals) using the keywords DIR, MRI and brain until April 30, 2020. Previously, inclusion and exclusion criteria were established and, subsequently, data were extracted manually. The exclusion criteria were duplicate, pediatric, veterinary and post-mortem studies, studies in pregnant women, published before 2000 and in other languages than Portuguese, English, and Spanish. The articles that apply the DIR technique, its analysis, and comparison with other techniques in Magnetic Resonance were submitted to an assessment of the risk of bias through the Cochrane Risk of Bias Tool and to a discussion of its results. Results: From the search 143 articles were identified, of which 5 were eliminated for being duplicated, 83 were excluded based on data abstraction and after exclusion criteria application, 55 were analyzed by full text and only 26 articles were selected. Conclusion: Different results were found about technique DIR. The impact of this technique in studies of multiple sclerosis is highlighted. DIR is useful in studies of multiple sclerosis, epilepsy, Alzheimer and glioblastomas. However, further studies with an optimized technique are proposed.
ABSTRACT - Purpose: To study the impact of the technique Double Inversion Recovery (DIR), in Magnetic Resonance, in the clinical routine of cerebral pathologies, through a systematic review of the literature. Methods: The bibliographic search was performed on two databases (PubMed e Directory of Open Access Journals) using the keywords DIR, MRI and brain until April 30, 2020. Previously, inclusion and exclusion criteria were established and, subsequently, data were extracted manually. The exclusion criteria were duplicate, pediatric, veterinary and post-mortem studies, studies in pregnant women, published before 2000 and in other languages than Portuguese, English, and Spanish. The articles that apply the DIR technique, its analysis, and comparison with other techniques in Magnetic Resonance were submitted to an assessment of the risk of bias through the Cochrane Risk of Bias Tool and to a discussion of its results. Results: From the search 143 articles were identified, of which 5 were eliminated for being duplicated, 83 were excluded based on data abstraction and after exclusion criteria application, 55 were analyzed by full text and only 26 articles were selected. Conclusion: Different results were found about technique DIR. The impact of this technique in studies of multiple sclerosis is highlighted. DIR is useful in studies of multiple sclerosis, epilepsy, Alzheimer and glioblastomas. However, further studies with an optimized technique are proposed.
Description
Mestrado em Radiações Aplicadas às Tecnologias da Saúde. - Área de Especialização: Imagem por Ressonância Magnética
Keywords
Ressonância magnética Double Inversion Recovery Cérebro Magnetic resonance Brain
Citation
Pereira MJ. Efeito da técnica Double Inversion Recovery (DIR) por ressonância magnética na caracterização de patologias cerebrais: revisão sistemática [dissertation]. Lisboa: Escola Superior de Tecnologia da Saúde de Lisboa/Instituto Politécnico de Lisboa; 2020.
Publisher
Instituto Politécnico de Lisboa, Escola Superior de Tecnologia da Saúde de Lisboa