Publication
Vitamin D in dysphagic patients who have undergone endoscopic gastrostomy for long-term enteral feeding
dc.contributor.author | Santos, Carla Adriana | |
dc.contributor.author | Nunes, Gonçalo | |
dc.contributor.author | Barata, Ana Teresa | |
dc.contributor.author | Fonseca, Jorge | |
dc.date.accessioned | 2021-04-28T19:03:24Z | |
dc.date.available | 2024-04-28T00:30:22Z | |
dc.date.issued | 2021-01 | |
dc.description.abstract | Objective: Vitamin D plays a major role in biological processes. Its deficiency is associated with increased morbidity and mortality. Patients who have undergone endoscopic gastrostomy (PEG) present with protein-energy malnutrition, and may be at risk for Vitamin D deficiency, due to their age, less sunlight exposure, and lower dietary intake. We aimed to determine the prevalence of hypovitaminosis D in PEG patients, its change under PEG-feeding, and its relationship with serum proteins and risk factors for Vitamin D deficiency. Methods: This was a prospective observational study, over 4 weeks, after gastrostomy. Data were collected at the initial PEG procedure (T0), and after 4 weeks (T1). Initial evaluation included age, gender, underlying disorder, NRS-2002, BMI, serum albumin, transferrin, and Vitamin D. At T1 we assessed Vit. D, albumin, and transferrin. Vitamin D was performed with Electrochemiluminescence through Elecsys 2010 assay. Patients were fed with blended homemade meals. Results: 200 patients (118 males), 22-92 years of age, were studied. There were initial low values for Vit. D (181), albumin (96), transferrin (121), and BMI (124). A correlation was found between Vit. D and serum albumin (r=0.49, p=0.005) but not with transferrin (r=0.26, p=0.195). At T1 the subgroup who had Vit. D levels assessed (n=48) was part of the initial study group maintained low levels of Vitamin D despite nutritional intervention. Conclusion: We recommend systematic Vitamin D supplementation of PEG-fed patients using homemade meals or at least screening for hypovitaminosis D as a routine part of their care. | pt_PT |
dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
dc.identifier.citation | Santos CA, Nunes G, Barata AT, Fonseca J. Vitamin D in dysphagic patients who have undergone endoscopic gastrostomy for long-term enteral feeding. Gastroenterol Hepatol. 2021;44(1):13-9. | pt_PT |
dc.identifier.doi | 10.1016/j.gastrohep.2020.05.016 | pt_PT |
dc.identifier.uri | http://hdl.handle.net/10400.21/13243 | |
dc.language.iso | eng | pt_PT |
dc.peerreviewed | yes | pt_PT |
dc.publisher | Elsevier | pt_PT |
dc.relation.publisherversion | https://www.sciencedirect.com/science/article/abs/pii/S0210570520302478?via%3Dihub | pt_PT |
dc.subject | Disfagia | pt_PT |
dc.subject | Dysphagia | pt_PT |
dc.subject | GEP | pt_PT |
dc.subject | Gastrostomy | pt_PT |
dc.subject | Nutrición | pt_PT |
dc.subject | Nutrition | pt_PT |
dc.subject | PEG | pt_PT |
dc.subject | Vitamin D | pt_PT |
dc.subject | Vitamina D | pt_PT |
dc.title | Vitamin D in dysphagic patients who have undergone endoscopic gastrostomy for long-term enteral feeding | pt_PT |
dc.type | journal article | |
dspace.entity.type | Publication | |
oaire.citation.endPage | 19 | pt_PT |
oaire.citation.issue | 1 | pt_PT |
oaire.citation.startPage | 13 | pt_PT |
oaire.citation.title | Gastroenterología y Hepatología | pt_PT |
oaire.citation.volume | 44 | pt_PT |
rcaap.rights | openAccess | pt_PT |
rcaap.type | article | pt_PT |
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