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Influence of adipose tissue in myocardial counts using attenuation correction in SPECT/CT imaging: study in phantom

2019-04Journal article Restricted access
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dc.contributor.authorGalvão, Tiago
dc.contributor.authorRoberto, João
dc.contributor.authorFigueiredo, Sérgio
dc.contributor.authorCarolino, Elisabete
dc.contributor.authorMarques, Andreia
dc.contributor.authorPintão, Sophia
dc.contributor.authorVieira, Lina Oliveira
dc.date.accessioned2019-05-27T16:02:25Z
dc.date.available2019-05-27T16:02:25Z
dc.date.issued2019-04
dc.description.abstractMyocardial perfusion imaging (MIP) with single photon emission computed tomography is one of the most accurate procedures for the detection of coronary artery disease. Tissue attenuation artifacts are a significant limitation of MIP, especially in obese patients. CT-based attenuation correction (AC) is widely used to undermine these artifacts. The objective of this study was to evaluate the influence of an adipose tissue equivalent in the total myocardial counts after AC in SPECT/CT imaging. To accomplish this a Heart Thorax Phantom was filled with 99m TcO4-(simulating the uptake of 99m Tc-tetrofosmin in the cardiac walls and liver) for SPECT/CT imaging using an additional layer of 100% lipid fat and a torso phantom. The acquired data were reconstructed with Filtered Back Projection (FBP), iterative algorithms without AC (IRNC) and iterative algorithms with AC (IRAC) for posterior evaluation of total cardiac wall count (Anterior, Inferior, Lateral and Septal). There was a significant reduction in total mean counts of the lateral and septal walls, with the addition of a layer of fat and the torso phantom, when FBP and IRNC reconstructions were applied (p ≤ 0,05) which may have been caused by tissue attenuation artifacts. The addition of a layer of fat and of the torso phantom, directly increased the total mean counts of the septal, lateral and inferior walls, when IRAC reconstruction was used (p ≤ 0,05) suggesting a benefit in the use of AC in larger body habitus. In conclusion, the adipose tissue equivalent directly influenced the total myocardium counts when AC methods were applied, and further research is advised.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationGalvão T, Roberto J, Figueiredo S, Carolino E, Marques A, Vieira L, et al. Influence of adipose tissue in myocardial counts using attenuation correction in SPECT/CT imaging: study in phantom. In: ENBENG 2019 – Proceedings of the 6th IEEE Portuguese Meeting on Bioengineering, Instituto Superior de Engenharia de Lisboa (ISEL), Portugal, February 22-23, 2019. Article no. 8692521.pt_PT
dc.identifier.doi10.1109/ENBENG.2019.8692521pt_PT
dc.identifier.isbn9781538685068
dc.identifier.urihttp://hdl.handle.net/10400.21/10075
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherIEEEpt_PT
dc.relation.publisherversionhttps://ieeexplore.ieee.org/document/8692521pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectNuclear medicinept_PT
dc.subjectSingle photon emission computed tomographypt_PT
dc.subjectIterative methodspt_PT
dc.subjectParticle beamspt_PT
dc.subjectPhantomspt_PT
dc.subjectCoronary artery diseasept_PT
dc.subjectCt-based attenuation correctionspt_PT
dc.subjectMyocardial perfusion imagingpt_PT
dc.titleInfluence of adipose tissue in myocardial counts using attenuation correction in SPECT/CT imaging: study in phantompt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage4pt_PT
oaire.citation.startPage1pt_PT
person.familyNameCarolino
person.familyNameVieira
person.givenNameElisabete
person.givenNameLina Oliveira
person.identifier.ciencia-id1216-EFA3-1E0F
person.identifier.ciencia-idD316-5085-2DE0
person.identifier.orcid0000-0003-4165-7052
person.identifier.orcid0000-0002-7109-6535
person.identifier.ridF-1012-2015
person.identifier.ridP-7426-2015
person.identifier.scopus-author-id25821697000
person.identifier.scopus-author-id55258594400
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication77930d39-ed34-44dc-a4a6-9bf833e5e688
relation.isAuthorOfPublication0b528961-126c-42d6-a4e7-2a10423c94b8
relation.isAuthorOfPublication.latestForDiscovery0b528961-126c-42d6-a4e7-2a10423c94b8

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