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Magnesium, insulin resistance and body composition in healthy postmenopausal women

2004-10Journal article Open access
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dc.contributor.authorLaires, Maria J.
dc.contributor.authorMoreira, Helena
dc.contributor.authorMonteiro, Cristina P.
dc.contributor.authorSardinha, Luís
dc.contributor.authorLimão, F.
dc.contributor.authorVeiga, Luísa
dc.contributor.authorGonçalves, Alice
dc.contributor.authorFerreira, A.
dc.contributor.authorBicho, Manuel
dc.date.accessioned2014-01-03T21:16:03Z
dc.date.available2014-01-03T21:16:03Z
dc.date.issued2004-10
dc.description.abstractObjective: This study was conducted to determine the association between magnesium (Mg), body composition and insulin resistance in 136 sedentary postmenopausal women, 50 to 77 years of age. Methods: Diabetics, hypertensives and women on hormonal replacement therapy were excluded and the remaining 74 were divided according to BMI≥25 (obese: OG) and BMI<25 kg/m2 (non-obese: NOG). Nutritional data disclosed that intakes were high for protein and saturated fat, low for carbohydrates, polyunsaturated fat and Mg and normal for the other nutrients, according to recommended dietary allowances (RDA). Mg values in red blood cells (RBC-Mg) and plasma (P-Mg), were determined, as were fasting glucose, and insulin levels, Homeostasis Model Assessment (HOMA), body mass index (BMI), body fat percent (BF %), abdominal fat (AF) and free fat mass (FFM). Results: RBC-Mg values were low in both groups when compared with normal values. There were significant differences in body composition parameters, HOMA and insulin levels, with higher basal insulin levels in OG. RBC-Mg was directly correlated with insulin, HOMA and FFM in both groups, according to Pearson correlations. HOMA in OG was also directly correlated with BMI, FFM and AF. In NOG, HOMA was only correlated with FFM. The low RBC-Mg levels observed were probably due to low Mg intake and to deregulation of factors that control Mg homeostasis during menopause. Conclusions: Both Mg deficit and obesity may independently lead to a higher risk for insulin resistance and cardiovascular disease.por
dc.identifier.citationLaires MJ, Moreira H, Monteiro CP, Sardinha L, Limão F, Veiga L, et al. Magnesium, insulin resistance and body composition in healthy postmenopausal women. J Am Coll Nutr. 2004;23(5):510S-513S.por
dc.identifier.issn1541-1087
dc.identifier.urihttp://hdl.handle.net/10400.21/3064
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherTaylor & Francispor
dc.relation.publisherversionhttp://www.tandfonline.com/doi/abs/10.1080/07315724.2004.10719391?tab=permissions#tabModulepor
dc.subjectBlood glucosepor
dc.subjectBody compositionpor
dc.subjectCardiovascular diseasepor
dc.subjectDiet recordspor
dc.subjectErythrocytespor
dc.subjectInsulinpor
dc.subjectMagnesiumpor
dc.subjectNutrition policypor
dc.subjectObesitypor
dc.subjectPostmenopausepor
dc.subjectReference valuespor
dc.titleMagnesium, insulin resistance and body composition in healthy postmenopausal womenpor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage513Spor
oaire.citation.startPage510Spor
oaire.citation.titleJournal of the American College of Nutritionpor
oaire.citation.volume23por
person.familyNameVeiga
person.givenNameLuisa
person.identifier.ciencia-id9413-918D-DB0E
person.identifier.orcid0000-0003-1153-8343
person.identifier.ridL-2730-2013
person.identifier.scopus-author-id8318978600
rcaap.rightsrestrictedAccesspor
rcaap.typearticlepor
relation.isAuthorOfPublicationaac1914a-275f-4be2-819d-ab41d356b45a
relation.isAuthorOfPublication.latestForDiscoveryaac1914a-275f-4be2-819d-ab41d356b45a

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