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Generational changes in lung function in adults from several world regions: results from the Burden of Obstructive Lung Disease study

2026-09Artigo científico Acesso embargado
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datacite.subject.sdg03:Saúde de Qualidade
dc.contributor.authorMa, Jixuan
dc.contributor.authorBurney, Peter G.
dc.contributor.authorMannino, David M.
dc.contributor.authorJanson, Christer
dc.contributor.authorGíslason, Thorarinn
dc.contributor.authorObaseki, Daniel O.
dc.contributor.authorJõgi, Rain
dc.contributor.authorSantofimio, Valentina Quintero
dc.contributor.authorPotts, James
dc.contributor.authorRashid, Abdul
dc.contributor.authorErhabor, Gregory E.
dc.contributor.authorNielsen, Rune
dc.contributor.authorKocabas, Ali
dc.contributor.authorNafees, Asaad
dc.contributor.authorAhmed, Rana
dc.contributor.authorDenguezli, Meriam
dc.contributor.authorBarbara, Cristina
dc.contributor.authorCardoso, Joao
dc.contributor.authorDias, Maria Hermínia Monteiro Brites
dc.contributor.authorRodrigues, Fátima
dc.contributor.authorAgarwal, Dhiraj
dc.contributor.authorJuvekar, Sanjay
dc.contributor.authorFranssen, Frits M.
dc.contributor.authorSeemungal, Terence
dc.contributor.authorMortimer, Kevin
dc.contributor.authorEl Biaze, Mohammed
dc.contributor.authorMahesh, Padukudru Anand
dc.contributor.authorKoul, Parvaiz
dc.contributor.authorStudnicka, Michael
dc.contributor.authorAmaral, Andre F.
dc.date.accessioned2026-09-22T11:36:50Z
dc.date.available2026-09-22T11:36:50Z
dc.date.issued2026-09
dc.descriptionThe HUST Outstanding Young Visiting Scholars Development Project (no grant number) supported this work, and the BOLD study baseline was funded by a Wellcome Trust grant (085790/Z/08/Z). The study funder was not involved in the study design, data collection, analysis, and interpretation, report writing, or imposing any restrictions on publication.
dc.description.abstractThis study estimated birth cohort effects on lung function using BOLD (Burden of Obstructive Lung Disease) data from 28,569 adults born between 1902 and 1976 across 41 sites in 34 countries. Forced vital capacity (FVC), forced expiratory volume in 1 s (FEV1) and the FEV1/FVC increased across successive birth cohorts in both high-income countries (HICs) and low- and middle-income countries (LMICs), with mean values rising steadily with later birth year. In fully adjusted models, FVC increased by 21.4 mL, FEV1 by 24.6 mL and FEV1/FVC by 0.25% per birth year. These positive associations were consistent across sex, smoking status, and country-income subgroups (HICs and LMICs).eng
dc.identifier.citationMa J, Burney PG, Mannino DM, Janson C, Gíslason T, Dias HB, et al. Generational changes in lung function in adults from several world regions: results from the Burden of Obstructive Lung Disease study. Thorax. 2026 Sep 18:thorax-2026-225173. Epub ahead of print.
dc.identifier.doi10.1136/thorax-2026-225173
dc.identifier.issn0040-6376
dc.identifier.issn1468-3296
dc.identifier.urihttp://hdl.handle.net/10400.21/23170
dc.language.isoeng
dc.peerreviewedyes
dc.publisherBMJ
dc.relation.hasversionhttps://thorax.bmj.com/content/early/2026/09/18/thorax-2026-225173
dc.relation.ispartofThorax
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectCOPD epidemiology
dc.subjectLung function
dc.subjectBurden of Obstructive Lung Disease
dc.titleGenerational changes in lung function in adults from several world regions: results from the Burden of Obstructive Lung Disease studyeng
dc.typejournal article
dspace.entity.typePublication
oaire.citation.titleThorax
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyNameDias
person.givenNameMaria Hermínia Monteiro Brites
person.identifier.ciencia-idE211-FB1B-04E3
person.identifier.orcid0000-0003-1257-8734
person.identifier.ridAFL-8310-2022
person.identifier.scopus-author-id55671930200
relation.isAuthorOfPublicationb7b7e7d9-83b2-4d63-9176-4ed73cf6b939
relation.isAuthorOfPublication.latestForDiscoveryb7b7e7d9-83b2-4d63-9176-4ed73cf6b939

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