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Characterization of the Tubulin-binding cofactor B in Toxoplasma gondii, a zoonotic parasite

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Tubulin cofactors participate in the folding, dimerization, and dissociation pathways of the tubulin dimer, being implicated in the control of tubulin proteostasis and consequently in the control of microtubule (MT) dynamics in vivo. We identified a gene coding for a Tubulin cofactor B in the T. gondii genome and characterized its protein (tgTBCB) in the tachyzoite stage.

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Tubulin Toxoplasma gondii

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Delgado I, Francisco S, Santos D, Zúquete S, Leitão A, Soares H, Nolasco S. Characterization of the Tubulin-binding cofactor B in Toxoplasma gondii, a zoonotic parasite. In: 2021 ASCB Annual Meeting abstracts. Mol Biol Cell. 2021;32(22):poster 819.

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American Society for Cell Biology

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