| Name: | Description: | Size: | Format: | |
|---|---|---|---|---|
| 11.15 MB | Adobe PDF |
Authors
Advisor(s)
Abstract(s)
Com o presente Trabalho Final de Mestrado – Projeto de AVAC aplicado à Indústria
Farmacêutica, com ênfase no Controlo e Instrumentação, pretende-se estudar e aplicar
as técnicas de climatização, refrigeração, controlo e monitorização adequadas a uma
indústria exigente no que concerne a qualidade de ar interior.
Dado o controlo de qualidade rígido que recai sobre os produtos derivados da indústria
farmacêutica, a exigência e rigor refletem-se em todo o processo de produção, desde a
matéria-prima, até às condições ambiente em que se desenrola o processo e se armazena
o produto final. Sobre a indústria farmacêutica recaem rígidas normas e diretivas, o que
se espelha também na necessidade de um controlo e monitorização detalhados sobre o
AVAC.
Pode dizer-se que, no caso particular da indústria farmacêutica, o AVAC tem um papel
crítico na cadeia de produção, ficando em segundo plano o conforto do utilizador que é
usualmente o foco dos sistemas de AVAC.
O nível de qualidade de ar no interior de uma sala limpa depende diretamente do sistema
de AVAC, sendo vital a monitorização e controlo das condições interiores para que se
garanta o cumprimento de todas as exigências. Estas exigências são estabelecidas por
normas como a ISO 14644 ou a GMP – Good Manufacturing Practices.
Com o presente trabalho, pretende-se desenvolver o sistema de AVAC e controlo de uma
instalação destinada à produção farmacêutica, projetando a solução técnica mais
adequada e um sistema de controlo que apresente garantias de monitorização e controlo.
Dada a dimensão do laboratório, não seria vantajosa a produção de água quente e fria,
optou-se assim por um sistema de expansão direta, com recurso a uma bomba de calor
reversível para o tratamento de ar na UTAN. A unidade será 100% ar novo com vista à
mitigação de contaminação da sala limpa por ar recirculado. Quanto ao SGTC, os
equipamentos estarão integrados e serão monitorizados com recurso ao equipamento de
campo, garantindo o controlo rigoroso das condições do ar interior e de parâmetros como
o diferencial de pressões entre os espaços.
With the present Master Degree Project - HVAC Project applied to the Pharmaceutical Industry, emphasizing Control and Instrumentation, it is intended to study and apply the appropriate techniques of HVAC, refrigeration, control and monitoring to a demanding industry regarding the quality of indoor air. Given the strict quality control of products derived from the pharmaceutical industry, the requirement and rigor is reflected in the entire production process, from the raw material, to the ambient conditions under which the process is carried out and the final product is stored. The pharmaceutical industry has strict standards and directives, which also reflects the need for detailed control and monitoring of HVAC. In the particular case of the pharmaceutical industry, HVAC can be said to play a critical role in the production chain, leaving behind the user comfort that is usually the focus of HVAC systems. The level of air quality inside a clean room depends directly on the HVAC system. Monitoring and control of indoor conditions is vital to ensure that all requirements are met. These requirements are set by standards such as ISO 14644 or GMP - Good Manufacturing Practices. The present work intends to develop the HVAC and control system of a facility for pharmaceutical production, addressing the peripheral and central issues, designing the most appropriate technical solution and a control system that offers guarantees of monitoring and control. Given the size of the laboratory, central production of hot and cold water for air conditioning would not be advantageous, so it was opted for a direct expansion system, using a reversible heat pump for air treatment at AHU. The unit will be 100% fresh air to mitigate clean room contamination by recirculated air. As for BMS, the equipment will be integrated and monitored using field equipment, ensuring strict control of indoor air conditions and parameters such as pressure differential between spaces.
With the present Master Degree Project - HVAC Project applied to the Pharmaceutical Industry, emphasizing Control and Instrumentation, it is intended to study and apply the appropriate techniques of HVAC, refrigeration, control and monitoring to a demanding industry regarding the quality of indoor air. Given the strict quality control of products derived from the pharmaceutical industry, the requirement and rigor is reflected in the entire production process, from the raw material, to the ambient conditions under which the process is carried out and the final product is stored. The pharmaceutical industry has strict standards and directives, which also reflects the need for detailed control and monitoring of HVAC. In the particular case of the pharmaceutical industry, HVAC can be said to play a critical role in the production chain, leaving behind the user comfort that is usually the focus of HVAC systems. The level of air quality inside a clean room depends directly on the HVAC system. Monitoring and control of indoor conditions is vital to ensure that all requirements are met. These requirements are set by standards such as ISO 14644 or GMP - Good Manufacturing Practices. The present work intends to develop the HVAC and control system of a facility for pharmaceutical production, addressing the peripheral and central issues, designing the most appropriate technical solution and a control system that offers guarantees of monitoring and control. Given the size of the laboratory, central production of hot and cold water for air conditioning would not be advantageous, so it was opted for a direct expansion system, using a reversible heat pump for air treatment at AHU. The unit will be 100% fresh air to mitigate clean room contamination by recirculated air. As for BMS, the equipment will be integrated and monitored using field equipment, ensuring strict control of indoor air conditions and parameters such as pressure differential between spaces.
Description
Trabalho final de mestrado para obtenção do grau de mestre em Engenharia Mecânica
Keywords
Indústria farmacêutica Pharmaceutical industry AVAC HVAC Controlo Control Instrumentação Instrumentation Qualidade do ar interior Indoor air quality
Citation
MORAIS, Luís Carlos Alves - Projeto de AVAC aplicado à indústria farmacêutica, com ênfase no controlo e instrumentação. Lisboa: Instituto Superior de Engenharia de Lisboa, 2019. Dissertação de mestrado.
Publisher
Instituto Superior de Engenharia de Lisboa