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Formaldehyde's genotoxicity effects in pathology anatomy technologists and medical pathologists

2011-09Conference object Open access
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dc.contributor.authorLadeira, Carina
dc.contributor.authorViegas, Susana
dc.contributor.authorPrista, J.
dc.contributor.authorGomes, Manuel C.
dc.contributor.authorBrito, Miguel
dc.date.accessioned2011-11-28T11:20:41Z
dc.date.available2011-11-28T11:20:41Z
dc.date.issued2011-09
dc.description.abstractFormaldehyde (FA) had been considered to be carcinogenic by the International Agency for Research on Cancer (group1), on the basis of sufficient evidence both in humans and in experimental animals, making it a subject of major environmental concern, especially in the occupational context. Manifold in vitro studies clearly indicated that FA is genotoxic, inducing various genotoxic effects in proliferating cultured mammalian cells. Cytokinesis-blocked micronucleus (CBMN) assay is used extensively in molecular epidemiology, and the chromosomal alterations most reported and studied by the CBMN are: micronucleus (MN), nucleoplasmic bridges (NPB) and nuclear buds (NBUDs). The pathology anatomy laboratories are work places that manipulate routinely FA and pathology anatomy technologists and pathologists contact daily with this chemical compound particularly in the macroscopic exam and grossing procedures. The aim of this study was to identify genotoxicity biomarkers in the set workers groups, such as micronucleus (MN), nucleoplasmic bridges (NPB) and nuclear buds (NBUD) in peripheral blood lymphocytes.por
dc.identifier.citationLadeira C, Viegas S, Prista J, Gomes MC, Brito M. Formaldehyde's genotoxicity effects in pathology anatomy technologists and medical pathologists. In The European Environmental Mutagens Society, Oslo (Norway), 15th to 18th September 2011. Poster.por
dc.identifier.urihttp://hdl.handle.net/10400.21/652
dc.language.isoengpor
dc.peerreviewedyespor
dc.subjectAnatomia patológicapor
dc.subjectSaúde ocupacionalpor
dc.subjectMeio laboratorialpor
dc.subjectFormaldeídopor
dc.subjectBiomarcador tumoralpor
dc.titleFormaldehyde's genotoxicity effects in pathology anatomy technologists and medical pathologistspor
dc.typeconference object
dspace.entity.typePublication
person.familyNameLadeira
person.familyNameViegas
person.familyNameBrito
person.givenNameCarina
person.givenNameSusana
person.givenNameMiguel
person.identifier144237
person.identifier248817
person.identifier.ciencia-id801C-1BBA-1D9E
person.identifier.ciencia-idA919-7318-63DC
person.identifier.ciencia-id231F-F341-7E93
person.identifier.orcid0000-0001-5588-0074
person.identifier.orcid0000-0003-1015-8760
person.identifier.orcid0000-0001-6394-658X
person.identifier.ridJ-2572-2012
person.identifier.ridI-4053-2012
person.identifier.ridA-7970-2016
person.identifier.scopus-author-id36463788000
person.identifier.scopus-author-id35270591500
person.identifier.scopus-author-id35224551000
rcaap.rightsopenAccesspor
rcaap.typeconferenceObjectpor
relation.isAuthorOfPublication1aef4b60-4197-436b-84ab-80d31cbaed33
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relation.isAuthorOfPublication.latestForDiscovery1aef4b60-4197-436b-84ab-80d31cbaed33

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