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Characterization of plasmonic effects in AuNP+rGO composite as a sensing layer for a low-cost lab-on-chip biosensor

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dc.contributor.authorFantoni, Alessandro
dc.contributor.authorStojkovic, Vladan
dc.contributor.authorFernandes, Miguel
dc.contributor.authorLouro, Paula
dc.contributor.authorVieira, Manuela
dc.contributor.authorAlegria, Elisabete
dc.contributor.authorDa Costa Ribeiro, Ana Paula
dc.contributor.authorCarvalho, Ana
dc.contributor.authorAlmeida, M. Gabriela
dc.date.accessioned2019-12-12T11:22:06Z
dc.date.available2019-12-12T11:22:06Z
dc.date.issued2019
dc.descriptionEste trabalho foi financiado pelo Concurso Anual para Projetos de Investigação, Desenvolvimento, Inovação e Criação Artística (IDI&CA) 2018 do Instituto Politécnico de Lisboa. Código de referência IPL/2018/aSiPhoto_ISEL
dc.description.abstractThis work deals with the production of a low-cost disposable biosensor for point of care applications. The proposed sensor is a plasmonic structure based on the Localized Surface Plasmon Resonance (LSPR) interaction of metal nanoparticles (MNPs), embedded into a matrix of reduced Graphene Oxide (rGO). After proper functionalization with selective antibodies (Ab), the efficiency of light extinction is controlled by slight changes of the refractive coefficient induced by the concentration of biomarkers trapped by the antibodies on the sensor surface. This work reports a study about the applicability of rGO as a support for gold nanoparticles (AuNPs) for preparing the functionalized LSPR sensing layer. AuNPs are prepared with an economic and eco-friendly method using phytochemicals present in tea extract at room temperature, while a modified Hummer’s method is used to synthesize rGO. The resulting AuNPs-rGO composites are studied in terms of UV-VIS spectroscopy spectral light transmission and plasmonic resonance. The overall analysis is supported by simulation results, obtained by Mie analysis, about the LSPR effect in AuNPs-rGO and its dependence on the biomarker concentration.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationFANTONI, Alessandro; [et al] – Characterization of plasmonic effects in AuNP+rGO composite as a sensing layer for a low-cost lab-on-chip biossensor. In Proceedings of PhotonIcs & Electromagnetics Research Symposium — Spring (PIERS — SPRING). Rome, Italy: SPRING, 2019. ISSN 1559-9450. Pp. 4180- 4186pt_PT
dc.identifier.issn1559-9450
dc.identifier.urihttp://hdl.handle.net/10400.21/10840
dc.language.isoengpt_PT
dc.publisherSpringpt_PT
dc.relationPTDC/NAN-OPT/31311/2017 - FCTpt_PT
dc.relationSFRH/BPD/102217/2014 - FCTpt_PT
dc.relationProjeto financiado no âmbito do Concurso de Projetos de Investigação, Desenvolvimento, Inovação & Criação Artística (IDI&CA) financiados pelo Instituto Politécnico de Lisboa.IPL/2018/aSiPhoto_ISELpt_PT
dc.subjectPlasmonic effectspt_PT
dc.subjectAuNP+rGOpt_PT
dc.subjectLab-on-chippt_PT
dc.subjectBiosensorpt_PT
dc.titleCharacterization of plasmonic effects in AuNP+rGO composite as a sensing layer for a low-cost lab-on-chip biosensorpt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferencePlace17–20 June 2019 - Rome, Italypt_PT
oaire.citation.endPage4186pt_PT
oaire.citation.startPage4180pt_PT
oaire.citation.title2019 PhotonIcs & Electromagnetics Research Symposiumpt_PT
person.familyNameFantoni
person.familyNameFernandes
person.familyNameLouro
person.familyNameVieira
person.familyNameAlegria
person.familyNameda Costa Ribeiro
person.familyNameAlmeida
person.givenNameAlessandro
person.givenNameMiguel
person.givenNamePaula
person.givenNameManuela
person.givenNameElisabete
person.givenNameAna Paula
person.givenNameGabriela
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rcaap.rightsclosedAccesspt_PT
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