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TNBS-induced colitis in rodents: preliminary results of a chronic model

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Abstract(s)

Chronic inflammatory disease of the gastrointestinal (GI) tract characterized by recurrent ulceration. Treatment of inflammatory bowel disease induce and maintain the patient in remission However do not modify or reverse the underlying pathogenic mechanism. Nonclinical studies for emerging therapeutic strategies. Aim of the study: Evaluate the efficacy of new drugs in inflammatory bowel disease through an animal model of TNBS-induced chronic colitis.

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IDI&CA_COLITIS/2019 - Pharmacological modulation of inflammation associated with inflammatory bowel disease: a model of chronic experimental colitis

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Inflammatory bowel disease Ulcerative colitis Crohn disease Animal model IDI&CA_COLITIS/2019

Citation

Silva IJ, Solas J, Sousa M, Modesto R, Mateus V, Pinto R. TNBS-induced colitis in rodents: preliminary results of a chronic model. In: II Seminário de Investigação Aplicada em Farmácia, ESTeSL, 7 de dezembro de 2019.

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