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Linkage between electronic prescribing data and pharmacy claims records to determine primary adherence: the case of antihypertensive therapy in the Lisbon and Tagus Valley Region, Portugal

2023-03Journal article Open access
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dc.contributor.authorCoelho, André
dc.date.accessioned2022-10-17T11:53:08Z
dc.date.available2024-10-17T00:30:24Z
dc.date.issued2023-03
dc.description.abstractBackground: Hypertension (HT) is highly prevalent and a major risk factor for cardiovascular disease. Over 42% of Portuguese adults have HT. Even though the benefits of antihypertensive (AHT) drugs have been demonstrated, HT control remains inadequate. One major reason is that patients often fail to take their medications as prescribed. This paper aims to determine primary adherence to AHT therapy in newly diagnosed and treated hypertensive patients in Primary Health Care (PHC) units of Lisbon and Tagus Valley Health Region. Methods: This study reports data from a population-based, retrospective, cohort study from patients diagnosed with HT in PHC units of Lisbon and Tagus Valley Region from 1 January to 31 March 2011, with no prior use of AHT drugs. The primary adherence rate was expressed as the number of claims records/total number of prescriptions records. Data were collected from SIARS for each patient during a 2-year period. Results: Overall primary adherence rate was 58.5%, increasing with age. Rates were higher for men, living in the Lisbon Metropolitan Area and diagnosed with uncomplicated HT. Drugs acting on the renin-angiotensin system had the highest rates, increasing for fixed-dose combinations and diminishing with the increase of cost for the patient. Conclusions: Overall, almost 1 out of 2 prescribed AHT drugs were not dispensed. Until this study, little was known in Portugal about primary adherence. Our findings imply that the potential benefits of AHT therapy cannot be fully realized in this population.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationCoelho A. Linkage between electronic prescribing data and pharmacy claims records to determine primary adherence: the case of antihypertensive therapy in the Lisbon and Tagus Valley Region, Portugal. Fam Pract. 2023;40(2):248-54.pt_PT
dc.identifier.doi10.1093/fampra/cmac109pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.21/15032
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherOxford University Presspt_PT
dc.relation.publisherversionhttps://academic.oup.com/fampra/advance-article-abstract/doi/10.1093/fampra/cmac109/6732248?redirectedFrom=fulltextpt_PT
dc.subjectAntihypertensive therapypt_PT
dc.subjectMedication adherencept_PT
dc.subjectPrimary adherencept_PT
dc.subjectPortugalpt_PT
dc.subjectLisboa e Vale do Tejopt_PT
dc.titleLinkage between electronic prescribing data and pharmacy claims records to determine primary adherence: the case of antihypertensive therapy in the Lisbon and Tagus Valley Region, Portugalpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage254pt_PT
oaire.citation.issue2pt_PT
oaire.citation.startPagecmac109pt_PT
oaire.citation.startPage248pt_PT
oaire.citation.titleFamily Practicept_PT
oaire.citation.volume40pt_PT
person.familyNameFerreira Ramos Coelho
person.givenNameAndré Filipe
person.identifier.ciencia-id291E-1AC6-86FA
person.identifier.orcid0000-0003-1872-8131
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicatione00e9fd8-697d-4e70-acd3-e5a5169360ed
relation.isAuthorOfPublication.latestForDiscoverye00e9fd8-697d-4e70-acd3-e5a5169360ed

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