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Biological monitoring of aflatoxin (AFB1) in workers of swine and poultry production

2012-06Conference object Open access
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dc.contributor.authorViegas, Susana
dc.contributor.authorVeiga, Luísa
dc.contributor.authorAlmeida, Ana
dc.contributor.authorFigueiredo, Paula
dc.contributor.authorCarolino, Elisabete
dc.contributor.authorViegas, Carla
dc.date.accessioned2012-11-14T16:03:08Z
dc.date.available2012-11-14T16:03:08Z
dc.date.issued2012-06
dc.description.abstractAlthough a great body of literature exists concerning the ingestion of food contaminated with aflatoxin, there are still few studies regarding mycotoxin inhalation in occupational settings. Since mycotoxins are relatively non-volatile, inhalation exposure is cause by inhalation of airborne fungal particulates or fungi-contaminated substrates that contain aflatoxin. We intend to know if there is occupational exposure to aflatoxin in Portuguese poultry and swine production. A total of 19 individuals (11 swine; 8 poultry) agreed and provided blood samples during the course of this investigation. Measurement of AFB1 was performed by ELISA. The samples were treated with pronase (Merck), wash in a Column C18 and purification was made with immunoaffinity columns (R.biopharma), specific for AFB1. It was applied statistical test (Mann-Whitney) to verified statistical difference in AFB1 results between the two settings. Results varied with concentrations from <LOD to 5.96 ng ml-1 (Poultry: <LOD – 3.67 ng ml-1; Swine: <LOD -5.96 ng ml-1. There wasn’t found statistical difference between the two occupational settings, however, results reveal a tendency for poultry workers have higher aflatoxin values, probably because poultry activities are promoter of particles exposure. Only women’s in both settings have results <LOD. These results are probably due to differences in the activities performed. Exposure to air and dust containing aflatoxin by inhalation should be consider a route of exposure in both settings.por
dc.identifier.citationViegas S, Veiga L, Almeida A, Figueiredo P, Carolino E, Viegas C. Biological monitoring of aflatoxin (AFB1) in workers of swine and poultry production. Toxicol Lett. 2012;211 Suppl:S49.por
dc.identifier.issn0378-4274
dc.identifier.urihttp://hdl.handle.net/10400.21/1928
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherElsevierpor
dc.relation.publisherversionhttp://www.sciencedirect.com/science/article/pii/S0378427412003001por
dc.subjectSaúde ambientalpor
dc.subjectSaúde ocupacionalpor
dc.subjectAflatoxinaspor
dc.subjectAviáriopor
dc.subjectEnvironmental healthpor
dc.subjectOccupational healthpor
dc.subjectAflatoxin B1por
dc.subjectPoultrypor
dc.subjectBiological monitoringpor
dc.subjectSwine productionpor
dc.titleBiological monitoring of aflatoxin (AFB1) in workers of swine and poultry productionpor
dc.typeconference object
dspace.entity.typePublication
oaire.citation.titleToxicology Letterspor
person.familyNameViegas
person.familyNameVeiga
person.familyNameCarolino
person.familyNameViegas
person.givenNameSusana
person.givenNameLuisa
person.givenNameElisabete
person.givenNameCarla
person.identifier248817
person.identifier.ciencia-idA919-7318-63DC
person.identifier.ciencia-id9413-918D-DB0E
person.identifier.ciencia-id1216-EFA3-1E0F
person.identifier.ciencia-idEE1E-C639-D70F
person.identifier.orcid0000-0003-1015-8760
person.identifier.orcid0000-0003-1153-8343
person.identifier.orcid0000-0003-4165-7052
person.identifier.orcid0000-0002-1545-6479
person.identifier.ridI-4053-2012
person.identifier.ridL-2730-2013
person.identifier.ridF-1012-2015
person.identifier.ridB-7217-2013
person.identifier.scopus-author-id35270591500
person.identifier.scopus-author-id8318978600
person.identifier.scopus-author-id25821697000
person.identifier.scopus-author-id55443609700
rcaap.rightsopenAccesspor
rcaap.typeconferenceObjectpor
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relation.isAuthorOfPublicationaac1914a-275f-4be2-819d-ab41d356b45a
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