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Implementation of a newborn screening for sickle cell disease, at the Hospital Materno Infantil Dr Manuel Pedro Azancot de Menezes, Angola

2023-12Conference object Open access
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dc.contributor.authorBrito, Miguel
dc.contributor.authorInusa, Baba P.
dc.contributor.authorGinete, Catarina
dc.contributor.authorMendes, Manuela
dc.contributor.authorAfonso, Roberto
dc.contributor.authorValentim, Isabel
dc.contributor.authorSiatembo, Adriano
dc.contributor.authorVasconcelos, Jocelyne Neto
dc.date.accessioned2024-04-03T11:45:07Z
dc.date.available2024-04-03T11:45:07Z
dc.date.issued2023-12
dc.description.abstractSickle Cell Disease (SCD) is a hereditary disease, and a worldwide public health problem, with a higher incidence in sub-Saharan Africa, where the prevalence is very high (about 80%). SCD prevalence can reach 3,3 % in Angola, while carriers of the sickle cell trait account for more than 25% of the population. The early identification of patients and their follow-up in consultation are an added value for the reduction of morbidity and mortality of children with SCD. The implementation of early infant screening and follow-up programs for children with SCD showed excellent results in increasing the survival of these children. With this project we intend to implement a Newborn screening in Hospital Materno Infantil Dr Manuel Pedro Azancot de Menezes, a referral of the main maternity in Angola, located in Luanda, the country capital, that could be replicated in other hospitals, giving training to the health professionals, and to the laboratory technicians, to diagnose the SCD patients. The objective of this project is to establish a neonatal screening for SCD at a main Hospital in Angola, contributing to reducing under-5 mortality and supporting pediatric follow-up consultations of children diagnosed with SCD. Specific aims include: recording the data and medical history of babies diagnosed with SCD up to 5 years of age at regular appointments; estimating the prevalence of SCD in the municipality of Camama, Luanda; and evaluating the costs of neonatal screening and early interventions in Angola, by supporting a registry of SCD.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationBrito M, Inusa BP, Ginete C, Mendes M, Afonso R, Valentim I, et al. Implementation of a newborn screening for sickle cell disease, at the Hospital Materno Infantil Dr Manuel Pedro Azancot de Menezes, Angola. In: 65th ASH – American Society of Hematology Annual Meeting and Exposition 2023, San Diego (USA), December 9-12, 2023. Blood. 2023;142 Suppl 1:5300.pt_PT
dc.identifier.doi10.1182/blood-2023-179803pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.21/17247
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.relation.publisherversionhttps://ash.confex.com/ash/2023/webprogram/start.htmlpt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectSickle cell diseasept_PT
dc.subjectChildrenpt_PT
dc.subjectPediatric hospitalpt_PT
dc.subjectAngolapt_PT
dc.titleImplementation of a newborn screening for sickle cell disease, at the Hospital Materno Infantil Dr Manuel Pedro Azancot de Menezes, Angolapt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferencePlaceSan Diegopt_PT
person.familyNameBrito
person.familyNameHonrado Ginete
person.givenNameMiguel
person.givenNameAna Catarina
person.identifier.ciencia-id231F-F341-7E93
person.identifier.ciencia-id8715-F62E-1E0F
person.identifier.orcid0000-0001-6394-658X
person.identifier.orcid0000-0002-2334-782X
person.identifier.ridA-7970-2016
person.identifier.scopus-author-id35224551000
rcaap.rightsopenAccesspt_PT
rcaap.typeconferenceObjectpt_PT
relation.isAuthorOfPublication4252d8e0-800c-4d67-8b13-0b711d860669
relation.isAuthorOfPublicationdfb2fbba-17ff-42fb-905a-fcfc8f326e1c
relation.isAuthorOfPublication.latestForDiscovery4252d8e0-800c-4d67-8b13-0b711d860669

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