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Advisor(s)
Abstract(s)
Four groups of 71 subjects 47 with body mass index (BMI) between 30 and 35 (27 Male (M1) and 20 Female (F1)) and 24 with BMI above 35 ( 13 Male (M2) and 11 Female (F2)) who underwent stress-rest , SPECT MPI of a two day protocol, by EANM guideline protocol, with and without the incorporation of the Attenuation correction by computed tomography (CTAC), for stress and rest separately. For perfusion percentage quantifications, the 5 walls model of the left ventricle (LV) was used: anterior (ANT), lateral (LAT), inferior (INF), septal (SEP) and apical (API), using the QGS/QPSTM software. For statistical evaluation, it was used the Friedman test. Statistically significant differences were found in comparison of studies with and without attenuation correction (AC) for: F1 in stress and rest studies respectively for LAT (p=0.006 and p=0.034), INF (p=0.000 and p=0.000) and in rest study for SEP (p=0.044) LV walls; F2 group of stress and rest studies respectively for INF (p=0.001 and p=0.008) walls; M1 group of stress and rest study respectively for LAT (p=0.000 and p=0.000), INF (p=0.000 and p=0.000) SEP (p=0.003 and p=0.001) walls and just in rest study for API (p=0.045) LV walls; M2 group of stress and rest studies respectively for INF (p=0.000 and p=0.000), LAT (p=0.020 and p=0.014) and in stress study for SEP (p=0.003) LV walls. The influence of CT-AC is bigger within the groups with BMI between 30 and 35.
Description
Este trabalho foi financiado pelo Concurso Anual para Projetos de Investigação, Desenvolvimento, Inovação e Criação Artística (IDI&CA) 2016 do Instituto Politécnico de Lisboa. Código de referência: IPL/2016/CardiaCor_ESTeSL
Keywords
Myocardial perfusion imaging Computed tomography Attenuation correction Obesity Body mass index IPL/2016/CardiaCor_ESTeSL
Citation
Stakhiv O, Melo I, Clarke M, Carolino E, Vieira L, Sousa E, et al. Influence of computed tomography attenuation correction in myocardial perfusion imaging, in obese patients: classification by sex and body mass index. In: SYMCOMP 2017, 3rd International Conference on Numerical and Symbolic Computation: developments and applications. APMTAC – Associação Portuguesa de Mecânica Teórica, Aplicada e Computacional; 2017. p. 283-92.