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The role of illness perceptions on medication nonadherence among patients with hypertension: a multicenter study in Indonesia

2022-09Journal article Open access
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dc.contributor.authorAlfian, Sofa D.
dc.contributor.authorAnnisa, Nurul
dc.contributor.authorPerwitasari, Dyah A.
dc.contributor.authorCoelho, André
dc.contributor.authorAbdulah, Rizky
dc.date.accessioned2022-10-17T10:54:48Z
dc.date.available2022-10-17T10:54:48Z
dc.date.issued2022-09
dc.description.abstractIntroduction: Nonadherence to antihypertensive medications is recognized as a significant cause of treatment failure. Therefore, identifying its underlying factors, particularly from the patient's perspective, is essential for developing tailored intervention strategies. The objective of this study was to evaluate the associations between different domains of illness perception and medication nonadherence among patients with hypertension in Indonesia. Patients and methods: A multicenter cross-sectional study was conducted among patients with hypertension aged 18 years old and older who were using antihypertensive medications in the last 3 months in the community health centers in the three cities in Indonesia. The different domains of illness perception (e.g., consequences, timeline, personal control, treatment control, identity, concerns, comprehension, and emotional response) and medication nonadherence were assessed using a validated Brief Illness Perceptions Questionnaire (BIPQ) and Medication Adherence Report Scale (MARS), respectively. A logistic regression analysis was conducted to evaluate the associations between the different domains of illness perception and medication nonadherence adjusting for confounders. The odds ratios (ORs) and 95% confidence intervals (CIs) were reported. Results: A total of 440 participants were included, 41.8% reported nonadherence to antihypertensive medications. The majority of the participants were females (64.3%) and aged between 60 and 69 years old (39.5%). The treatment control (OR: 0.80, 95% confidence interval: 0.7-10.90), patient's comprehension of hypertension (OR: 0.89, 95% CI: 0.820-0.97), and patient's emotions (OR: 0.93, 95% CI: 0.88-0.99) were significantly associated with medication nonadherence. No significant associations were observed between the other domains of illness perception and medication nonadherence. Conclusion: Different dimensions of illness perception were associated with non-adherence to antihypertensive medications. Educational interventions should be developed based on patient's perception of their illness.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationAlfian SD, Annisa N, Perwitasari DA, Coelho A, Abdulah R. The role of illness perceptions on medication nonadherence among patients with hypertension: a multicenter study in Indonesia. Front Pharmacol. 2022;13:985293.pt_PT
dc.identifier.doi10.3389/fphar.2022.985293pt_PT
dc.identifier.pmid36225558
dc.identifier.urihttp://hdl.handle.net/10400.21/15030
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherFrontiers Mediapt_PT
dc.relation.publisherversionhttps://www.frontiersin.org/articles/10.3389/fphar.2022.985293/fullpt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectAntihypertensive medicationpt_PT
dc.subjectIllness perceptionpt_PT
dc.subjectMedication adherencept_PT
dc.subjectLow-income to middle-income countriespt_PT
dc.subjectIndonesiapt_PT
dc.titleThe role of illness perceptions on medication nonadherence among patients with hypertension: a multicenter study in Indonesiapt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.startPage985293pt_PT
oaire.citation.titleFrontiers in Pharmacologypt_PT
oaire.citation.volume13pt_PT
person.familyNameFerreira Ramos Coelho
person.givenNameAndré Filipe
person.identifier.ciencia-id291E-1AC6-86FA
person.identifier.orcid0000-0003-1872-8131
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicatione00e9fd8-697d-4e70-acd3-e5a5169360ed
relation.isAuthorOfPublication.latestForDiscoverye00e9fd8-697d-4e70-acd3-e5a5169360ed

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