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Human biomonitoring: an overview on biomarkers and their application in occupational and environmental health

2016-12Journal article Open access
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dc.contributor.authorLadeira, Carina
dc.contributor.authorViegas, Susana
dc.date.accessioned2017-01-16T12:16:01Z
dc.date.available2017-01-16T12:16:01Z
dc.date.issued2016-12
dc.description.abstractHuman biomonitoring (HBM) is a scientifically developed approach for assessing human exposures to natural and synthetic compounds from environment, occupation, and lifestyle. It relies on the measurement of particular substances or biological breakdown products, known as metabolites, in human tissues and/or fluids, and also includes the study of their effects and the possible influence of individual susceptibility as response modulators. HBM is a growing area of knowledge used for exposure and risk assessment in environmental and occupational health, and its importance has been increasing as a result of advancements in the ability to measure greater numbers of chemicals in the human body and tissues. In order to achieve this purpose, HBM focuses on the use of biomarkers as measurable indicators of early changes in biological systems. However, because data interpretation requires caution, it is strongly recommended that the interpretation of HBM results be combined with air monitoring data or pharmacokinetic modelling in order to better understand exposure sources and the metabolism of chemicals.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationLadeira C, Viegas S. Human biomonitoring: an overview on biomarkers and their application in occupational and environmental health. Biomonitoring. 2016;3(1):15-24.pt_PT
dc.identifier.doi10.1515/bimo-2016-0003pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.21/6707
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherDe Gruyterpt_PT
dc.relation.publisherversionhttps://www.degruyter.com/view/j/bimo.2016.3.issue-1/bimo-2016-0003/bimo-2016-0003.xmlpt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/pt_PT
dc.subjectHuman biomonitoringpt_PT
dc.subjectBiomarkerspt_PT
dc.subjectGenotoxicitypt_PT
dc.subjectExposurept_PT
dc.subjectEnvironmental healthpt_PT
dc.subjectOccupational healthpt_PT
dc.titleHuman biomonitoring: an overview on biomarkers and their application in occupational and environmental healthpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage24pt_PT
oaire.citation.issue1pt_PT
oaire.citation.startPage15pt_PT
oaire.citation.titleBiomonitoringpt_PT
oaire.citation.volume3pt_PT
person.familyNameLadeira
person.familyNameViegas
person.givenNameCarina
person.givenNameSusana
person.identifier144237
person.identifier248817
person.identifier.ciencia-id801C-1BBA-1D9E
person.identifier.ciencia-idA919-7318-63DC
person.identifier.orcid0000-0001-5588-0074
person.identifier.orcid0000-0003-1015-8760
person.identifier.ridJ-2572-2012
person.identifier.ridI-4053-2012
person.identifier.scopus-author-id36463788000
person.identifier.scopus-author-id35270591500
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication1aef4b60-4197-436b-84ab-80d31cbaed33
relation.isAuthorOfPublication13115332-43f7-4048-a8a5-2f2b855a8c92
relation.isAuthorOfPublication.latestForDiscovery13115332-43f7-4048-a8a5-2f2b855a8c92

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