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Orientador(es)
Resumo(s)
Current methods struggle to reconstruct and visualize the genomic relationships of large numbers of bacterial genomes. GrapeTree facilitates the analyses of large numbers of allelic profiles by a static "GrapeTree Layout" algorithm that supports interactive visualizations of large trees within a web browser window. GrapeTree also implements a novel minimum spanning tree algorithm (MSTree V2) to reconstruct genetic relationships despite high levels of missing data. GrapeTree is a stand-alone package for investigating phylogenetic trees plus associated metadata and is also integrated into EnteroBase to facilitate cutting edge navigation of genomic relationships among bacterial pathogens.
Descrição
Palavras-chave
Bacterial genome GrapeTree Genoma bacteriano
Contexto Educativo
Citação
ZHEMIN, Zhou; [et al] – GrapeTree visualization of core genomic relationships among 100,000 bacterial pathogens. Genome Research. ISSN 1088-9051. Vol. 28, N.º 9 (2018), pp. 1395-1404
Editora
Cold Spring Harbor Laboratory Press