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GrapeTree: visualization of core genomic relationships among 100,000 bacterial pathogens

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Autores

Zhou, Zhemin
Alikhan, Nabil-Fareed
Sergeant, Martin

Orientador(es)

Resumo(s)

Current methods struggle to reconstruct and visualize the genomic relationships of large numbers of bacterial genomes. GrapeTree facilitates the analyses of large numbers of allelic profiles by a static "GrapeTree Layout" algorithm that supports interactive visualizations of large trees within a web browser window. GrapeTree also implements a novel minimum spanning tree algorithm (MSTree V2) to reconstruct genetic relationships despite high levels of missing data. GrapeTree is a stand-alone package for investigating phylogenetic trees plus associated metadata and is also integrated into EnteroBase to facilitate cutting edge navigation of genomic relationships among bacterial pathogens.

Descrição

Palavras-chave

Bacterial genome GrapeTree Genoma bacteriano

Contexto Educativo

Citação

ZHEMIN, Zhou; [et al] – GrapeTree visualization of core genomic relationships among 100,000 bacterial pathogens. Genome Research. ISSN 1088-9051. Vol. 28, N.º 9 (2018), pp. 1395-1404

Projetos de investigação

Unidades organizacionais

Fascículo

Editora

Cold Spring Harbor Laboratory Press

Licença CC

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