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Finefix® fixation in histopathological samples with macroscopic, histochemistry and immunohistochemistry assessment: a systematic literature review

2024-03Conference object Open access
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dc.contributor.authorFilipe, João
dc.contributor.authorSilva, Mariana
dc.contributor.authorMonteiro, Natacha
dc.contributor.authorMaia-Matos, Mário
dc.contributor.authorBorges-Ferro, Amadeu
dc.date.accessioned2024-04-04T11:41:45Z
dc.date.available2024-04-04T11:41:45Z
dc.date.issued2024-03
dc.description.abstractFixation aims to preserve biological tissues and their components against natural degradation providing them with the necessary robustness to withstand further processing. The most used fixative is 10% natural buffered formalin (NBF), which offers some advantages over other solutions. However, it is considered a mutagenic and carcinogenic agent by the International Agency for Research on Cancer (IARC). To reduce the associated risk, other alternatives have been investigated. The working solution with FineFix has a concentration of 70% ethanol and, according to the patent, its additives mitigate the disadvantages associated with alcoholic fixatives. This review aims to assess the existing information regarding the fixation quality of FineFix, considering macroscopic, histochemical, and immunohistochemical findings, to determine whether pathology laboratories can adopt it.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationFilipe J, Silva M, Monteiro N, Maia-Matos M, Borges-Ferro A. Finefix® fixation in histopathological samples with macroscopic, histochemistry and immunohistochemistry assessment: a systematic literature review. In: II Congresso BioMedLab, Convento de S. Francisco (Coimbra), 1-3 de março de 2024.pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.21/17253
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherAssociação Portuguesa de Ciências Biomédicas Laboratoriaispt_PT
dc.relation.publisherversionhttps://abiomedlab.org/abstract-book-do-ii-congresso-da-biomedlab/pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectFineFixpt_PT
dc.subjectFixationpt_PT
dc.subjectMacroscopypt_PT
dc.subjectHistochemistrypt_PT
dc.subjectImmunohistochemistrypt_PT
dc.titleFinefix® fixation in histopathological samples with macroscopic, histochemistry and immunohistochemistry assessment: a systematic literature reviewpt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferencePlaceCoimbrapt_PT
person.familyNameMaia-Matos
person.familyNameBORGES FERRO
person.givenNameMário
person.givenNameAMADEU JOSÉ
person.identifier.ciencia-id501A-A09D-5140
person.identifier.ciencia-idFA16-8351-EB4A
person.identifier.orcid0000-0002-3450-5758
rcaap.rightsopenAccesspt_PT
rcaap.typeconferenceObjectpt_PT
relation.isAuthorOfPublication9a426513-2cfa-4c15-89eb-a38ee9f5aa16
relation.isAuthorOfPublicationf823b4bf-d2e4-456e-a7fa-b35180ff403f
relation.isAuthorOfPublication.latestForDiscovery9a426513-2cfa-4c15-89eb-a38ee9f5aa16

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