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Effectiveness of myopia control interventions: a systematic review of 12 randomized control trials published between 2019 and 2021

2023-03Journal article Open access
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dc.contributor.authorLança, Carla
dc.contributor.authorPang, Chi Pui
dc.contributor.authorGrzybowski, Andrzej
dc.date.accessioned2023-04-18T16:37:42Z
dc.date.available2023-04-18T16:37:42Z
dc.date.issued2023-03
dc.description.abstractPurpose: This study aims to investigate the effectiveness of interventions to control myopia progression. In this systematic review, the primary outcomes were mean differences (MD) between treatment and control groups in myopia progression (D) and axial length (AL) elongation (mm). Results: The following interventions were found to be effective (p < 0.001): highly aspherical lenslets (HAL, 0.80 D, 95% CI, 0.77-0.83; -0.35 mm, 95% CI -0.36 to -0.34), MiSight contact lenses (0.66 D, 95% CI, 0.63-0.69; -0.28 mm, 95% CI -0.29 to -0.27), low dose atropine 0.05% (0.54 D, 95% CI, 0.38-0.70; -0.21 mm, 95% CI-0.28 to -0.14), Biofinity +2.50 D (0.45 D, 95% CI, 0.29, 0.61; -0.24 mm, 95% CI -0.33 to -0.15), defocus incorporated multiple segments [DIMS] (0.44 D, 95% CI, 0.42-0.46; -0.34 mm, 95% CI -0.35 to -0.33) and ortho-k lenses (-0.24 mm, 95% CI -0.33 to -01.5). Conclusion: Low-dose atropine 0.01% was not effective in reducing AL progression in two studies. Treatment efficacy with low-dose atropine of 0.05% showed good efficacy. Spectacles (HAL and DIMS) and contact lenses (MiSight and Biofinity) may confer a comparable treatment benefit compared to atropine, to slow myopia progression.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationLança C, Pang CP, Grzybowski A. Effectiveness of myopia control interventions: a systematic review of 12 randomized control trials published between 2019 and 2021. Front Public Health. 2023;11:1125000.pt_PT
dc.identifier.doi10.3389/fpubh.2023.1125000pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.21/15906
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherFrontiers Mediapt_PT
dc.relation.publisherversionhttps://www.frontiersin.org/articles/10.3389/fpubh.2023.1125000/fullpt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectOphthalmologypt_PT
dc.subjectMyopiapt_PT
dc.subjectAxial lengthpt_PT
dc.subjectEfficacypt_PT
dc.subjectElongationpt_PT
dc.subjectProgressionpt_PT
dc.subjectTreatmentpt_PT
dc.subjectSystematic reviewpt_PT
dc.titleEffectiveness of myopia control interventions: a systematic review of 12 randomized control trials published between 2019 and 2021pt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.startPage1125000pt_PT
oaire.citation.titleFrontiers in Public Healthpt_PT
oaire.citation.volume11pt_PT
person.familyNameLança
person.givenNameCarla
person.identifier.ciencia-id601A-6412-BF2F
person.identifier.orcid0000-0001-9918-787X
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication0320b455-ee19-4670-8bf2-10dce9de1bec
relation.isAuthorOfPublication.latestForDiscovery0320b455-ee19-4670-8bf2-10dce9de1bec

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