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Exposure assessment to azole resistant mycobiota: a demand in high load occupational environments

dc.contributor.authorViegas, Carla
dc.contributor.authorZegre, Miguel
dc.contributor.authorCaetano, Liliana Aranha
dc.contributor.authorViegas, Susana
dc.date.accessioned2018-11-15T11:03:53Z
dc.date.available2018-11-15T11:03:53Z
dc.date.issued2018-09
dc.descriptionProjeto IPL/2016/W2E_ESTeSL; Projeto IPL/2018/AquaInvest_ESTeSL; ACT - Projeto 005DDB/12pt_PT
dc.description.abstractThe emergence of microbial drug resistance is a well-known threat to public health. However, although bacterial resistance to antibiotics is widely described, scientific knowledge is scarce about fungal drug resistance. Driven by this necessity several occupational environments were assessed and mycobiota and azole-resistant fungal species distribution was characterized aiming to suggest a refined protocol to tackle this public and occupational health menace. Swine, bakeries, and waste industry were assessed, and shortly data from aquaculture and dairies will be also available. Passive methods for sampling, besides active ones, were chosen in order to collect contamination from a longer period and specific environmental samples were obtained. The prevalence of azole resistance was determined through azole-supplemented media by seeding 150 µL of the wash suspension on Saboraud agar supplemented with 4 mg/L itraconazole, 1 mg/L voriconazole, or 0.5 mg/L posaconazole. Azole-resistant species were isolated in 40 out of 91 (44%); Aspergillus sp. and Mucorales order were identified in azole-supplemented media being non-susceptible to 1 mg/L voriconazole and non-susceptible to 4 mg/L itraconazole; Aspergillus section Nigri was isolated in three different azole-supplemented media. Considering the obtained results and the sampling strategy followed a protocol to ensure, besides mycobiota, the azole-resistant mycobiota exposure assessment, in high load occupational environments, will be suggested aiming to overcome the information scarcity related with this occupational risk factor.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationViegas C, Zegre M, Caetano LA, Viegas S. Exposure assessment to azole resistant mycobiota: a demand in high load occupational environments. In: 9th International Conference on the Science of Exposure Assessment, Manchester (UK), September 24-26, 2018.pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.21/9041
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.relationProjeto IPL/2016/W2E_ESTeSLpt_PT
dc.relationProjeto IPL/2018/AquaInvest_ESTeSLpt_PT
dc.relationACT - Projeto 005DDB/12pt_PT
dc.relation.publisherversionhttps://www.x2018.org/x2018-presentations/pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectOccupational healthpt_PT
dc.subjectOccupational exposurept_PT
dc.subjectAzole-resistancept_PT
dc.subjectMycobiotapt_PT
dc.subjectProjeto IPL/2016/W2E_ESTeSLpt_PT
dc.subjectProjeto IPL/2018/AquaInvest_ESTeSLpt_PT
dc.subjectProjeto 005DDB/12pt_PT
dc.titleExposure assessment to azole resistant mycobiota: a demand in high load occupational environmentspt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferencePlaceManchesterpt_PT
person.familyNameViegas
person.familyNameViegas
person.givenNameCarla
person.givenNameSusana
person.identifier248817
person.identifier.ciencia-idEE1E-C639-D70F
person.identifier.ciencia-idA919-7318-63DC
person.identifier.orcid0000-0002-1545-6479
person.identifier.orcid0000-0003-1015-8760
person.identifier.ridB-7217-2013
person.identifier.ridI-4053-2012
person.identifier.scopus-author-id55443609700
person.identifier.scopus-author-id35270591500
rcaap.rightsopenAccesspt_PT
rcaap.typeconferenceObjectpt_PT
relation.isAuthorOfPublicationb5fa5da4-50c3-4b88-ae20-1bc63cb485f7
relation.isAuthorOfPublication13115332-43f7-4048-a8a5-2f2b855a8c92
relation.isAuthorOfPublication.latestForDiscovery13115332-43f7-4048-a8a5-2f2b855a8c92

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