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Two-way MANCOVA: an application to public health

dc.contributor.authorRamos, M. R.
dc.contributor.authorCarolino, Elisabete
dc.contributor.authorOliveira, T.
dc.contributor.authorBicho, M.
dc.date.accessioned2013-08-21T13:10:32Z
dc.date.available2013-08-21T13:10:32Z
dc.date.issued2012-09
dc.description.abstractThe aim of this work is to use the MANCOVA model to study the influence of the phenotype of an enzyme - Acid phosphatase - and a genetic factor - Haptoglobin genotype - on two dependent variables - Activity of Acid Phosphatase (ACP1) and the Body Mass Index (BMI). Therefore it's used a general linear model, namely a multivariate analysis of covariance (Two-way MANCOVA). The covariate is the age of the subject. This covariate works as control variable for the independent factors, serving to reduce the error term in the model. The main results showed that only the ACP1 phenotype has a significant effect on the activity of ACP1 and the covariate has a significant effect in both dependent variables. The univariate analysis showed that ACP1 phenotype accounts for about 12.5% of the variability in the activity of ACP1. In respect to this covariate it can be seen that accounts for about 4.6% of the variability in the activity of ACP1 and 37.3% in the BMI.por
dc.identifier.citationRamos MR, Carolino E, Oliveira T, Bicho M. Two-way MANCOVA: an application to public health. In Numerical Analysis and Applied – ICNAAM 2012: International Conference of Numerical Analysis and Applied Mathematics. AIP Conf Proc. 2012;1479:1716-9por
dc.identifier.issn1551-7616
dc.identifier.urihttp://hdl.handle.net/10400.21/2616
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherAIP Publishingpor
dc.relation.publisherversionhttp://proceedings.aip.org/resource/2/apcpcs/1479/1/1716_1por
dc.subjectBiochemistrypor
dc.subjectCovariance analysispor
dc.subjectEnzymespor
dc.subjectGeneticspor
dc.subjectMolecular biophysicspor
dc.titleTwo-way MANCOVA: an application to public healthpor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage1719por
oaire.citation.startPage1716por
oaire.citation.titleAIP Conference Proceedingspor
oaire.citation.volume1479por
person.familyNameCarolino
person.givenNameElisabete
person.identifier.ciencia-id1216-EFA3-1E0F
person.identifier.orcid0000-0003-4165-7052
person.identifier.ridF-1012-2015
person.identifier.scopus-author-id25821697000
rcaap.rightsrestrictedAccesspor
rcaap.typearticlepor
relation.isAuthorOfPublication77930d39-ed34-44dc-a4a6-9bf833e5e688
relation.isAuthorOfPublication.latestForDiscovery77930d39-ed34-44dc-a4a6-9bf833e5e688

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